- Gut microbiota and health
- Phytochemicals and Antioxidant Activities
- Probiotics and Fermented Foods
- Microbial Metabolites in Food Biotechnology
- Fungal Biology and Applications
- Bioactive Compounds in Plants
- Parasites and Host Interactions
- Curcumin's Biomedical Applications
- Polysaccharides and Plant Cell Walls
- Phytochemical compounds biological activities
- Protein Hydrolysis and Bioactive Peptides
- Seaweed-derived Bioactive Compounds
- Animal Nutrition and Physiology
- Ginger and Zingiberaceae research
- Food composition and properties
- Parasite Biology and Host Interactions
- Diet, Metabolism, and Disease
- Pomegranate: compositions and health benefits
- Tea Polyphenols and Effects
- Proteins in Food Systems
- Clostridium difficile and Clostridium perfringens research
- Coccidia and coccidiosis research
- Genomics, phytochemicals, and oxidative stress
- Nutritional Studies and Diet
- Liver Disease Diagnosis and Treatment
University of Massachusetts Amherst
2017-2025
Ministry of Education of the People's Republic of China
2024-2025
Shaanxi Normal University
2024-2025
Henan Institute of Science and Technology
2015-2025
University of Massachusetts Boston
2025
Amherst College
2017-2021
South China Normal University
2021
Shanghai Veterinary Research Institute
2012-2015
Chinese Academy of Agricultural Sciences
2012-2015
Nanjing Agricultural University
2012
Abstract Dietary fibers (DFs) regulate host health through various mechanisms related to their dietary sources, specific physicochemical structures, fermentability, and physiological properties in the gut. Considering numerous types sources of DFs different properties, it is challenging yet important establish key for beneficial effects DFs. In this review, structures from fruits vegetables were summarized processing methods on DF discussed. Moreover, impacts gut microbial ecology,...
Multiple sclerosis (MS) has a complex genetic, immune and metabolic pathophysiology. Recent studies implicated the gut microbiome in MS pathogenesis. However, interactions between host system, metabolism diet have not been studied over time this disorder.We performed six-month longitudinal multi-omics study of 49 participants (24 untreated relapse remitting patients 25 age, sex, race matched healthy control individuals. Gut composition function were characterized using 16S metagenomic...
Strawberry (Fragaria chiloensis) is a major edible berry with various potential health benefits. This study determined the protective effects of whole strawberry (WS) against dextran-sulfate-sodium-induced colitis in mice. In colitic mice, dietary WS reduced disease activity index, prevented colon shortening and spleen enlargement, alleviated colonic tissue damages. The abundance proinflammatory immune cells was by mucosa, which accompanied suppression overproduction cytokines. Western...
Accumulating evidence suggests that the gut microbiota plays an important role in pathogenesis of colitis and its composition could be modulated by exposure to dietary components. Thus, it may possible ameliorate severity through administration Herein, we determined effects orally administered resveratrol on resulting inflammatory status a dextran sodium sulfate (DSS)-induced mouse model. Our results supported our hypothesis altered microbial restored community diversity DSS-treated mice....
Abstract The recent ban of titanium dioxide (TiO 2 ) as a food additive (E171) in France intensified the controversy on safety foodborne‐TiO nanoparticles (NPs). This study determines biological effects TiO NPs and obese non‐obese mice. Oral consumption (0.1 wt% diet for 8 weeks) (E171, 112 nm) (33 does not cause severe toxicity mice, but significantly alters composition gut microbiota, example, increased abundance Firmicutes phylum decreased Bacteroidetes Bifidobacterium Lactobacillus...
Oral administration of freeze-dried whole cranberry powder<italic>via</italic>diet inhibited colitis in dextran sodium sulfate-treated mice, which was associated with modification gut microbiota.
In this study, the preventive effect of tangeretin (TAN), a natural flavonoid derivative from citrus fruits, on dextran sulfate sodium (DSS)-induced colitis in mice was evaluated. Our results showed that dietary TAN (0.04% and 0.08% w/w diet) significantly reduced severity caused by DSS treatment mice, evidenced increased colon length, disease activity index, attenuated colonic tissue damages. Moreover, inhibited inflammatory response via down-regulating overexpression cytokines....
Although resveratrol (RES) is barely detectable in the plasma and tissues upon oral consumption, collective evidence reveals that RES presents various bioactivities vivo, including anti-inflammation anti-cancer. This paradox necessitates further research on profiling characterizing biotransformation of RES, as its metabolites may contribute profound biological effects. After 4-week administration, 11 were identified quantified mice by HPLC-MS/MS, dihydro-resveratrol (DHR), lunularin (LUN),...
Dietary nobiletin alleviated antibiotic-associated gut dysbiosis by maintaining the balance of intestinal microbiota and metabolism to enhance barrier function.
Concerns about the safety of food additives have intensified among consumers, scientists, and policymakers. Ensuring these is crucial to public health. Carrageenan (CGN), a common additive in industry, has become subject controversy, particularly regarding whether it can be degraded gastrointestinal tract, forming carrageenans (dCGNs) that may pose health risks. This study first identify Bacteroides xylanisolvens C3 as key gut bacterium involved degradation food-grade lambda-CGN (L-CGN)....
Scope Pleurotus eryngii , an edible mushroom, is widely consumed as a functional food for various health benefits due to its multiple bioactive components. There are growing interests in using whole‐food‐based strategies prevent colonic inflammation via potential synergistic interactions among different components within the whole foods. However, limited research focused on inhibitory effects of P. mushroom against inflammatory bowel disease (IBD). Methods and results The protective IBD...
The genus Bifidobacterium has been widely used in functional foods for health promotion due to its beneficial effects on human health, especially the gastrointestinal tract (GIT). In this study, we characterize anti-inflammatory potential of probiotic strain pseudocatenulatum G7, isolated from a healthy male adult. G7 secretion inhibited inflammatory response lipopolysaccharide (LPS)-stimulated RAW 264.7 macrophages. Moreover, oral administration bacteria alleviated severity colonic...
A novel protein with anti-inflammatory effects was isolated from <italic>Pleurotus eryngii</italic>.
Edible mushrooms are rich sources of bioactive components.
Combination of allyl isothiocyanate and sulforaphane produced a synergistic inhibition on lung cancer cell growth.