- Radiation Therapy and Dosimetry
- Advanced Radiotherapy Techniques
- Radiation Detection and Scintillator Technologies
- Medical Imaging Techniques and Applications
- Radiation Effects in Electronics
- Advanced X-ray and CT Imaging
- Radiation Effects and Dosimetry
- Advanced NMR Techniques and Applications
- Nuclear Physics and Applications
- Radiation Dose and Imaging
- Advanced Chemical Physics Studies
- Atomic and Subatomic Physics Research
- Electron Spin Resonance Studies
- Solid-state spectroscopy and crystallography
- Boron Compounds in Chemistry
- Lung Cancer Diagnosis and Treatment
- Hemoglobin structure and function
- Effects of Radiation Exposure
- Muon and positron interactions and applications
- Prostate Cancer Treatment and Research
- Prostate Cancer Diagnosis and Treatment
- Head and Neck Cancer Studies
- Cancer Immunotherapy and Biomarkers
- Nanoplatforms for cancer theranostics
- Glioma Diagnosis and Treatment
The University of Texas MD Anderson Cancer Center
2015-2024
ICAR - Central Island Agricultural Research Institute
2020
Banaras Hindu University
2020
Odisha University of Agriculture and Technology
2020
John Wiley & Sons (United States)
2019
Swedish Medical Center
2019
University of Wisconsin System
2019
American Association of Physicists in Medicine
2019
Ashland (United States)
2019
UPMC Health System
2019
Task Group (TG) 224 was established by the American Association of Physicists in Medicine's Science Council under Radiation Therapy Committee and Work on Particle Beams. The group charged with developing comprehensive quality assurance (QA) guidelines recommendations for three commonly employed proton therapy techniques beam delivery: scattering, uniform scanning, pencil scanning. This report supplements QA machine performance other widely used modalities, such as photons electrons (TG 142,...
Partial discharge (PD) detection, measurement and classification constitute an important tool for quality assessment of insulation systems utilized in HV power apparatus cables. The patterns obtained with PD detectors contain characteristic features the source/class respective partial process involved. recognition source from data represents stage. Usually, this stage consists a two-step procedure, i.e., extraction feature vector followed by classification/recognition corresponding source....
Purpose To describe a summary of the clinical commissioning discrete spot scanning proton beam at Proton Therapy Center, Houston (PTC‐H). Methods Discrete system is composed delivery (Hitachi ProBeat), an electronic medical record (Mosaiq V 1.5), and treatment planning (TPS) (Eclipse 8.1). pencil beams (spots) are used to deposit dose by layer for distal ranges spanning from over maximum scan area isocenter . An arbitrarily chosen reference calibration condition has been selected define...
Since the Gafchromic film EBT has been recently replaced by newer model EBT2, its characterization, especially energy dependence, become critically important. The dependence of dose response EBT2 is evaluated for a broad range energies from different radiation sources used in therapy.The beams this study comprised kilovoltage x rays (75, 125, and 250 kVp), 137Cs gamma (662 KeV), 60Co (1.17-1.33 MeV), megavoltage (6 18 MV), electron 20 proton (100 MeV). film's to each above was measured over...
Purpose: To assess the dosimetric impact of interplay between spot‐scanning proton beam and respiratory motion in intensity‐modulated therapy (IMPT) for stage III lung cancer. Methods: Eleven patients were sampled from 112 with nonsmall cell cancer to well represent distribution terms target size motion. Clinical volumes (CTVs) planning (PTVs) defined according authorsˈ clinical protocol. Uniform realistic breathing patterns considered along regular‐ hypofractionation scenarios. The dose...
Purpose: Optically stimulated luminescent detectors (OSLDs) are quickly gaining popularity as passive dosimeters, with applications in medicine for linac output calibration verification, brachytherapy source treatment plan quality assurance, and clinical dose measurements. With such wide applications, these dosimeters must be characterized numerous factors affecting their response. The most abundant commercial OSLD is the InLight/OSL system from Landauer, Inc. purpose of this study was to...
Purpose: To present our method and experience in commissioning dose models water for spot scanning proton therapy a commercial treatment planning system (TPS). Methods: The input data required by the TPS included in‐air transverse profiles integral depth doses (IDDs). All were obtained from Monte Carlo (MC) simulations that had been validated measurements. MC‐generated IDDs converted to units of Gy mm 2 /MU using measured at cm employing largest commercially available parallel‐plate...
Active spot scanning proton therapy is becoming increasingly adopted by centers worldwide. Unlike passive-scattering therapy, active especially intensity-modulated requires proper modeling of each to ensure accurate computation the total dose distribution contributed from a large number spots. During commissioning gantry at Proton Therapy Center in Houston, it was observed that long-range scattering protons medium may have been inadequately modeled for high-energy beams commercial treatment...
The purpose of this work was to assess the monitor unit (MU) values and position accuracy spot scanning proton beams as recorded by daily treatment logs control system, furthermore establish feasibility using delivered positions MU calculate evaluate doses patients.To validate positions, authors generated executed a test plan containing nine which ten each. were measured with radiographic films Matrixx 2D ion-chambers array placed at isocenter plane compared for displacements from planned...
Abstract This paper summarizes clinical commissioning of the world's first commercial, clinically utilized installation a compact, image‐guided, pencil‐beam scanning, intensity‐modulated proton therapy system, IBA Proteus ® ONE , at Willis‐Knighton Cancer Center ( WKCC ) in Shreveport, LA . The is single‐room, compact‐gantry system employing cyclotron‐generated beam with image guidance via cone‐beam CT as well stereoscopic orthogonal and oblique planar kV imaging. Coupling 220° gantry...
Plastic scintillation detectors (PSDs) have many advantages over other in small field dosimetry due to their high spatial resolution, excellent water equivalence and instantaneous readout. However, proton beams, the PSDs undergo a quenching effect which makes signal level reduced significantly when detector is close Bragg peak where linear energy transfer (LET) for protons very high. This study measures correction factor (QCF) PSD clinical passive-scattering beams investigates feasibility of...
Purpose: To develop methods for evaluation and mitigation of dosimetric impact due to respiratory diaphragmatic motion during free breathing in treatment distal esophageal cancers using intensity‐modulated proton therapy (IMPT). Methods: This was a retrospective study on 11 patients with cancer. For each patient, four‐dimensional computed tomography (4D CT) data were acquired, nominal dose calculated the average phase 4D CT. The changes water equivalent thickness (ΔWET) cover volume from...
Purpose: To investigate the effect of monitor unit (MU) constraints on dose distribution created by intensity modulated proton therapy (IMPT) treatment planning using single‐field optimization (SFO). Methods: Ninety‐four energies between 72.5 and 221.8 MeV are available for scanning beam IMPT delivery at our institution. The minimum maximum MUs delivering each pencil (spot) 0.005 0.04, respectively. These MU not considered during system; spots converted to deliverable postprocessing....
In this study, the authors investigated feasibility of using a 3D liquid scintillator (LS) detector system for verification and characterization proton beams in real time intensity energy‐modulated therapy. A plastic tank filled with was irradiated pristine Bragg peaks. Scintillation light produced during irradiation measured CCD camera. Acquisition rates 20 10 frames per second (fps) were used to image consecutive frame sequences. These measurements then compared ion chamber Monte Carlo...