Ralph George

ORCID: 0000-0003-1457-1229
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About
Contact & Profiles
Research Areas
  • Breast Cancer Treatment Studies
  • Breast Lesions and Carcinomas
  • Hidradenitis Suppurativa and Treatments
  • Colorectal and Anal Carcinomas
  • Anorectal Disease Treatments and Outcomes
  • Global Cancer Incidence and Screening
  • Breast Implant and Reconstruction
  • Chemotherapy-related skin toxicity
  • Cancer and Skin Lesions
  • Economic and Financial Impacts of Cancer
  • BRCA gene mutations in cancer
  • Cancer survivorship and care
  • CAR-T cell therapy research
  • Cancer Diagnosis and Treatment
  • MRI in cancer diagnosis
  • Cutaneous Melanoma Detection and Management
  • Bariatric Surgery and Outcomes
  • Nonmelanoma Skin Cancer Studies
  • Clinical practice guidelines implementation
  • Radiomics and Machine Learning in Medical Imaging
  • Advances in Oncology and Radiotherapy
  • Body Contouring and Surgery
  • Inflammatory mediators and NSAID effects
  • Soft tissue tumor case studies
  • Multiple and Secondary Primary Cancers

Sree Gokulam Medical College and Research Foundation
2025

University of Toronto
2015-2024

St. Michael's Hospital
2011-2023

Canadian Imperial Bank of Commerce (Canada)
2021

St Michaels Hospital
2013-2020

Women's College Hospital
2020

Ontario Clinical Oncology Group
2012

Health Sciences Centre
2012

Hamilton Health Sciences
2012

Sunnybrook Health Science Centre
2012

To provide recommendations on the best strategies for management and timing treatment (surgical radiotherapeutic) of axilla patients with early-stage breast cancer.Ontario Health (Cancer Care Ontario) ASCO convened a Working Group Expert Panel to develop evidence-based informed by systematic review literature.This guideline endorsed two 2017 use sentinel lymph node biopsy in cancer expanded that radiotherapy interventions, staging after neoadjuvant chemotherapy (NAC), mapping modalities....

10.1200/jco.21.00934 article EN Journal of Clinical Oncology 2021-07-19

Recent reports from North America and Europe have documented an annual increase in the incidence of differentiated thyroid carcinoma. We sought to investigate relation between rates detection, tumour size, age sex.Using Ontario Cancer Registry, we identified 7422 cases carcinoma diagnosed Jan. 1, 1990, Dec. 31, 2001. obtained pathology for a random 10% patients each year study period. The sample represented all Care regions. compared size patients' tumours by year, sex age.As expected,...

10.1503/cmaj.061730 article EN cc-by-nc-nd Canadian Medical Association Journal 2007-11-19

PURPOSE Patients with locally advanced breast cancer (LABC) typically undergo staging tests at presentation. If does not detect metastases, treatment consists of curative intent combined modality therapy (neoadjuvant chemotherapy, surgery, and regional radiation). Positron emission tomography-computed tomography (PET-CT) may more asymptomatic distant but the evidence is based on uncontrolled studies. METHODS For inclusion, patients had histological invasive ductal carcinoma TNM stage III or...

10.1200/jco.23.00249 article EN Journal of Clinical Oncology 2023-05-26

Purpose 2-[ 18 F]fluorodeoxyglucose (FDG) positron emission tomography (PET) is potentially useful in assessing lymph nodes and detecting distant metastases women with primary breast cancer. Patients Methods Women diagnosed operable cancer within 3 months underwent FDG-PET at one of five Ontario study centers followed by axillary node assessment (ALNA) consisting sentinel biopsy (SLNB) alone if (SLNs) were negative, SLNB dissection (ALND) or PET was positive, ALND SLNs not identified....

10.1200/jco.2011.38.1103 article EN Journal of Clinical Oncology 2012-03-06

Importance Various surgical approaches for hidradenitis suppurativa (HS) have been described in the literature, but nomenclature is inconsistent. Excisions as wide, local, radical, and regional with variable descriptions of margins. Deroofing procedures various though approach are generally more uniform. No international consensus has formed to globally standardize terminology HS procedures. Lack such agreement may contribute misunderstanding or misclassification procedural research studies...

10.1001/jamadermatol.2022.6266 article EN JAMA Dermatology 2023-02-22

Abstract Vaccinations are essential for controlling infectious diseases, but adverse events following immunization can occasionally occur. Febrile seizures, although rare, one such event typically associated with childhood vaccinations. This case report presents a 1.5-year-old boy who experienced febrile seizure diphtheria–pertussis–tetanus and measles–mumps–rubella vaccination. The occurred 36 h postvaccination during fever episode. Using the World Health Organization–Uppsala Monitoring...

10.4103/njpt.njpt_57_24 article EN National Journal of Pharmacology and Therapeutics 2025-01-01

Background: The use of preoperative breast magnetic resonance imaging (MRI) after the diagnosis cancer by mammography and/or ultrasound is inconsistent. Methods: After conducting a systematic review and meta-analysis comparing MRI versus no MRI, we reconvened to prepare clinical practice guideline on this topic. Results: Based evidence that improved recurrence, decreased rates reoperations (re-excisions or conversion mastectomy), increased detection synchronous contralateral cancer,...

10.3390/curroncol30070463 article EN cc-by Current Oncology 2023-06-30

Importance Although several clinician- and patient-reported outcome measures have been developed for trials in hidradenitis suppurativa (HS), there is currently no consensus on which are best suited use clinical practice. Identifying validated feasible applicable to the practice setting has potential optimize treatment strategies generate generalizable evidence that may inform guidelines. Objective To establish a core set of recommended appropriate interval within these should be applied....

10.1001/jamadermatol.2023.3282 article EN JAMA Dermatology 2023-09-27

<h3>Background:</h3> Hidradenitis suppurativa (HS) is a chronic debilitating folliculopilosebaceous disease that affects the skin most commonly in axilla, groin, inframammary, genital and buttock areas. Surgical intervention may be an appropriate option selected cases, but there risk of recurrence. The purpose this study was to assess results wide local excision (WLE) healthy subcutaneous fat with secondary intention healing patients HS who were under concurrent surgical dermatologic care....

10.1503/cjs.003119 article EN Canadian Journal of Surgery 2020-04-01

Extra-adrenal myelolipoma is a very rare type of tumour. Laparoscopic removal extra-adrenal has not been previously reported. We report the first case laparoscopic excision large perirenal myelolipoma.

10.5489/cuaj.824 article EN Canadian Urological Association Journal 2013-04-16

10.1043/1543-2165(2005)129<421:mptwld>2.0.co;2 article EN Archives of Pathology & Laboratory Medicine 2005-03-01

A 47-year-old woman presented with a 1-year history of palpable, asymptomatic breast mass. Her medical was unremarkable. There no family carcinoma. only medication consisted oral contraceptives, and she nonsmoker. solitary mass occupied most the upper outer quadrant left breast. No axillary lymphadenopathy identified. were palpable abnormalities right breast.The patient underwent ultrasound-guided core biopsies breast, results suggestive malignant fibroepithelial neoplasm. segmental...

10.5858/2005-129-421-mptwld article EN Archives of Pathology & Laboratory Medicine 2005-03-01

Abstract Hidradenitis Suppurativa (HS) is a chronic debilitating skin condition that impairs the productivity and quality of patients` lives. HS has recently drawn lots attention among scholars to further expand their knowledge but it still loads with uncertainties gaps be explored. This publication addresses these uncertainties, provides road‐map for researchers, clinicians from different disciplines future studies about HS. proceeding report first Symposium on Advances (SHSA), reviews...

10.1111/exd.13445 article EN Experimental Dermatology 2017-09-12

Given recent the debate over breast cancer screening that was reignited by 25-year follow-up data from Canadian National Breast Screening Study, Journal of Surgery commissioned a group experts to value mammography. We discuss study and summarize arguments in favour against mammography for average-risk patients. also provide summary recommendations use

10.1503/cjs.017514 article EN Canadian Journal of Surgery 2016-01-28
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