- Essential Oils and Antimicrobial Activity
- Drug Solubulity and Delivery Systems
- Liver Disease Diagnosis and Treatment
- Cancer, Hypoxia, and Metabolism
- Diabetes Treatment and Management
- Insect Pest Control Strategies
- Nanocomposite Films for Food Packaging
- Analytical chemistry methods development
- Histone Deacetylase Inhibitors Research
- Ethnobotanical and Medicinal Plants Studies
- Medicinal Plants and Neuroprotection
- Peroxisome Proliferator-Activated Receptors
- Pharmacology and Obesity Treatment
- Spectroscopy and Chemometric Analyses
- Autophagy in Disease and Therapy
- Liver Disease and Transplantation
- Water Quality Monitoring and Analysis
- Peripheral Artery Disease Management
- Atherosclerosis and Cardiovascular Diseases
- Moringa oleifera research and applications
- Pharmacy and Medical Practices
- Cerebrovascular and Carotid Artery Diseases
- Sphingolipid Metabolism and Signaling
- Analytical Methods in Pharmaceuticals
- Crystallization and Solubility Studies
Banaras Hindu University
1979-2024
Ganesh Shankar Vidyarthi Memorial Medical College
2017-2023
Global University
2022
Harlem Hospital Center
2010
Mallinckrodt (Ireland)
2004
Pfizer (United States)
2004
Pharmaceutical Formulations (United States)
2002
University of Georgia
1997-2001
Lupin Pharmaceuticals (India)
1993-1994
Abstract Aflatoxin B 1 (AFB ), the natural polyketide produced by Aspergillus flavus , has a potent carcinogenic effect on humans as well animals. In present study, antifungal and anti-aflatoxigenic activity of chemically characterized Zingiber officinale essential oil (ZOEO) was investigated via in vitro analysis aided with molecular dynamics (MD) approaches. The GC–MS results revealed verbenol (52.41%) major component oil. ZOEO found to be 0.6 µl/ml 0.5 respectively. In-vitro targeting...
Abstract Nimbolide is a tetranortriterpenoid derived from the leaves and flowers of Azadirachta indica (Neem). It exhibits anticancer activity against variety cancers by modulating various crucial features, including cell proliferation, apoptosis, invasion metastasis. More importantly, cytotoxic effect nimbolide has also been observed T lymphoma, but underlying mechanisms are still unexplored. So far, no study conducted to observe on cancer metabolism. Therefore, present investigation was...
Objective: To investigate the solvent-dependent antimicrobial activity and phytochemical analysis of extracts Euphorbia hirta (leaves flowers) Murraya koenigii (leaves), as well to evaluate synergistic these medicinal with suitable antibiotic discs antibiotics susceptibility selected pathogenic microorganisms.Methods: The was screened through agar diffusion method microorganisms investigated using disc method. A combined methods were used for determination activities discs.Results: Among...
This study discusses the effect of formulation composition on physical characteristics and drug release behavior controlled‐release formulations made by roller compaction. The authors used mixture experimental design to components using diclofenac sodium as model substance varying relative amounts microcrystalline cellulose (Avicel), hydroxypropyl methylcellulose (HPMC), glyceryl behenate (Compritol). Dissolution studies revealed very little variability in release. t70 values for 13 were...
The objective of this work was to investigate potential interactions between anionic (Eudragit FS) and cationic RL) polymethacrylates multiple coatings a novel colonic drug delivery system. Aqueous films pure polymers Eudragit FS (FS) RL (RL) their superimposedfilm (FS-RL) were cast on glass slabs. ionic studied by analysing the dried using differential scanning calorimetry (DSC), Fourier transform-infrared spectroscopy (FT-IR), nuclear magnetic resonance (NMR). transition temperatures (Tg)...
AbstractAn in-vitro system for evaluating Nifedipine sustained release formulations has been developed. Two systems were evaluated to simulate sink conditions and correlate the with flow through dissolution in mechanism. For purpose of evaluation two commercial brands studied. The acidic biphasic was found be good rate nifedipine tablets. It can successfully utilized routine quality control work.