Rui Cai

ORCID: 0000-0001-6163-8823
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About
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Research Areas
  • Cancer-related molecular mechanisms research
  • Microbial Inactivation Methods
  • Probiotics and Fermented Foods
  • Listeria monocytogenes in Food Safety
  • Circular RNAs in diseases
  • Identification and Quantification in Food
  • Phytochemicals and Antioxidant Activities
  • Adipose Tissue and Metabolism
  • Fermentation and Sensory Analysis
  • MicroRNA in disease regulation
  • Biopolymer Synthesis and Applications
  • RNA modifications and cancer
  • RNA Research and Splicing
  • Biochemical and biochemical processes
  • Mycotoxins in Agriculture and Food
  • Biosensors and Analytical Detection
  • Meat and Animal Product Quality
  • Microbial Metabolites in Food Biotechnology
  • Nanocomposite Films for Food Packaging
  • Diet and metabolism studies
  • Essential Oils and Antimicrobial Activity
  • GABA and Rice Research
  • Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
  • Adipokines, Inflammation, and Metabolic Diseases
  • Reproductive System and Pregnancy

Northwest University
2022-2024

Northwest A&F University
2015-2024

Anhui Medical University
2024

Anhui University of Traditional Chinese Medicine
2024

West China Second University Hospital of Sichuan University
2024

Sichuan University
2024

West China Hospital of Sichuan University
2024

Beijing Hospital of Traditional Chinese Medicine
2024

Capital Medical University
2024

Southwest University
2018-2022

Abstract Recent studies demonstrate the functions of long non-coding RNAs (lncRNAs) in mediating gene expression at transcriptional or translational level. Our previous study identified a Sirt1 antisense (AS) lncRNA transcribed from AS strand. However, its role and regulatory mechanism is still unknown myogenesis. Here, functional analyses showed that overexpression promoted myoblast proliferation, but inhibited differentiation. Mechanistically, was found to activate sense gene, . The...

10.1038/srep21865 article EN cc-by Scientific Reports 2016-02-23

Gut health is important for nutrition absorption, reproduction, and lactation in perinatal early weaned mammals. Although melatonin functions maintaining circadian rhythms preventing obesity, neurodegenerative diseases, viral infections, its impact on the gut microbiome function mediating through microbiota remain largely unexplored. In present study, of rats was monitoring after fecal transplantation (FMT) foster care (FC). The results showed that FMT FC increased intestinal villus...

10.1016/j.redox.2023.102829 article EN cc-by-nc-nd Redox Biology 2023-07-28

Summary The aim of this study was to investigate the antibacterial activity and mechanism cinnamic acid chlorogenic against Alicyclobacillus acidoterrestris . Minimum inhibitory concentrations were 0.375 2.0 mg mL −1 , minimum bactericidal 0.50 4.0 respectively. apple juice ingredients had little influence on inactivation A. After treatment with acid, morphology cells severely destroyed; leakage nucleic acids proteins increased significantly. SDS ‐ PAGE investigation bacterial proved that...

10.1111/ijfs.14051 article EN International Journal of Food Science & Technology 2018-12-11

Obesity is closely associated with numerous adipogenic regulatory factors, including coding and non-coding genes. Long noncoding RNAs (lncRNAs) play a major role in adipogenesis. However, differential expression profiles of lncRNAs inguinal white adipose tissue (iWAT) between wild-type (WT) ob/ob mice, as well their roles adipogenesis, are not understood. Here, total 2809 were detected the iWAT WT mice by RNA-Sequencing (RNA-Seq), 248 novel lncRNAs. Of them, 46 expressed differentially...

10.3390/cells8050477 article EN cc-by Cells 2019-05-18

Abstract Background Intramuscular fat (IMF) content is a vital parameter for assessing pork quality. Increasing evidence has shown that microRNAs (miRNAs) play an important role in regulating porcine IMF deposition. Here, novel miRNA implicated adipogenesis was found, and its effect regulatory mechanism were further explored with respect to intramuscular preadipocyte proliferation differentiation. Results By adipose tissue sequencing analysis, we found miR-146a-5p potential regulator of...

10.1186/s40104-020-00525-3 article EN cc-by Journal of Animal Science and Biotechnology/Journal of animal science and biotechnology 2021-02-03

A. acidoterrestris has been identified as the target bacterium in fruit juice production due to its high resistance standard heat treatment. Multiple studies have shown that cold plasma can effectively inactivate pathogenic and spoilage microorganisms juices. However, we are aware of only a few used acidoterrestris. In this study, inactivation efficacy was determined using plate count method described biphasic model. The effects food matrix, input power, gas flow rate, treatment time on were...

10.3390/foods12071531 article EN cc-by Foods 2023-04-04

Abstract Background Pork quality is affected by the type of muscle fibers, which closely related to meat color, tenderness and juiciness. Exosomes are tiny vesicles with a diameter approximately 30–150 nm that secreted cells taken up recipient mediate communication. Exosome-mediated muscle-fat tissue crosstalk newly discovered mechanism may have an important effect on intramuscular fat deposition quality. Various adipose tissue-derived exosomes been identified, but identification function...

10.1186/s40104-024-01029-0 article EN cc-by Journal of Animal Science and Biotechnology/Journal of animal science and biotechnology 2024-06-02

To explore the mechanism of Circ-MYOCD back-splicing and its regulatory role in myocardial hypertrophy. Sanger sequencing RNase R assays were performed to verify circularity stability Circ-MYOCD, whose subcellular distribution was determined by nuclear-cytoplasmic fractionation. Bioinformatics analysis mass spectrometry from pull-down conducted predict RNA-binding proteins (RBPs) interacting with Circ-MYOCD. In rat cardiomyocytes H9C2 cells, effects HNRNPH1 HNRNPL knockdown overexpression on...

10.12122/j.issn.1673-4254.2025.03.16 article EN PubMed 2025-03-20

Skeletal muscle is the dominant executant in locomotion and regulator energy metabolism. Embryonic myogenesis postnatal growth are controlled by a cascade of transcription factors epigenetic regulatory mechanisms. MicroRNAs (miRNAs), family non-coding RNA 22 nucleotides length, post-transcriptionally regulates expression mRNA pairing seed sequence to 3' UTR target mRNA. Increasing evidence has demonstrated that miRNAs important regulators diverse myogenic processes. The profiling miRNA...

10.1080/15476286.2017.1279786 article EN RNA Biology 2017-01-13
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