A5100460575- Spine and Intervertebral Disc Pathology
- Spinal Fractures and Fixation Techniques
- Protein Hydrolysis and Bioactive Peptides
- Biochemical Analysis and Sensing Techniques
- Biochemical effects in animals
- Cervical and Thoracic Myelopathy
- Advanced Chemical Sensor Technologies
- Pelvic and Acetabular Injuries
- Proteins in Food Systems
- Olfactory and Sensory Function Studies
- Meat and Animal Product Quality
- Advanced Glycation End Products research
- Medical Imaging and Analysis
- Tumors and Oncological Cases
- Insect Utilization and Effects
- Collagen: Extraction and Characterization
- GABA and Rice Research
- Parvovirus B19 Infection Studies
- Musculoskeletal pain and rehabilitation
- Consumer Attitudes and Food Labeling
- Cholinesterase and Neurodegenerative Diseases
- Histiocytic Disorders and Treatments
- Scoliosis diagnosis and treatment
- Psoriasis: Treatment and Pathogenesis
- Seaweed-derived Bioactive Compounds
Gansu University of Traditional Chinese Medicine
2025
Chinese People's Liberation Army
2025
Central South University of Forestry and Technology
2024-2025
Central South University
2024-2025
South China University of Technology
2015-2024
Xi'an Jiaotong University
2015-2024
Chaozhou Central Hospital
2024
Taiyuan University of Technology
2023
Dalian Medical University
2022-2023
Second Affiliated Hospital of Dalian Medical University
2022-2023
BACKGROUND:As an available new tool for spinal surgery, robotic technology holds great potential and has been demonstrated to have better clinical outcomes compared with traditional techniques. However, it not other assisted tools the treatment of lumbar degenerative disease. This article focused on studying such variances. MATERIAL AND METHODS:A total 176 pedicle screws were inserted in 39 patients using a spine robot (group 1), 134 implanted 28 navigational template 2), 234 51 by...
Targeted therapy to prevent the progression from acute chronic pain in cancer patients remains elusive. We developed three novel models mice that together recapitulate anatomical, temporal, and functional characteristics of head neck humans. Using pharmacologic genetic approaches these models, we identified interaction between protease-activated receptor 2 (PAR2) serine proteases be central importance. show such as trypsin induce a PAR2-dependent manner. Chronic is associated with elevated...
Tea as the most consumed beverage in world has received enormous attention for its promoting health benefits. The deleterious effect of α-dicarbonyls and AGEs formed Maillard reaction is also a long-term challenge. connection between two topics was main aim this review, to address update antiglycation mechanism tea polyphenols. By analyzing recent publications, we have covered across chemistry models, cell lines animal studies. polyphenols, particularly catechins, showed outstanding by...
BACKGROUND With the in-depth development of minimally invasive spine surgery in recent years, robot- and computer-assisted technologies have been increasingly used successfully applied to spinal surgery. MATERIAL AND METHODS We performed a retrospective analysis 60 patients with grade I or II lumbar spondylolisthesis who underwent transforaminal interbody fusion (MIS-TLIF) from January 2017 December 2017. A robot-assisted surgical system was 30 for pedicle screw placement. The other...
Ameliorations of cholinergic system dysfunction and oxidative stress in neurodegenerative diseases were main approaches to improve memory disorder. Our previous investigation showed that anchovy protein hydrolysate (APH) could attenuate scopolamine-induced deficits mice by regulating acetylcholinesterase (AChE) activity. Therefore, peptides with AChE inhibitory activity APH explored identified this study, their possible neuroprotective mechanisms on glutamate induced apoptosis PC12 also...
Previous studies supposed that Amadori rearrangement products (ARPs) of peptides might have better umami-enhancing abilities. To confirm this, five ARPs (EP-ARP, AH-ARP, EE-ARP, β-AH-ARP, RFPHADF-ARP) were synthesized using a food-grade preparation method, and their chemical structures clearly demonstrated by mass spectrometry 1D/2D NMR. Sensory experiments showed had abilities than the corresponding in this research, though enhancing performance varied. synergistic effect with multiple...
Background: 6-hydroxybenzothiazole-2-carboxamide is a novel, potent, and specific monoamine oxidase B inhibitor that can be used to study the structure of molecules come up with new ways protect neurons. Objective: The objective this work was create an effective model using derivatives 6- hydroxybenzothiazole-2-carboxamide establish dependable predictive foundation for development neuroprotective inhibitors treatment neurodegenerative diseases. Methods: construction optimization all...
This study aimed to investigate the protective effects of bovine elastin hydrolysates on UV-induced skin photoaging in mice and identify potent antiphotoaging peptides. Results showed that ingestion peptides could obviously ameliorate epidermis hyperplasia fibroblast apoptosis, increase content hydroxyproline water vivo ( p < 0.05). Furthermore, four with elastase inhibitory activity were purified identified, including GLPY, PY, GLGPGVG, GPGGVGAL. Interestingly, GLPY GPGGVGAL exhibited...
This study employed proline, glucose, and water to prepare natural deep eutectic solvents (NADES) through heating stirring. The Maillard reaction was then performed, producing a high yield of Amadori rearrangement product (ARP) physicochemical properties NADES were examined for impacts on the reaction. Water had dual function by promoting formation hydrogen bonding networks within when present at less than 15%, also working as diluting agent that could potentially disturb its structure...
A typical glycoconjugate of glutamic acid, namely, N-(β-d-deoxyfructos-1-yl)-l-glutamic was successfully synthesized as the primary isomer in a yield 96.08% using food-grade preparation method, and its chemical structure clearly demonstrated by mass spectrometry 1D/2D NMR. The reaction kinetics glucose acid were systematically studied to investigate effect lyophilization thermal treatment on conversion reactants their corresponding Amadori rearrangement product (ARP). Interestingly, besides...
Short peptides have become the focus of recent research due to their variable bioactivities, good digestibility and wide existences in food-derived protein hydrolysates. However, high complexity samples, identifying short still remains a challenge. In this work, tool, named PeposX-Exhaust, was developed for peptide identification. Through validation with known peptides, PeposX-Exhaust identified all submitted spectra accuracy rate reached 75.36%, adjusted further 98.55% when top 5 candidates...
Purpose: The purpose of this study was to investigate the feasibility Single-Photon Emission Computed Tomography/Computed Tomography (SPECT/CT) image-based radiomics in differentiating bone metastases from benign lesions patients with tumors. Methods: A total 192 132 (134 training group, 58 validation group) diagnosed vertebral or were enrolled. All images evaluated and independently by two physicians more than 20 years diagnostic experience for qualitative classification, imported into...