A5013913004- Characterization and Applications of Magnetic Nanoparticles
- Advanced biosensing and bioanalysis techniques
- Lipid Membrane Structure and Behavior
- Microfluidic and Bio-sensing Technologies
- Biosensors and Analytical Detection
- Metal-Organic Frameworks: Synthesis and Applications
- Geomagnetism and Paleomagnetism Studies
- Lignin and Wood Chemistry
- Alzheimer's disease research and treatments
- Magnetic properties of thin films
- SARS-CoV-2 detection and testing
- Microfluidic and Capillary Electrophoresis Applications
- Cellular transport and secretion
- Protein Structure and Dynamics
- Autonomous Vehicle Technology and Safety
- Innovative Microfluidic and Catalytic Techniques Innovation
- RNA Interference and Gene Delivery
- ZnO doping and properties
- Heme Oxygenase-1 and Carbon Monoxide
- Neuroscience and Neural Engineering
- Hemoglobin structure and function
- Iron oxide chemistry and applications
- Ferroelectric and Negative Capacitance Devices
- Minerals Flotation and Separation Techniques
- Influenza Virus Research Studies
University of Minnesota
2016-2025
Hubei University of Technology
2024-2025
Sinochem Group (China)
2024
Shenyang Sinochem Agrochemicals R&D Co., Ltd. (China)
2024
Zhejiang University
2024
University of California, Irvine
2020-2022
Bohai University
2018-2021
Jinzhou Central Hospital
2020-2021
Boehringer Ingelheim (United States)
2021
Hebei University of Engineering
2019-2021
To achieve a rapid and facile quantitative evaluation of Sudan I illegally added in ketchup, fluorescent carbon quantum dots with excellent stability acidic environments are required as the actual pH value ketchup is close to 4.0.
Abstract In the past decade, there has been a significant rise in development of novel spintronic device architectures specifically designed to meet demands diverse biomedical applications. These advancements have notably focused on enhancing various bioassay detection techniques, including magnetocardiography and neural signal recording. Through collaboration within spintronics community, these devices are rapidly transitioning from laboratory prototypes practical applications, catering...
Articular cartilage has poor capability for repair following trauma or degenerative pathology due to avascular property, low cell density and migratory ability. Discovery of novel therapeutic approaches articular remains a significant clinical need. Hypoxia is hallmark development pathology. inducible factor-1alpha (HIF-1α) been identified as key mediator chondrocytes response fluctuations oxygen availability during repair. This suggests that HIF-1α may serve target modulating chondrocyte...
With the ongoing global pandemic of coronavirus disease 2019 (COVID-19), there is an increasing quest for more accessible, easy-to-use, rapid, inexpensive, and high-accuracy diagnostic tools. Traditional methods such as qRT-PCR (quantitative reverse transcription-PCR) ELISA (enzyme-linked immunosorbent assay) require multiple steps, trained technicians, long turnaround time that may worsen surveillance control. In sight this situation, a one-step, platform will be valuable future epidemic...
Magnetic nanoparticles (MNPs) have unique physical and chemical properties, such as high surface area to volume ratio size-related magnetism, which are completely different from their bulk materials. Benefiting the facile synthesis modification strategies, MNPs been widely studied for applications in nanomedicine. Herein, we firstly summarized designs of perspectives materials physicochemical properties tailored biomedical applications. particle spectroscopy (MPS), first reported 2006, has...
The presence of lignin in biomass constitutes a substantial obstacle to the efficient production sugar platforms via enzymatic hydrolysis. Current research mainly focuses on interactions based chemical structures lignin, while influence its particles morphology has been largely overlooked. In this study, two fractions (F1 and F2) were obtained by extraction with ethyl acetate petroleum ether sequence. Lignin characterization, cellulase hydrolysis investigation, computer simulation evaluation...
Abstract Magnetic particle imaging (MPI) is a tracer-based tomographic technique utilized in applications such as lung perfusion imaging, cancer diagnosis, stem cell tracking, etc. The goal of translating MPI to clinical use has prompted studies on further improving the spatial-temporal resolutions through various methods, including image reconstruction algorithm, scanning trajectory design, magnetic field profile and tracer design. Iron oxide nanoparticles (MNPs) are favored for resonance...
The ∼25 N-terminal "HAfp" residues of the HA2 subunit influenza virus hemagglutinin protein are critical for fusion between viral and endosomal membranes at low pH. Earlier studies HAfp in detergent support (1) N-helix/turn/C-helix structure pH 5 with open interhelical geometry N-helix/turn/C-coil 7; or (2) both pHs closed geometry. These different structures led to very models membrane location catalysis by HAfp. In this study, membrane-associated is probed solid-state NMR. data well-fitted...
Abstract Magnetic particle spectroscopy (MPS) is an emerging biosensing technique that detects target analytes by exploiting the dynamic magnetic responses of nanoparticles (MNPs). Due to ease synthesis and surface chemical functionalization MNPs, MPS-based bioassays have gained popularity around globe. One limiting factor for assay ability detect multiple simultaneously in a single run, namely, multiplexed bioassay. Several groups reported realization on surface-based MPS platforms...
Chymase plays an important and diverse role in the homeostasis of a number cardiovascular processes. Herein, we describe identification potent, selective chymase inhibitors, developed using fragment-based, structure-guided linking optimization techniques. High-concentration biophysical screening methods followed by high-throughput crystallography identified oxindole fragment bound to S1 pocket protein exhibiting novel interaction pattern hitherto not observed inhibitors. X-ray...
In urban areas, variations in the functional usage of buildings or their clusters directly influence 2D/3D morphology which can lead to changes ventilation potential (VP) at different heights, but there is a lack refined quantitative relationship analysis between 3D building form parameters (BFPs) and VP heights within certain area. The objective our study obtain simulated wind field data from considering distances roads, transverse longitudinal sections. We employ partial correlation...
In recent years, magnetic particle spectroscopy (MPS) has become a highly sensitive and versatile sensing technique for quantitative bioassays. It relies on the dynamic responses of nanoparticles (MNPs) detection target analytes in liquid phase. There are many research studies reporting application MPS detecting variety including viruses, toxins, nucleic acids, so forth. Herein, we report modified version platform with addition one-stage lock-in design to remove feedthrough signals induced...