Nidia León‐Sicairos

ORCID: 0000-0003-1470-3383
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About
Contact & Profiles
Research Areas
  • Infant Nutrition and Health
  • Amoebic Infections and Treatments
  • Vibrio bacteria research studies
  • Parasitic Infections and Diagnostics
  • Viral gastroenteritis research and epidemiology
  • Escherichia coli research studies
  • Aquaculture disease management and microbiota
  • Iron Metabolism and Disorders
  • Antibiotic Resistance in Bacteria
  • Pediatric Hepatobiliary Diseases and Treatments
  • Child Nutrition and Water Access
  • COVID-19 Clinical Research Studies
  • Neonatal Respiratory Health Research
  • Antimicrobial Peptides and Activities
  • Salmonella and Campylobacter epidemiology
  • Neonatal and Maternal Infections
  • SARS-CoV-2 and COVID-19 Research
  • Diet and metabolism studies
  • Helicobacter pylori-related gastroenterology studies
  • Digestive system and related health
  • COVID-19 diagnosis using AI
  • RNA Interference and Gene Delivery
  • Probiotics and Fermented Foods
  • Acute Kidney Injury Research
  • Hemoglobinopathies and Related Disorders

Autonomous University of Sinaloa
2016-2025

Pediatric Hospital of Sinaloa
2015-2024

Asociación Civil Impacta Salud y Educación
2023

Mexican Social Security Institute
2021

Autoliv (Sweden)
2020

Departamento de Salud
2017

Instituto Politécnico Nacional
2005-2008

Center for Research and Advanced Studies of the National Polytechnic Institute
2005-2008

Hospital Vargas
2006

Autonomous University of Tamaulipas
2006

Vibrio cholerae is the causal organism of cholera epidemic, which mostly prevalent in developing and underdeveloped countries. However, incidences developed countries are also alarming. Because emergence new drug-resistant strains, even though several generic drugs vaccines have been over time, infections remain a global health problem that appeals for development novel against pathogen. Here, applying comparative proteomic reverse vaccinology approaches to exoproteome secretome pathogen, we...

10.1371/journal.pone.0052773 article EN cc-by PLoS ONE 2013-01-30

In 2004, more than 1,230 cases of gastroenteritis due to pandemic O3:K6 strains Vibrio parahaemolyticus were reported in southern Sinaloa, a state Northwestern Mexico. Recurrent sporadic arose from 2004 2010, spreading the south north. present study, was detected both environmental samples and clinical along Pacific coast Sinaloa during 2010. An evaluation made serotypes, distribution virulence genes, presence strains. A total 144 isolated (from sediment, seawater, shrimp), 154 isolated. 10...

10.1128/aem.06953-11 article EN Applied and Environmental Microbiology 2012-01-14

Diarrheagenic Escherichia coli (DEC) strains are a main cause of gastrointestinal disease in developing countries. In this study we report the epidemiologic surveillance 4-year period (January 2011 to December 2014) DEC causing acute diarrhea throughout Sinaloa State, Mexico. were isolated from outpatients all ages with (N = 1,037). Specific pathotypes identified by PCR-amplification genes encoding virulence factors. The adhesion phenotype and antibiotic resistance also investigated....

10.3389/fmicb.2016.01924 article EN cc-by Frontiers in Microbiology 2016-11-30

AIM: To assess the proportion of refractive errors in Mexican population that visited primary care optometry clinics fourteen states Mexico. METHODS: Refractive data from 676 856 patients aged 6 to 90y were collected Mexico between 2014 and 2015. The classified by spherical equivalent (SE), as follows: sphere+½ cylinder. Myopia (SE>-0.50 D), hyperopia (SE>+0.50 emmetropia (-0.50≤SE≤+0.50), astigmatism alone (cylinder≥-0.25 D). A negative cylinder was selected a notation. RESULTS: (95%...

10.18240/ijo.2017.05.23 article EN cc-by-nc-nd International Journal of Ophthalmology 2017-05-12

The COVID-19 diagnosis is difficult and ambiguous due to nonspecific symptoms. Further, data from Mexico arehospitable population-based without signs symptoms information. Thus, this work aims provide epidemiology information about the burden of in Mexican outpatients identify symptomatic profiles that could help early disease.From June September, epidemiological, clinical, demographic 482,413 individuals diagnosed by RT-PCR test for SARS-CoV-2 Salud Digna clinics were collected.We observed...

10.1016/j.ijid.2020.12.086 article EN cc-by International Journal of Infectious Diseases 2021-01-12

Nidia León-Sicairos, DSc, Fernando López-Soto, MSc, Magda Reyes-López, BSc, Delfino Godínez-Vargas, Cynthia Ordaz-Pichardo, DSc and Mireya de la Garza, DSc; Departamento Biología Celular, Centro Investigación y Estudios, Avanzados del I.P.N. Apdo. 14-740, México, D. F. 07000, México; Hospital Pediátrico Sinaloa, Depto. Investigación, Blvd. Constitución s/n, Col. Almada, Culiacán, Sinaloa 80200, México MSc; BSc; 14-740,México, Unidad Académica Multidisciplinaria Reynosa-Aztlán, Universidad...

10.3121/cmr.4.2.106 article EN Clinical Medicine & Research 2006-06-01

The aerobic oral and cloacal bacterial microbiota their antimicrobial resistance were characterized for 64 apparently healthy sea turtles captured at foraging grounds in Ojo de Liebre Lagoon (OLL), Baja California Sur (BCS), Mexico (Pacific Ocean) the lagoon system of Navachiste (LSN) Marine Area Influence (MAI), Guasave, Sinaloa (Gulf California). A total 34 black (Chelonia mydas agassizii) sampled OLL eight 22 olive ridley (Lepidochelys olivacea) LSN MAI, respectively from January to...

10.3389/fmicb.2015.00635 article EN cc-by Frontiers in Microbiology 2015-06-25

Rationale: The giant placental chorangioma is a non-trophoblastic tumor, characterized by vascular proliferation that invades the fetal side of placenta. This can lead to uteroplacental insufficiency and subsequent imbalance proangiogenic antiangiogenic factors, resulting in early-onset preeclampsia becoming an imminent obstetric emergency. diagnosis be suspected during prenatal stage through ultrasound confirmed histopathology. Patient concerns: case concerns 23-year-old female patient who...

10.1097/md9.0000000000000348 article EN cc-by Medicine Case Reports and Study Protocols 2025-01-03

Between September and October of 2004, more than 1230 cases gastroenteritis due to pandemic O3:K6 strains Vibrio parahaemolyticus (V. parahaemolyticus) were reported in the relatively small geographical area Southern Sinaloa, a state located Northwest Mexico. Since then, V. parahaemolyticus-associated have gradually increased prevalence spreading from south north. The present study conducted an epidemiological surveillance both environmental clinical samples along Pacific coast Sinaloa 2011...

10.3389/fmicb.2015.00221 article EN cc-by Frontiers in Microbiology 2015-03-24

To determine the frequency and distribution of ABO Rh (D) antigens and, additionally, investigate gene diversity structure Mexican populations.Blood groups were tested in 271,164 subjects from 2014 to 2016. The blood group was determined by agglutination using antibodies anti-A, Anti-B, Anti-D for factor, respectively.The overall population studied as follows: O: 61.82%; A: 27.44%; B: 8.93%; AB: 1.81%. For group, 95.58% people (D), 4.42% (d). Different distributions across regions found;...

10.1155/2018/1925619 article EN cc-by BioMed Research International 2018-01-01

Diarrheagenic E . coli (DEC) strains are one of the most important etiology factors causing diarrhea in children worldwide, especially developing countries. DEC have characteristic virulence factors; however, other supplemental genes (SVG) may contribute to development children. Therefore, this study aimed determine prevalence with southwestern Mexico and associate childhood symptoms, SVG, pathotypes diarrhea-causing strains. were isolated from 230 aged 0–60 months state Oaxaca, Mexico;...

10.1371/journal.pone.0300304 article EN cc-by PLoS ONE 2024-03-12

Lactoferrin (Lf), in its iron-free form, has been shown to inhibit the growth of pathogenic microorganisms. In light new agents control amoebiasis, microbicidal activity human and bovine Lf lactoferricin (bLfcin, fragment 4–14), each combined with metronidazole, main drug used was evaluated trophozoites Entamoeba histolytica. Both lactoferrins bLfcin were able kill amoebas a concentration-dependent manner. This killing effect modulated according culture age, pH, temperature. Parasites...

10.1139/o06-060 article EN Biochemistry and Cell Biology 2006-06-01

Screening for pathogenic Vibrio parahaemolyticus has become routine in certain areas associated with food-borne outbreaks. This study is an evaluation of the CHROMagar (CV) medium – PCR protocol and conventional method (TCBS (thiosulfate citrate bile salts sucrose) agar plus biochemical Wagatsuma tests) detection V. shrimp, water, sediment, stool samples collected biosurveillance endemic area northwestern Mexico. A total 131 environmental clinical were evaluated. The CV showed a...

10.1139/w10-108 article EN Canadian Journal of Microbiology 2011-02-01
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