A5000939568- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Hidradenitis Suppurativa and Treatments
- Colorectal and Anal Carcinomas
- Growth Hormone and Insulin-like Growth Factors
- Diabetes Management and Research
- Diabetes and associated disorders
- Pituitary Gland Disorders and Treatments
- Chemotherapy-related skin toxicity
- Oral Health Pathology and Treatment
- Cardiac and Coronary Surgery Techniques
- Thyroid Disorders and Treatments
- Prenatal Screening and Diagnostics
- Adrenal Hormones and Disorders
- Bariatric Surgery and Outcomes
- Congenital Ear and Nasal Anomalies
- Dermatological and Skeletal Disorders
- Neurological and metabolic disorders
- Takotsubo Cardiomyopathy and Associated Phenomena
- Sepsis Diagnosis and Treatment
- Autoimmune and Inflammatory Disorders
- RNA Research and Splicing
- Renal and related cancers
- Olfactory and Sensory Function Studies
- Genetic and rare skin diseases.
- Pericarditis and Cardiac Tamponade
University of North Carolina at Chapel Hill
2020-2023
McGill University Health Centre
2007-2022
Ho Chi Minh City Medicine and Pharmacy University
2020
Montreal Children's Hospital
2009-2015
Royal Victoria Hospital
2012
Royal Victoria Regional Health Centre
2012
McGill University
2010-2011
University of Toronto
2005-2009
Hospital for Sick Children
2005-2009
SickKids Foundation
2005-2009
Hidradenitis suppurativa (HS) is a common and severely morbid chronic inflammatory skin disease that reported to be highly heritable. However, the genetic understanding of HS insufficient, limited genome-wide association studies (GWASs) have been performed for HS, which not identified significant risk loci.
Importance Various surgical approaches for hidradenitis suppurativa (HS) have been described in the literature, but nomenclature is inconsistent. Excisions as wide, local, radical, and regional with variable descriptions of margins. Deroofing procedures various though approach are generally more uniform. No international consensus has formed to globally standardize terminology HS procedures. Lack such agreement may contribute misunderstanding or misclassification procedural research studies...
Primary cicatricial alopecias (PCA) encompass several autoimmune disorders characterized by scarring hair loss. Many of these conditions are lymphocytic and thought to be driven T cell populations. Here, we sought characterize potential cell-hair follicle communication pathways in the microanatomical niche using spatial transcriptomics across 3 mammalian species including a novel mouse model, spontaneous disease companion dogs human archival diagnostic biopsies. Flow cytometry model skin...
Background: The transition to dolutegravir-containing antiretroviral therapy (ART) in low- and middle-income countries (LMICs) was complicated by an initial safety signal May 2018 suggesting that exposure dolutegravir at conception possibly associated with infant neural tube defects. On the basis of additional evidence, July 2019, World Health Organization recommended for all adults adolescents living HIV. Objective: To describe uptake disparities sex age group LMICs. Design: Observational...
Article Catch-up Growth in Severe Juvenile Hypothyroidism: Treatment with a GnRH Analog was published on March 1, 2004 the journal Journal of Pediatric Endocrinology and Metabolism (volume 17, issue 3).
We investigated the effect of insulin administered as part a hyperinsulinemic-normoglycemic clamp on protein metabolism after coronary artery bypass grafting (CABG) surgery. Eighteen patients were studied, with nine in control group receiving standard metabolic care and (5 mU·kg(-1)·min(-1)). Whole body glucose production, breakdown, synthesis, oxidation determined using stable isotope tracer kinetics (l-[1-(13)C]leucine, [6,6-(2)H2]glucose) before 6 h procedure. Plasma amino acids,...
The growth hormone (GH) stimulation protocols for clonidine and arginine tests are non-standardized can be lengthy. We examined the specificity of both using a shorter duration timed samples: 90 min 60 arginine.We retrospectively studied all children who had GH with to test deficiency (GHD). compared diagnostic accuracy reference new shortened (index).We reviewed 243 charts (11.4±4.1 years old; 74.5% males). combined was performed on 159 children, 29 (18.3%) tested positive GHD index test,...
Hidradenitis suppurativa (HS) often develops in pediatrics, but few interventional studies include pediatric patients.This dual analysis of a HS cohort and typical eligibility criteria adult trials aims to identify potential patient characteristics inclusion for future studies.This cross-sectional descriptive study is based on prospectively collected data registry from an clinic. We also queried 125 the Clinicaltrials.gov database information 61 systemic drug was analyzed.The mean abscess...
Context: Congenital hypothyroidism due to thyroid dysgenesis (CHTD) is a predominantly sporadic and nonsyndromic (NS) condition of unknown etiology. NS-CHTD shows 40-fold increase in relative risk among first-degree relatives (1 100 compared with birth prevalence 1 4000 the general population), but discordance rate between monozygotic (MZ) twins 92%. This suggests two-hit mechanism, combining genetic predisposition (incomplete penetrance inherited variants) postzygotic events (accounting for...