A5100746959- Phytochemicals and Antioxidant Activities
- Gut microbiota and health
- Antioxidant Activity and Oxidative Stress
- Ginseng Biological Effects and Applications
- Essential Oils and Antimicrobial Activity
- Food Quality and Safety Studies
- Microbial Metabolites in Food Biotechnology
- Pharmacological Effects of Natural Compounds
- Natural product bioactivities and synthesis
- Genomics, phytochemicals, and oxidative stress
- Phytochemistry and biological activity of medicinal plants
- Alcohol Consumption and Health Effects
- Polysaccharides and Plant Cell Walls
- Biofuel production and bioconversion
- Herbal Medicine Research Studies
- Liver Disease Diagnosis and Treatment
- Meat and Animal Product Quality
- Polysaccharides Composition and Applications
- Algal biology and biofuel production
- Tea Polyphenols and Effects
- Microbial Metabolic Engineering and Bioproduction
- Antibiotic Resistance in Bacteria
- Mycotoxins in Agriculture and Food
- Exercise and Physiological Responses
- Advanced Glycation End Products research
State Key Laboratory of Food Science and Technology
2016-2025
Jiangnan University
2016-2025
Central South University
2022-2025
Hunan Cancer Hospital
2022-2025
Southwest University
2024-2025
South China Agricultural University
2012-2024
Guiyang Medical University
2024
Affiliated Hospital of Guizhou Medical University
2024
Fudan University
2018-2024
Affiliated Eye Hospital of Wenzhou Medical College
2024
ABSTRACT: The mango is a rich source of various polyphenolic compounds. major polyphenols in the terms antioxidative capacity and/or quantity are: mangiferin, catechins, quercetin, kaempferol, rhamnetin, anthocyanins, gallic and ellagic acids, propyl methyl gallate, benzoic acid, protocatechuic acid. nutraceutical pharmaceutical significance which special polyphenol has been extensively demonstrated continues to attract much attention especially its potential combat degenerative diseases...
In the face of alarming rise in global antimicrobial resistance, only a handful novel antibiotics have been developed recent decades, necessitating innovations therapeutic strategies to fill void antibiotic discovery. Here, we established screening platform mimicking host milieu select adjuvants and found three catechol-type flavonoids—7,8-dihydroxyflavone, myricetin, luteolin—prominently potentiating efficacy colistin. Further mechanistic analysis demonstrated that these flavonoids are able...
Some key secondary metabolism genes are important for driving the infection process of entomopathogenic fungi; however, their chemical substance basis has not been well investigated. Here, mixtures polyol lipids discovered, which synthesized through iterative chain transfer-esterification-hydrolysis cycles catalyzed by serine hydrolase during release online highly reducing polyketide intermediates. Importantly, an in vivo gene knockout experiment revealed that synthesis is necessary rodlet...
Dried ground leaves of Psidium guajava L. (guava) were extracted by water and aqueous ethyl alcohol 50% (1:10) ratio, the total phenolic content in extracts was determined spectrophotometrically according to Folin- Ciocalteu's phenol method calculated as gallic acid equivalent (GAE). Remarkably high 575.3 +/-15.5 511.6+/-6.2 mg GAE/g dried weight material (for ethanol guava leaf extracts, respectively) obtained. The antioxidant activity lyophilized at ambient temperature means a...
Abstract The mangos' popularity is on the rise due to its high nutraceutic and pharmaceutical value. mango unique because each of parts—fruit, pulp, peel, seed, leaves, flowers bark—are utilizable. Polyphenolic compounds related bioactivity in fruit are higher peel than pulp highest leaves stem barks. There various polyphenols mango, but Mangiferin, abundant bioactive. Synergy among mocro-elements extracts responsible for their as compared pure isolated explains use management degenerative...
An increasing number of studies suggest that the renal proximal tubule is a site injury in diabetic nephropathy (DN), and progressive tubulointerstitial fibrosis an important mediator kidney dysfunction DN. In this study, we observed increased expression activation YAP (yes-associated protein) epithelial cells (RPTC) patients with diabetes mouse kidneys. Inducible deletion Yap specifically RPTC or administration inhibitor verteporfin significantly attenuated fibrosis. EGFR-dependent...
Background Increasing evidence indicates that renal recovery from AKI stems dedifferentiation and proliferation of surviving tubule epithelial cells. Both EGF receptor (EGFR) the Hippo signaling pathway are implicated in cell differentiation, previous studies showed activation EGFR proximal cells (RPTCs) plays a critical role ischemia-reperfusion injury (IRI). In this study, we explored RPTC Yes-associated protein (YAP) transcriptional coactivator with PDZ binding motif (TAZ), two key...