A5048624860- Protein Hydrolysis and Bioactive Peptides
- Analytical Chemistry and Chromatography
- Biochemical Analysis and Sensing Techniques
- Polysaccharides and Plant Cell Walls
- Glycosylation and Glycoproteins Research
- Proteins in Food Systems
- Advanced Chemical Sensor Technologies
- Meat and Animal Product Quality
- Biochemical effects in animals
- Advanced Proteomics Techniques and Applications
- Biochemical and Structural Characterization
- Protein purification and stability
- Pharmacological Effects of Natural Compounds
- CRISPR and Genetic Engineering
- Seaweed-derived Bioactive Compounds
- Wound Healing and Treatments
- Polysaccharides Composition and Applications
- Metabolomics and Mass Spectrometry Studies
- Chromatography in Natural Products
- Microencapsulation and Drying Processes
- Cholinesterase and Neurodegenerative Diseases
- Ginseng Biological Effects and Applications
- Phytochemistry and biological activity of medicinal plants
- Moringa oleifera research and applications
- Gut microbiota and health
Wuyi University
2024-2025
Wuyi University
2021-2023
South China University of Technology
2012-2023
N-Lactoyl-amino acid derivatives (N-Lac-AAs) are of increasing interest as potential taste-active compounds. The complexity and diversity N-Lac-AAs pose a significant challenge to the effective discovery N-Lac-AAs. Therefore, structure-based virtual screening was used identify Virtual results showed that N-lactoyl-hydrophobic amino acids had higher affinity for taste receptors, specifically N-l-Lac-l-Trp. And then, N-l-Lac-l-Trp synthesized in yields 22.3% by enzymatic synthesis presence...
Summary Anchovy protein hydrolysates ( APH s) were prepared through hydrolysis for 2, 4 or 8 h ‐2, ‐4 and ‐8, respectively). The chemical analyses, in vitro assessments [antioxidant activity acetylcholinesterase (AchE) inhibitory activity] vivo mice tests evaluated. Results revealed that ‐8 exhibited the strongest reducing power AchE capacity IC 50 = 159.76 ± 0.03 mg mL −1 ), which may be due to its specific amino acid composition newly formed peptides. In addition, kinetics of acids...
The bioactive peptide PAYCS (Pro-Ala-Tyr-Cys-Ser) identified from anchovy hydrolysates has been reported to be positive in memory alleviation. gut microbiota-brain axis plays a vital role brain functions, which could affected by nutritional supplementation. Herein, we found that at different concentrations (PAYCS-L and PAYCS-H) showed various improving effects behavioral tests alleviation on oxidative as well inflammatory stress the scopolamine-induced AD mouse model. 16S rRNA results...
Short peptides have become the focus of recent research due to their variable bioactivities, good digestibility and wide existences in food-derived protein hydrolysates. However, high complexity samples, identifying short still remains a challenge. In this work, tool, named PeposX-Exhaust, was developed for peptide identification. Through validation with known peptides, PeposX-Exhaust identified all submitted spectra accuracy rate reached 75.36%, adjusted further 98.55% when top 5 candidates...
Summary Soya protein isolate ( SPI ) with or without added substrate‐like amino acid was subject to enzymatic hydrolysis catalysed by commercial proteases (Alcalase 2.4 L, flavourzyme and pancreatin). Addition of a small amount acids (amino acid: = 1: 2500, mol g −1 during would cause significantly P < 0.05) reduced recovery, increased degree hydrolysis, altered composition antioxidant activities hydrolysates. The hydrolysates prepared Asp, Arg Lys exhibited higher activity than the...
Previous studies have demonstrated that thermal processing in the presence of lactate and amino acids can produce taste-active N-lactoyl acids. This study aimed to investigate impact on sensory characteristics acid-hydrolyzed vegetable proteins (aHVP). The results showed processed aHVP exhibited enhanced kokumi, a milder umami taste, reduced bitterness treatment with 1% at 110 °C for 3 h or 3% 120 2 compared unprocessed samples. Partial orthogonal least-squares discriminant analysis variable...
Summary Surviving in the gastrointestinal tract is crucial for biopeptides to exert physiological effects vivo . To enrich elastase inhibitory peptides with high digestive stability, elastin was separated by using ultrafiltration and macroporous resin column, then changes activity, amino acid composition peptide profile of during vitro digestion were measured. The results revealed that fraction F3 eluted 40% ethanol displayed stability possibly due content Pro‐containing (20.25%)....
A novel immunomodulatory polysaccharide (LP4) with a molecular weight 6.31 × 104 g/mol was purified from fresh longan pulp. It composed of mannose, glucose, glucuronic acid, galactose, xylose, arabinose, galacturonic fucose, and rhamnose in molar percentage 36:31:10:7:4:4:3:2:2, mainly linked by (1→6)-β-Man, (1→4)-β-Glc (1→6)-α-Glc. LP4 can obviously enhance the phagocytosis macrophages promote proliferation lymphocytes. After treating (12.5-50 μg/ml), production IL-1β TNF-α significantly...