A5039304485- Thyroid Disorders and Treatments
- Bone health and osteoporosis research
- Thyroid Cancer Diagnosis and Treatment
- Heart Rate Variability and Autonomic Control
- Neuroscience of respiration and sleep
- SARS-CoV-2 and COVID-19 Research
- HIV/AIDS drug development and treatment
- COVID-19 and Mental Health
- Bacterial Infections and Vaccines
- Growth Hormone and Insulin-like Growth Factors
- Vitamin D Research Studies
- HIV Research and Treatment
- Cardiovascular Health and Disease Prevention
- HIV/AIDS Research and Interventions
- COVID-19 epidemiological studies
- Otolaryngology and Infectious Diseases
- Attention Deficit Hyperactivity Disorder
- Pharmacogenetics and Drug Metabolism
- Hormonal and reproductive studies
- Full-Duplex Wireless Communications
- Nutritional Studies and Diet
- Amoebic Infections and Treatments
- Polyomavirus and related diseases
- Neonatal Health and Biochemistry
- Children's Physical and Motor Development
Instituto Butantan
2023-2025
Hospital Universitário da Universidade de São Paulo
2016-2020
Bayer (United States)
2020
Universidade de São Paulo
2016-2018
Subclinical hypothyroidism (SCH) is associated with an increased cardiovascular risk, but little information available about its association high-sensitivity C-reactive protein (hs-CRP).This study aims to analyze the between SCH and hs-CRP using baseline data from Brazilian Longitudinal Study of Adult Health (ELSA-Brasil).The has a cross-sectional design. We included subjects normal thyroid function (thyroid-stimulating hormone, TSH, 0.4-4.0 μIU/ml free thyroxine, fT4, 10.3-24.45 pmol/l)...
Abstract BACKGROUND There is little available data on carotid–femoral pulse wave velocity (cf-PWV) in subjects with subclinical hypothyroidism (SCH). We aimed to analyze the association between SCH and cf-PWV using baseline from Brazilian Longitudinal Study of Adult Health (ELSA–Brasil). METHODS included normal thyroid function (thyrotropin (TSH): 0.4–4.0 mIU/l, free thyroxine (FT4: 0.8–1.9ng/dl) (TSH > 4.0 mIU/l FT4) evaluated for a cross-sectional analysis. excluded individuals...
Summary Objective There is little information about the association between thyrotrophin (TSH) levels and coronary artery calcification (CAC). Our aim was to analyse TSH quintiles subclinical atherosclerosis measured by CAC, using baseline data from Brazilian Longitudinal Study of Adult Health (ELSA‐Brasil). Design Cross‐sectional study. Patients We excluded individuals medications that affect thyroid function who self‐reported cardiovascular disease. included euthyroid subjects with...
The association between subclinical thyroid dysfunctions and autonomic modulation changes has been described by many studies with conflicting results. We aimed to analyze the hyperthyroidism (SCHyper), hypothyroidism (SCHypo), heart rate variability (HRV) using baseline from ELSA-Brasil. SCHyper SCHypo were classified use of medication treat disorders, thyrotropin levels respectively above under reference range, normal free thyroxine levels. For HRV, participants underwent 10 min in supine...
Meningococcal meningitis is a public health problem. The aim of this study was to describe the clinical characteristics patients with meningococcal meningitis, and identify associated factors mortality. This retrospective study, between 2006 2011, at referral center in São Paulo, Brazil. Logistic regression analysis used We included 316 patients. median age 16 years (IQR: 7-27) 60% were male. triad: fever, headache neck stiffness observed 89% cerebrospinal pleocytosis, elevated protein...
1. Introduction and General Concepts The pandemic resulting from the novel coronavirus (SARS-CoV-2) infection, named COVID-19, emerged in Wuhan, China, December 2019., Since then, millions of people around world have been affected hundreds thousands died. virus spreads mainly person to person,, directly via airways or indirectly through contact with contaminated surfaces objects. Respiratory infections occur transmission virus-filled droplets (> 5 μm, approximate extension 1.5 m) aerosols [...]
Data on the association between subclinical thyroid dysfunction and coronary artery disease (CAD) is scarce. We aimed to analyze function CAD using baseline data from Brazilian Longitudinal Study of Adult Health (ELSA-Brasil). included subjects with normal (0.4-4.0 mIU/L, free thyroxine, FT4, or 0.8 1.9 ng/dL), hypothyroidism (SCHypo; TSH>4.0 mIU/L FT4), hyperthyroidism (SCHyper; TSH<0.4 FT4) evaluated by computed tomography angiography. excluded individuals medications that interfere in...
Tuberculous and cryptococcal meningitis (TBM CM) are the most common causes of opportunistic in HIVinfected patients from resource-limited settings, differential diagnosis is challenging.To compare clinical basic cerebrospinal fluid (CSF) characteristics between TBM CM HIV-infected patients.A retrospective analysis was conducted clinical, radiological laboratory records 108 98 with culture-proven CM, respectively. The were admitted at a tertiary centre São Paulo, Brazil. A logistic...
The present study aimed to evaluate the effectiveness of two doses CoronaVac in preventing SARS-CoV-2 symptomatic disease with virological confirmation, as well prevention COVID-19 moderate and severe cases. A test-negative unmatched case-control design was used, which cases were patients suspected (presenting at least following symptoms: fever, chills, sore throat, headache, cough, runny nose, olfactory or taste disorders) controls those whose test negative. As for exposure, participants...
Even though darunavir/ritonavir (DRV/r) has high potency and a greater genetic barrier, there are few studies on the long-term effectiveness of DRV/r-based salvage therapy in people living with HIV (PLWH) low middle-income countries. This retrospective cohort study, from São Paulo, Brazil, included ART-experienced PLWH aged ≥18 years virological failure (VF) who had started DRV/r plus an optimized background regimen (OBR) between 2008 2012. The proportion patients viral load (VL) <50...
The relationship between thyroid-stimulating hormone (TSH) and lipoprotein subfractions by Vertical Auto Profile (VAP) is unclear. We aimed to evaluate profiles according TSH levels in euthyroid individuals.Material Methods: Cross-sectional analysis of 3,525 participants from the Brazilian Longitudinal Study Adult Health (ELSA-Brasil) with no previous thyroid disease who were not on lipid-lowering medication. Total-cholesterol its fractions, subfractions, triglycerides, triglyceride-rich...