- Liver Disease Diagnosis and Treatment
- Liver Disease and Transplantation
- Hepatitis C virus research
- Gastrointestinal Bleeding Diagnosis and Treatment
- Organ Transplantation Techniques and Outcomes
- Gastrointestinal disorders and treatments
- Helicobacter pylori-related gastroenterology studies
- Cystic Fibrosis Research Advances
- Immunodeficiency and Autoimmune Disorders
- Esophageal and GI Pathology
- Eosinophilic Esophagitis
- Pancreatitis Pathology and Treatment
- Pancreatic and Hepatic Oncology Research
- Inflammatory Bowel Disease
- Gastroesophageal reflux and treatments
- Liver Diseases and Immunity
- Diverticular Disease and Complications
- Anorectal Disease Treatments and Outcomes
- Pericarditis and Cardiac Tamponade
- Diabetes Management and Education
- Child Nutrition and Feeding Issues
- Child and Adolescent Health
- Ovarian cancer diagnosis and treatment
- Vascular Tumors and Angiosarcomas
- Adrenal Hormones and Disorders
University of Minnesota
2020-2025
University of Minnesota Medical Center
2024
University of Michigan
2015-2019
A. Alfred Taubman Health Care Center
2019
Michigan Medicine
2016-2017
Michigan United
2017
Center Point
2012
Sheffield Children's Hospital
2009
Sheffield Children's NHS Foundation Trust
2007
The Royal Free Hospital
2000-2004
Intestinal pathology, i.e., ileocolonic lymphoid nodular hyperplasia (LNH) and mucosal inflammation, has been described in children with developmental disorders. This study describes some of the endoscopic pathological characteristics a group disorders (affected children) that are associated behavioral regression bowel symptoms, compares them pediatric controls.Ileocolonoscopy biopsy were performed on 60 affected (median age 6 yr, range 3-16; 53 male). Developmental diagnoses autism (50...
Despite effective treatment for chronic hepatitis C, deficiencies in diagnosis and access to care preclude disease elimination. Screening of baby boomers remains low. The aims this study were assess the impact an electronic health record–based prompt on C virus (HCV) screening rates primary specialty among those newly diagnosed. We implemented “best practice advisory” (BPA) that prompted providers perform HCV patients seen clinic (1) born between 1945 1965, (2) who lacked a prior infection,...
Objective: To systematically evaluate the feasibility and methodology to carry out wireless capsule endoscopy (WCE) in children <8 years define small intestinal pathology. Design: Prospective European multicentre study with negative prior investigation. Patients interventions: 83 aged 1.5–7.9 were recruited. Initially, all offered “swallowing” (Group 1) for introduction. If this failed endoscopic placement 2) was used Roth net, Advance or custom-made introducers compared. Outcome measures:...
Patients with nonalcoholic fatty liver disease (NAFLD) are at an increased risk of cardiovascular disease. Hydoxy-3-methyglutaryl-coenzyme reductase inhibitors, statins, reduce the events.1Taylor F. Huffman M.D. Macedo A.F. et al.Statins for primary prevention disease.Cochrane Database Syst Rev. 2013; 1: CD004816Crossref PubMed Scopus (604) Google Scholar Studies have shown that statins safe among patients disease, including those compensated cirrhosis,2Lewis J.H. Mortensen M.E. Zweig S....
Meigs syndrome is a rare phenomenon seen in approximately 1% of patients diagnosed with ovarian tumours. It defined as triad benign tumour, pleural effusion and ascites complete resolution symptoms following surgical intervention. This constellation findings can be confused several diagnoses, ranging from metastatic cancer to decompensated cirrhosis. Herein, we present young woman presenting new ascites, initially thought due cirrhotic portal hypertension found have an atypical presentation...
Background and Aims Patients with decompensated cirrhosis are prescribed numerous medications. Data limited as to whether patients receiving medications they need avoiding those do not. We examined a large national claims database (2010‐2015) characterize the complete medication profile well factors associated appropriate potentially inappropriate use in 12,621 cirrhosis. Approach Results Clinical guidelines existing literature were used determine The total days’ supply was calculated from...
The accumulation of 99mTc-technetium-labelled liposomes in abscesses was studied. Abscesses were produced the thighs albino rats by intramuscular injection Staphylococcus aureus. After 4 days these used to determine localisation anionic, cationic and neutral abscess area. This achieved radionuclide images a gamma camera an associated data-processing system. There pronounced uptake anionic area compared with corresponding unaffected thigh. Similar not shown liposomes. Abscess maximal at or...
Objective Assessing risk of adverse outcomes among patients with chronic liver disease has been challenging due to non-linear progression. We previously developed accurate prediction models for fibrosis progression and clinical advanced hepatitis C (CHC). The primary aim this study was validate a heterogeneous patient cohort. Design Adults CHC ≥3 years follow-up without hepatic decompensation, hepatocellular carcinoma (HCC), transplant (LT), HBV or HIV co-infection at presentation were...
Summary Background Patients with cirrhosis are at increased risk for osteoporosis, and those who suffer a fracture high mortality. Despite this, osteoporosis is often overlooked undertreated. This study aimed to evaluate screening, management, adverse medication events in patients cirrhosis. Methods We performed retrospective chart review of adult outpatients compensated decompensated seen single health system over 6‐year period. Patient demographics, liver bone comorbidities, DEXA scan...
Objective The incidence of alcohol-associated liver disease (ALD) is increasing, and weight loss surgery more common due to the obesity epidemic. Roux-en-Y gastric bypass (RYGB) associated with alcohol use disorder ALD; however, its impact on outcomes in patients hospitalised for hepatitis (AH) unclear. Design We performed a single-centre, retrospective study AH from June 2011 December 2019. Primary exposure was presence RYGB. primary outcome inpatient mortality. Secondary included overall...
1Division of Gastroenterology and Hepatology, University Michigan, Ann Arbor, MI, USA. 2Institute for Healthcare Policy Innovation, 3Veterans Affairs Hospital, Correspondence: A.S.L. (email: [email protected]) Published online 9 March 2018
We evaluated three acid-resistant pancreatic enzyme preparations by in vitro assays, and comparing degree of steatorrhea, creatorrhea, fecal wet weight, stool energy losses a randomized crossover study patients with insufficient cystic fibrosis. Aims the were to assess (a) most practicable reliable indicator malabsorption; (b) variation batch potency; (c) decline potency prolonged shelf life; (d) relative bioefficacy different preparations. In vivo study, absorption energy, nitrogen, fat did...
A 60-year-old man with clinically significant coexisting cardiac conditions presented chest pain. Shortly after his initial admission, he suddenly collapsed. Scans showed air in left ventricle.