Nizameddin Koca

ORCID: 0000-0003-1457-4366
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About
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Research Areas
  • COVID-19 Clinical Research Studies
  • Liver Disease Diagnosis and Treatment
  • Systemic Lupus Erythematosus Research
  • Multiple Sclerosis Research Studies
  • Parathyroid Disorders and Treatments
  • SARS-CoV-2 and COVID-19 Research
  • Adipokines, Inflammation, and Metabolic Diseases
  • Metabolism, Diabetes, and Cancer
  • COVID-19 diagnosis using AI
  • Medical Imaging and Pathology Studies
  • Pancreatic function and diabetes
  • Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
  • Vascular Malformations and Hemangiomas
  • Radiomics and Machine Learning in Medical Imaging
  • Lipid metabolism and disorders
  • Central Venous Catheters and Hemodialysis
  • Eosinophilic Esophagitis
  • Healthcare and Venom Research
  • Obesity, Physical Activity, Diet
  • Emergency Medicine Education and Research
  • COVID-19 Impact on Reproduction
  • Pancreatitis Pathology and Treatment
  • Parkinson's Disease Mechanisms and Treatments
  • Sarcoidosis and Beryllium Toxicity Research
  • Growth Hormone and Insulin-like Growth Factors

Sağlık Bilimleri Üniversitesi
2018-2025

Bursa Technical University
2022-2025

University of Health Science
2024-2025

City Hospital
2024

Bursa Yuksek Ihtisas Egitim Ve Arastirma Hastanesi
2012-2023

State Hospital
2015-2023

University of Health Sciences
2022

University of Health Sciences Antigua
2022

Quanzhou Normal University
2021

Fujian Medical University
2021

Primary hyperparathyroidism (pHPT) is marked by mineral imbalances, often leading to nephrolithiasis and osteoporosis. While imaging remains the cornerstone for stone detection, there growing interest in biochemical markers that could enhance diagnostic accuracy. This study investigates calcium-to-magnesium (Ca/Mg) ratio as a novel biomarker nephrolithiasis, comparing its utility traditional 24-h urinary calcium excretion exploring broader clinical implications. In this retrospective of 367...

10.1038/s41598-025-86954-4 article EN cc-by-nc-nd Scientific Reports 2025-01-28

Background/aim: In this study, we aimed to evaluate the initial hematological findings analyzed on admission in confirmed COVID-19 patients who were transferred intensive care unit (ICU), predict possible indices. Materials and methods: Initial neutrophil lymphocyte ratio (NLR), platelet (PLR), monocyte (MLR), red cell distribution width (RPR), mean volume ratio, multiplied by count (LYM × PLT), of 695 with laboratory-confirmed investigated comparisons made between mild/moderate severe...

10.3906/sag-2007-97 article EN other-oa TURKISH JOURNAL OF MEDICAL SCIENCES 2020-10-02

This awareness study aimed to determine the ultrasound (US) examination rates in relation US-confirmed metabolic dysfunction-associated fatty liver disease (MAFLD) diagnosis internal medicine outpatients with type 2 diabetes (T2D) across Türkiye. A total of 6283 T2D patients were included this multicenter retrospective cohort conducted at 17 clinics The presence and indications for US performed within last 3 years recorded along MAFLD rates, laboratory findings on day US, referral rates....

10.5152/tjg.2024.24045 article EN cc-by The Turkish Journal of Gastroenterology 2025-04-08

Background: This study presents a comprehensive comparative analysis of two methods for arterial cannulation, palpation, and ultrasound guidance (USG), using sample 104 subjects each method. Methods: The primary objective was to evaluate the safety efficiency these techniques. Clinical laboratory parameters were recorded, including hemoglobin levels, platelet count, International Normalized Ratio (INR), albumin, total protein levels. number attempts procedure time documented procedure....

10.56016/dahudermj.1588898 article EN cc-by-nc-nd DAHUDER Medical Journal 2025-01-29

Metabolic dysfunction-associated steatotic liver disease (MASLD) in adolescents, including non-obese phenotypes, is an increasingly important public health issue. The current study investigated the use of controlled attenuation parameter (CAP) and stiffness measurement (LSM) as non-invasive tools, along with fibroblast growth factor-21 (FGF-21) cytokeratin-18 (CK-18), MASLD, obese healthy control groups, exploring metabolic hepatic profiles these groups. This cross-sectional recruited 195...

10.5152/tjg.2025.24760 article EN cc-by The Turkish Journal of Gastroenterology 2025-02-04

Objectives: This study aimed to evaluate the differences in anthropometric, clinical, laboratory, and radiological parameters between obese non-obese adolescents, focusing on role of FibroScan parameters, Cytokeratin-18 (CK-18), Fibroblast growth factor (FGF-21) assessing metabolic liver health. Methods: Anthropometric data were collected, blood pressure was measured. Laboratory including fasting glucose, insulin, HOMA-IR, enzymes, lipids, CK-18, FGF-21 levels, assessed. Liver stiffness...

10.18621/eurj.1619980 article EN The European Research Journal 2025-02-11

Objective: This paper aims to assess the prevalence of osteoporosis in patients with T1DM by studying influence main risk factors: BMI, calcium intake, vitamin D, lactose intolerance, and BMD, along fractures. Material Methods: Cross-sectional study 30 normal controls. BMD was measured using DEXA, further calculating daily D levels. Osteoporosis fracture were evaluated statistical analysis data obtained. Results: Patients had lower BMI (p < 0.001), intake L1-L4 Z scores = 0.002)...

10.31832/smj.1598017 article EN cc-by-nc Sakarya Medical Journal 2025-03-25

Aims: Nonalcoholic fatty liver disease (NAFLD) is a growing global health concern associated with chronic damage and metabolic comorbidities. Traditional anthropometric measures—such as body-mass index (BMI) waist circumference (WC), have known limitations. This study aimed to compare the diagnostic performance of novel obesity indices, including body shape (ABSI) roundness (BRI), conventional parameters in predicting NAFLD. Methods: A retrospective was conducted 430 Turkish adults (aged...

10.47582/jompac.1626490 article EN Journal of Medicine and Palliative Care 2025-03-23

Aim: To investigate the association of food addiction (FA) with psychosocial functioning and metabolic parameters in obese patients seeking weight-loss treatment. Methods: Two hundred twenty-four (male/female: 28/196) a mean age 44.5 ± 13.4 years body mass index (BMI) 41.6 7.2 were included study. After receiving sociodemographic data medical history, detailed physical examination, including anthropometric measurements, was performed by an experienced physician. Blood samples taken after...

10.1089/met.2019.0108 article EN Metabolic Syndrome and Related Disorders 2020-02-06

The mammalian target of rapamycin inhibitors is commonly preferred for solid organs transplantation. Although these drugs have various adverse effects, sirolimus-related lymphedema has been rarely reported. We report a case related to everolimus after kidney transplant. A 60-year-old woman successfully received deceased-donor kidney. Everolimus was added the treatment in postoperative month 3 owing other immunosuppressive drugs' effects. Edema occurred first on her feet year During months'...

10.6002/ect.2011.0139 article EN Experimental and Clinical Transplantation 2012-05-23

To measure the retinal capillary density quantitatively with optical coherence tomography angiography (OCTA) in patients rheumatoid arthritis (RA) and healthy controls (HCs), to evaluate relationship between OCTA findings RA disease activity.In this cross-sectional study, 106 eyes of 71 HCs were evaluated. divided into inactive (DAS28 < 3.2) active ≥ subgroups. Retinal plexus (CPD) was obtained from superficial (SCP), deep (DCP), radial peripapillary (RPC).In HCs, CPD (%) 50.99 ± 3.30 52.08...

10.1080/14397595.2020.1830740 article EN Modern Rheumatology 2020-09-30

Increased cardiovascular risk, represented by endothelial inflammation, probably starts with the very first course of type-2 diabetes (T2DM). Almost 85.2% all T2DM patients are overweight or obese. Thrombosis accounts 80% deaths in diabetes. The thrombotic-fibrinolytic equilibrium shifts favor thrombosis plasminogen activator inhibitor-1 (PAI-1). PAI-1 secretion is induced primarily CRP. overexpression predisposes unstable plaque development. contribution obesity and to this process not...

10.23736/s2724-6507.20.03158-2 article EN Minerva Endocrinology 2021-03-01

Background and objective Accurate identification of parathyroid adenoma (PA) is essential for minimally invasive treatment primary hyperparathyroidism (PHPT). The aim this study to evaluate the results hormone (PTH) assay in aspirates suspicious neck lesions clarify its reliability determining whether lesion origin. Methods A total 134 (104 imaging-suspected PA 30 concomitant thyroid nodules as a control group) 101 patients were retrospectively analyzed. Patients with positive, negative, or...

10.7759/cureus.45814 article EN Cureus 2023-09-23

Assessing nutritional status is vital for understanding and managing patients' clinical conditions. Controlling Nutritional Status (CONUT) score one of the most frequently used scores that evaluate caloric status, protein reserve, immunological response estimation. This study assesses critically ill its relationship with patient-related factors mortality. Electronic medical records 1687 Intensive Care Unit (ICU) patient files were reviewed from January 2019 to May 2023 retrospectively....

10.1097/md.0000000000036018 article EN cc-by-nc Medicine 2023-11-03

Abstract&#x0D; Hypereosinophilic Syndrome (HES) is caused by the uncontrolled proliferation of eosinophils generally associated with conditions such as allergic reactions or parasitic infections. This syndrome characterized excessive eosinophil production (&gt;1500/mm3) that persists for more than six months and cannot be explained secondary causes. HES symptoms can affect different body organs, usually, nonspecific include fever, malaise, fatigue, rash, shortness breath, myalgia.&#x0D; a...

10.56016/dahudermj.1391630 article EN cc-by-nc-nd DAHUDER Medical Journal 2024-01-26

This comprehensive study delves into the potential link between Neuromedin U (NmU) serum levels and development of non-alcoholic fatty liver disease (NAFLD), a condition increasing global prevalence significant public health concern. The research provides nuanced understanding disease's etiology by examining cohort 112 participants, including individuals with without NAFLD. meticulously considers spectrum variables such as demographic factors, body composition metrics, blood parameters....

10.1016/j.heliyon.2024.e27291 article EN cc-by-nc-nd Heliyon 2024-03-01

In the realm of granulomatous diseases, convergence pathophysiology, epidemiology, and therapeutic strategies presents a labyrinth complexity with far-reaching clinical implications. This review embarks on scholarly expedition through intricate landscape inflammation, dissecting multifaceted presentations ranging from infectious etiologies to enigmatic autoimmune disorders. With discerning eye recent advancements literature, we unravel nuanced interactions between host defenses granuloma...

10.56016/dahudermj.1459557 article EN cc-by-nc-nd DAHUDER Medical Journal 2024-04-28

Amidst the COVID-19 pandemic, hydroxychloroquine (HCQ) was widely administered despite limited data on its safety and efficacy. This study assesses acute chronic impacts of HCQ electrocardiography (ECG) parameters alongside effects azithromycin levofloxacin coadministration in patients with COVID-19. A comprehensive analysis conducted 109 receiving HCQ, or without Azithromycin and/or Levofloxacin, 51 long-term HCQ-treated Sjogren's syndrome (SS) patients. ECG parameters, including QTc...

10.1097/md.0000000000039039 article EN cc-by-nc Medicine 2024-08-09

: Metabolic dysfunction-associated steatotic liver disease (MASLD) and polycystic ovary syndrome (PCOS) share several pathophysiological mechanisms. While the prevalence of MASLD has been extensively studied in PCOS populations, occurrence among female adolescents with transient elastography (TE)-confirmed pediatric hepatology settings remains poorly characterized. This cross-sectional study aims to address this knowledge gap elucidate potential clinical biochemical differences between...

10.3390/jcm13195885 article EN Journal of Clinical Medicine 2024-10-02
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