A5070760631- Protein Hydrolysis and Bioactive Peptides
- Biochemical effects in animals
- Proteins in Food Systems
- Nuts composition and effects
- Tryptophan and brain disorders
- Polysaccharides and Plant Cell Walls
- Neuroinflammation and Neurodegeneration Mechanisms
- SARS-CoV-2 and COVID-19 Research
- Antioxidant Activity and Oxidative Stress
- Phytochemicals and Antioxidant Activities
- Protein Tyrosine Phosphatases
- Polysaccharides Composition and Applications
- Seaweed-derived Bioactive Compounds
- Insect Utilization and Effects
- Horticultural and Viticultural Research
- Immune Cell Function and Interaction
- GABA and Rice Research
- RNA modifications and cancer
- Aquaculture Nutrition and Growth
- Biochemical Analysis and Sensing Techniques
- Bioactive Compounds and Antitumor Agents
- Tea Polyphenols and Effects
- Fibroblast Growth Factor Research
- Probiotics and Fermented Foods
- Long-Term Effects of COVID-19
Hubei University of Technology
2021-2024
Guangdong Academy of Agricultural Sciences
2021-2024
Shandong University
2019-2024
Ministry of Agriculture and Rural Affairs
2021-2024
First Affiliated Hospital of Jiangxi Medical College
2024
Jiangnan University
2022-2024
Nanchang University
2018-2024
Rutgers, The State University of New Jersey
2023-2024
Nanjing University of Chinese Medicine
2023-2024
Nanjing Drum Tower Hospital
2023-2024
Increasing level of inflammation and oxidative stress could lead to memory impairment. The purpose this study was determine the neuroprotective effects walnut peptides against deficits induced by lipopolysaccharide (LPS) in mice further explore underlying anti-inflammatory mechanisms LPS-elicited BV-2 cells. Results showed that protein hydrolysate (WPH) its low-molecular-weight fraction (WPHL) ameliorate LPS via normalizing inflammatory response brain, especially WPHL. Furthermore, 18 with...
Gut health is important for nutrition absorption, reproduction, and lactation in perinatal early weaned mammals. Although melatonin functions maintaining circadian rhythms preventing obesity, neurodegenerative diseases, viral infections, its impact on the gut microbiome function mediating through microbiota remain largely unexplored. In present study, of rats was monitoring after fecal transplantation (FMT) foster care (FC). The results showed that FMT FC increased intestinal villus...
The aim of this study was to determine the neuroprotective effects walnut protein hydrolysates (WPH) against memory deficits induced by sleep deprivation (SD) in rat and further identify characterize potent peptides glutamate-induced apoptosis PC12 cells. Results showed that a remarkable amelioration effect on behavioral performance Morris water maze test observed for WPH its low molecular weight fraction WPHL, especially WPHL. Additionally, reduction antioxidant defense (catalase,...
As the most abundant marine carotenoid extracted from seaweeds, fucoxanthin (FUC) is considered to have excellent neuroprotective activity. However, target of FUC for its properties remains largely unclear. Oxidative stress one initiating factors causing neuronal cell loss and necrosis, it also an important inducement Parkinson’s disease (PD). In present study, effect was assessed using a 6‐hydroxydopamine‐ (6‐OHDA‐) induced neurotoxicity model. suppressed 6‐OHDA‐induced accumulation...
The anchoring of the Cu cluster on Mo 2 C substrate can achieve a planar configuration, effectively boosting urea synthesis via one-step mechanism.
ABSTRACT A novel assay was developed for Daudi cells in which the antiviral (AV) and antiproliferative (AP) activities of interferon (IFN) can be measured simultaneously. Using this assay, conditions allowing IFN AV protection but no growth inhibition were identified selected. treated under these conditions, gene expression microarray analyses performed. The results analysis 25 genes associated with IFN-α activity. Upregulation 23 IFN-induced confirmed by using reverse transcription-PCR. Of...
Ameliorations of cholinergic system dysfunction and oxidative stress in neurodegenerative diseases were main approaches to improve memory disorder. Our previous investigation showed that anchovy protein hydrolysate (APH) could attenuate scopolamine-induced deficits mice by regulating acetylcholinesterase (AChE) activity. Therefore, peptides with AChE inhibitory activity APH explored identified this study, their possible neuroprotective mechanisms on glutamate induced apoptosis PC12 also...
Sleep deprivation negatively influences memory formation and consolidation, which leads to impairment associated with oxidative stress neurotrophic pathways. In this study, a sleep-deprived rat model was used evaluate the protective effects of round scad hydrolysates (RSH, 333 666 mg per kg bw) on underlying mechanisms. The result Morris water maze test revealed that RSH significantly reversed cognition deficits induced by sleep deprivation. Moreover, supplementation alleviated increasing...
Previous studies supposed that Amadori rearrangement products (ARPs) of peptides might have better umami-enhancing abilities. To confirm this, five ARPs (EP-ARP, AH-ARP, EE-ARP, β-AH-ARP, RFPHADF-ARP) were synthesized using a food-grade preparation method, and their chemical structures clearly demonstrated by mass spectrometry 1D/2D NMR. Sensory experiments showed had abilities than the corresponding in this research, though enhancing performance varied. synergistic effect with multiple...
The inactivated whole-virion vaccine, CoronaVac, is one of the most widely used coronavirus disease 2019 (COVID-19) vaccines worldwide. There a paucity data indicating durability immune response and impact imprinting induced by CoronaVac upon Omicron infection. In this prospective cohort study, 41 recipients triple-dose 14 unvaccinated individuals were recruited. We comprehensively profiled adaptive parameters in both groups, including spike-specific immunoglobulin (Ig) G IgA titers,...
Collagen peptides (CP), including tripeptides and elastin (EP), are known for their in vitro vivo anti-skin aging effects. Despite positive results animal models, the combination effects of CP EP bioavailability human studies, particularly young middle-aged women, remain underexplored. To evaluate an orally administered collagen drink combining on skin health women. A single-center, randomized, double-blind, parallel-controlled trial was conducted, utilizing WONDERLAB® fish tripeptide...
Summary Anchovy protein hydrolysates ( APH s) were prepared through hydrolysis for 2, 4 or 8 h ‐2, ‐4 and ‐8, respectively). The chemical analyses, in vitro assessments [antioxidant activity acetylcholinesterase (AchE) inhibitory activity] vivo mice tests evaluated. Results revealed that ‐8 exhibited the strongest reducing power AchE capacity IC 50 = 159.76 ± 0.03 mg mL −1 ), which may be due to its specific amino acid composition newly formed peptides. In addition, kinetics of acids...
Pro-AlaTyr-Cys-Ser (PAYCS) was susceptible to digestion and its memory improving activity linked the activation of Nrf2/ARE BDNF/CREB signaling.
In this study, anti-diabetic activity and potential mechanism of sea cucumber hydrolysates (SCH) were investigated in type II diabetic rats induced by streptozotocin. Results showed that SCH alleviated body weight loss, oral glucose tolerance insulin resistance rats. The fasting blood level was markedly decreased 40.39% after administration. Moreover, lipid metabolism disorders attenuated to near normal treatment. Mechanism studies the expressions PI3K, p-Akt, p-GSK-3β GLUT2/GLUT4...