A5100644008- Carcinogens and Genotoxicity Assessment
- Environmental Toxicology and Ecotoxicology
- Mercury impact and mitigation studies
- Microplastics and Plastic Pollution
- bioluminescence and chemiluminescence research
- Skin Protection and Aging
- Aquatic Ecosystems and Phytoplankton Dynamics
- Selenium in Biological Systems
- Marine Toxins and Detection Methods
- Gene expression and cancer classification
- Marine and coastal ecosystems
- Effects and risks of endocrine disrupting chemicals
- Biochemical Analysis and Sensing Techniques
- Seaweed-derived Bioactive Compounds
- melanin and skin pigmentation
- Neurological Disease Mechanisms and Treatments
- Heavy Metal Exposure and Toxicity
- Marine and coastal plant biology
- biodegradable polymer synthesis and properties
- Nanoparticles: synthesis and applications
- Genomics, phytochemicals, and oxidative stress
- Marine Biology and Environmental Chemistry
- Neurological Disorders and Treatments
- Flavonoids in Medical Research
- Phytochemicals and Antioxidant Activities
Incheon National University
2016-2025
Kyung Hee University
2008-2024
Korea University
2020
Incheon Medical Center
2017
Government of the Republic of Korea
2017
Eulji University
2012-2013
Korea Institute of Science and Technology
1999-2010
Weatherford College
2009
The island-like distribution of the oxygen functional groups graphene oxide was identified by deposition TiO<sub>2</sub> on surface using low-temperature atomic layer deposition.
Antifouling biocides such as organotin compounds and their alternatives are potent toxicants in marine ecosystems. In this study, we employed several molecular biochemical response systems of the Pacific oyster Crassostrea gigas to understand a potential mode action antifouling (i.e. tributyltin (TBT), diuron irgarol) after exposure different concentrations (0.01, 0.1, 1 μg L-1) for 96 h. As result, all three strongly induced antioxidant defense system. TBT reduced both enzymatic activity...
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Although blue light has been reported to affect skin cells negatively, little is known about its action mechanisms in cells. Therefore, we investigated the role of transient receptor potential vanilloid 1 (TRPV1) light-induced effects on human keratinocytes and underlying mechanisms. Blue decreased cell proliferation upregulated TRPV1 expression. also suppressed epidermal growth factor receptor- (EGFR-) mediated signaling pathway by reducing protein levels EGFR suppressing...
Plastics pose a significant threat to marine ecosystems, owing their slow biodegradability. Microplastics (MPs), in particular, affect life and maricultural organisms can enter the food chain via ingestion by organisms, leading bioaccumulation predators, including humans. This study assessed toxic interactions between polystyrene microplastic particles (PSMPs) cadmium (Cd) phenanthrene (Phe) using bivalves. While PSMPs were non-toxic Pacific oysters (Crassostrea gigas), toxicity of Cd Phe...
Pyropia yezoensis, a red alga, is popular and harvested lot in East Asia famous for its medicinal properties attributable to bioactive compounds including amino acids (porphyra-334 shinorine, etc.), polysaccharides, phytosterols, pigments, but anti-inflammatory effect mechanism of anti-atopic dermatitis (AD) have not been elucidated. In this study, we investigate the anti-AD P. yezoensis extract (PYE) on mRNA protein levels pro-inflammatory chemokines, thymus, activation-regulated chemokine...
Oligomeric proanthocyanidins (OPC), natural polyphenolic compounds found in plants, are known to have antioxidant and anti-cancer effects. We investigated whether the effects of OPC induced by apoptosis on human colorectal cancer cell line, SNU-C4.Colorectal SNU-C4 was cultured RPMI 1640 medium supplemented with 10% fetal bovine serum. The cytotoxic effect assessed 3-(4, 5-dimethylthiazol-2-yl)-2, 5-diphenylt-etrazolium bromide (MTT) assay. To find out apoptotic death, 4,...
Phospholipidosis (PL), a disorder characterized by an accumulation of phospholipids in lysosome-derived multilamellar vesicles owing to abnormal lipid metabolism. Amiodarone (AM), antiarrhythmic drug, can induce pulmonary PL. First, evaluate potential mechanisms phospholipidosis, we found metabolism-–related genes microarray. PPARG, FADS2, and SCD out these were key metabolism PPAR signaling AM. The messenger RNA (mRNA) levels upregulated PPARγ antagonist GW9662 was used investigate the...
The prevalence of vascular dementia continues to increase with no cure. Thus, it is important identify the aggravating factors delay disease progression in patients. Obesity a well-known risk factor for and causes mild cognitive impairment. In present study, we evaluated whether obesity exacerbates impairment rats how affects synaptic plasticity through BDNF pathway. We randomly assigned 30 Wistar male three groups: sham surgery (Sham), (VaD), (OB + VaD). fed 60% high-fat diet establish...