A5074185398- Geotechnical Engineering and Soil Stabilization
- Geotechnical Engineering and Soil Mechanics
- Geotechnical Engineering and Underground Structures
- Nanoplatforms for cancer theranostics
- Metamaterials and Metasurfaces Applications
- Nanoparticle-Based Drug Delivery
- ATP Synthase and ATPases Research
- Advanced Antenna and Metasurface Technologies
- Mitochondrial Function and Pathology
- Gold and Silver Nanoparticles Synthesis and Applications
- Geotechnical and construction materials studies
- RNA and protein synthesis mechanisms
- RNA Interference and Gene Delivery
- Civil and Geotechnical Engineering Research
- Antenna Design and Analysis
- Axon Guidance and Neuronal Signaling
- Inflammasome and immune disorders
- Metal Alloys Wear and Properties
- Landslides and related hazards
- Wireless Communication Security Techniques
- Soil and Unsaturated Flow
- Photochromic and Fluorescence Chemistry
- Optical Polarization and Ellipsometry
- Non-Invasive Vital Sign Monitoring
- Photoacoustic and Ultrasonic Imaging
Anhui University
2023-2024
Shandong Tumor Hospital
2021-2024
Dalian Medical University
2021-2024
Shandong University
2021-2024
Shandong First Medical University
2021-2024
State Key Laboratory of Chemical Engineering
2023-2024
Tianjin University
2023-2024
Xi'an University of Technology
2024
Shenzhen University
2024
Harbin Institute of Technology
2024
Most mitochondrial proteins are synthesized as precursors in the cytosol and post-translationally transported into mitochondria. The surface protein Tom70 acts at interface of In vitro import experiments identified targeting receptor, particularly for hydrophobic carriers. Using vivo methods high-content screens, we revisit question function considerably expand set Tom70-dependent proteins. We demonstrate that crucial activity is its ability to recruit cytosolic chaperones outer membrane....
A major challenge in using nanocarriers for intracellular drug delivery is their restricted capacity to escape from endosomes into the cytosol. Here, we significantly enhance efficiency by accurately predicting and regulating transition pH (pH0) of peptides modulate endosomal capability. Moreover, inverting chirality peptide carriers, could further ability deliver nucleic acid drugs as well antitumor drugs. The resulting carriers exhibit versatility transfecting various cell types with a...
Nuclear lamin B1 (LMNB1) is a member of the nuclear protein family. LMNB1 can maintain and ensure stability structure influence process cell senescence by regulating chromatin distribution, DNA replication transcription, gene expression, cycle, etc. In recent years, several studies have shown that abnormal expression LMNB1, classical biomarker senescence, highly correlated with progression various malignant tumors; therefore considered new potential tumor marker therapeutic target. However,...
Gold nanoparticles have attracted enormous interest as potential theranostic agents. However, little is known about the long-term elimination and systemic toxicity of gold in literature. Hollow nanospheres (HAuNS) a class photothermal conducting agent that shown promises photoacoustic imaging, ablation therapy, drug delivery. It's very necessary to make clear biosafety HAuNS for its further application. We investigated cytotoxicity, complement activation, platelet aggregation polyethylene...
Vital signs monitoring in physical activity (PA) is of great significance daily healthcare. Impulse Radio Ultra-WideBand (IR-UWB) radar provides a contactless vital detection approach with advantages range resolution and penetration. Several researches have verified the feasibility IR-UWB when target keeps still. However, various body movements are induced by PA, which lead to severe signal distortion interfere extraction. To address this challenge, novel joint chest–abdomen cardiopulmonary...
An ultra pH-responsive peptide nanocarrier that can efficiently and precisely target cancer cells to release gene drugs was reported.
Photothermal therapy (PTT) employs photosensitizing agents, which are taken up by cells and generate heat when irradiated with near-infrared (NIR) light, to enable the photoablation of cancer cells. High absorption in NIR region is crucial for a agent achieve efficient PTT. Different combinations between gold nanoparticles fluorescent agents always influence their spectrum properties. Herein, we fabricated novel combination (doxorubicin, DOX, also popular chemotherapeutic agent) nanospheres...
Background and Objectives Deproteinization is an indispensable process for the elimination of antigenicity in xenograft bones. However, hydrogen peroxide (H2O2) deproteinized xenograft, which commonly used to repair bone defect, exhibits limited osteoinduction activity. The present study was designed develop a new method deproteinization compare osteogenic capacities pepsin bones with those conventional H2O2 ones. Methods Bones were or 8 hours. morphologies compared by HE staining. content...
Endometriosis is difficult to treat since the side effects of current therapeutic method and high recurrence rate; thus, newer safer approaches are urgently needed. This work investigates enhanced permeability retention effect CdTe quantum dots (QDs) hollow gold nanospheres (HAuNS) in endometriosis increase delivery HAuNS into lesion cells. The surface successfully conjugated with a TNYL peptide that has specific affinity for EphB4 receptor, which member Eph family receptor tyrosine kinases....
The hair follicle is the basis of regeneration, and dermal papilla one most important structures in regeneration. New intervention reversal strategies for loss may arise due to prevention oxidative stress. GC/MS analysis was used determine compounds contained NSO. Then, NSO applied DPC cell proliferation stress experiments. RNA-seq performed cells treated with minoxidil. quantitative real-time polymerase chain reaction (qRT-PCR) verify gene expression. effects on length, weight, number depth...
Inspired by the missing (new) link prediction and spurious existing identification in theory, this paper establishes an auxiliary optimization method for public transit route network (PTRN) based on prediction. First, applied to PTRN is described, reviewing previous studies, summary indices set its algorithms are collected experiment. Second, through analyzing topological properties of Jinan’s established Space R method, we found that a typical small-world with relatively large average...