A5089471811- Chronic Myeloid Leukemia Treatments
- Chronic Lymphocytic Leukemia Research
- Pain Management and Placebo Effect
- Eosinophilic Disorders and Syndromes
- Diabetes and associated disorders
- Lymphoma Diagnosis and Treatment
- Acute Lymphoblastic Leukemia research
- Pancreatic function and diabetes
- Diabetes Management and Research
- Acute Myeloid Leukemia Research
- Multiple Myeloma Research and Treatments
- Cytomegalovirus and herpesvirus research
- Renal Transplantation Outcomes and Treatments
- Balance, Gait, and Falls Prevention
- Complementary and Alternative Medicine Studies
- Cardiac Imaging and Diagnostics
- Privacy-Preserving Technologies in Data
- Frailty in Older Adults
- Histone Deacetylase Inhibitors Research
- Acute Ischemic Stroke Management
- Acne and Rosacea Treatments and Effects
- Advanced X-ray and CT Imaging
- Advanced MRI Techniques and Applications
- Dermatological diseases and infestations
- Cerebrovascular and Carotid Artery Diseases
Ludwig-Maximilians-Universität München
2016-2025
Zimmer Biomet (Germany)
2016-2025
Goethe University Frankfurt
2017-2024
LMU Klinikum
2017-2023
Helmholtz Zentrum München
2018-2021
German Center for Diabetes Research
2019-2021
Technical University of Munich
2019-2021
Institute of Diabetes Research
2019
German Center for Infection Research
2019
Klinikum rechts der Isar
2019
Purpose To determine the feasibility of computed tomography (CT)-based dynamic myocardial perfusion imaging for detection hemodynamically significant coronary artery stenosis, as defined with fractional flow reserve (FFR). Materials and Methods Institutional review board approval informed patient consent were obtained before enrollment in study. The study was HIPAA compliant. Subjects who suspected having or known to have disease underwent electrocardiographically triggered stress imaging....
Purpose Identifying true therapeutic progress in patients with acute myeloid leukemia (AML) requires a comparison of treatment strategies and results on the basis uniform patient selection. To foster comparability across five clinical studies, we introduced common standard arm combined general upfront randomization performed prospective analyses adjustment for differences prognostic baseline characteristics. Patients Methods Whereas studies' own regimens differed chemotherapies, risk...
To revise the German guidelines and recommendations for ensuring Good Epidemiological Practice (GEP) that were developed in 1999 by Society Epidemiology (DGEpi), evaluated revised 2004, supplemented 2008, updated 2014. The executive board of DGEpi tasked third revision GEP. was arrived as a result consensus-building process working group collaboration with other groups Association Medical Informatics, Biometry Epidemiology, Social Medicine Prevention (DGSMP), Region International Biometric...
OBJECTIVE Assessment of the predictive power The Environmental Determinants Diabetes in Young (TEDDY)-identified risk factors for islet autoimmunity (IA), type autoantibody appearing first, and 1 diabetes (T1D). RESEARCH DESIGN AND METHODS A total 7,777 children were followed from birth to a median 9.1 years age development autoantibodies progression T1D. Time-dependent sensitivity, specificity, receiver operating characteristic (ROC) curves calculated provide estimates their individual...
In addition to macrophages, multinucleated giant cells (MNGCs) are involved in the tissue reaction a variety of biomaterials. Especially case bone substitute materials it has been assumed that MNGCs osteoclasts, based on chemical and physical similarity many calcified matrix bony environment which they used. However, studies indicate these belong cell line foreign body (FBGCs), "inflammatory origin", although have shown possess both pro- also anti-inflammatory phenotype. Moreover, no...
Abstract Prognostic scores support clinicians in selecting risk-adjusted treatments and comparatively assessing different results. For patients with chronic-phase chronic myeloid leukemia (CML), four baseline prognostic are commonly used. Our aim was to compare the performance of arrive at an evidence-based score recommendation. In 2949 not involved any development, higher hazard ratios concordance indices comparison demonstrated best discrimination long-term survival ELTS score. a second...
The POInT study, an investigator initiated, randomised, placebo-controlled, double-blind, multicentre primary prevention trial is conducted to determine whether daily administration of oral insulin, from age 4.0 months 7.0 until 36.0 children with elevated genetic risk for type 1 diabetes, reduces the incidence beta-cell autoantibodies and diabetes.Infants aged Germany, Poland, Belgium, UK Sweden are eligible if they have a >10.0% expected developing multiple as determined by score or family...
Platelet-rich fibrin (PRF), derived from human blood, rich in wound healing components, has drawbacks direct injections, such as rapid matrix degradation and growth factor release. Marine polysaccharides, mimicking the extracellular matrix, show promising potential tissue engineering. In this study, we impregnated self-assembled fucoidan/chitosan (FU_CS) hydrogels with PRF obtaining PRF/FU_CS hydrogels. Our objective was to analyze properties of a hydrogel sustained release factors that...
Summary Background In many Demodex-associated skin diseases Demodex mites are present in abundance and seem to be at least partially pathogenic. So far all diagnostic approaches such as scraping or standardized superficial biopsy (semi-)invasive may cause discomfort the patient. Objectives To see whether confocal laser scanning microscopy (CLSM) – a noninvasive method for visualization of layers is able detect quantify D. folliculorum facial patients with rosacea. Methods Twenty-five (34–72...
Patients with permanent end ileostomy are at high risk for detrimental stomal effects on their quality of life. However, little is known about the long-term life these patients.The purpose this study was to assess in patients ileostomy.Registration German self-help organization ILCO used study.Selection included a cross-sectional survey 1434 ileostomy.Quality assessed using Medical Outcomes Study Short Form 36, including physical and mental component summary scores, Gastrointestinal Quality...
Demodex mites seem to serve as a pathogenic trigger in many Demodex-associated diseases such rosacea. In facial skin of patients with rosacea significantly higher numbers have been shown compared healthy controls. Reflectance confocal microscopy (RCM) allows the detection and quantification vivo noninvasively. It is hypothesized that reduction under therapy can be monitored by RCM.To use RCM monitor density before after treatment.In 25 was performed therapy. Mosaics 5 × mm(2) 8 were scanned,...