Huan Liu

ORCID: 0000-0003-1508-9135
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Research Areas
  • Animal Virus Infections Studies
  • Viral gastroenteritis research and epidemiology
  • Sulfur-Based Synthesis Techniques
  • Plant Virus Research Studies
  • Virus-based gene therapy research
  • Organoselenium and organotellurium chemistry
  • Catalytic C–H Functionalization Methods
  • Cancer Diagnosis and Treatment
  • Plant and Fungal Interactions Research
  • SARS-CoV-2 detection and testing
  • Plant Pathogenic Bacteria Studies
  • Herpesvirus Infections and Treatments
  • Healthcare Systems and Challenges
  • Cancer therapeutics and mechanisms
  • Phytoplasmas and Hemiptera pathogens
  • Membrane Separation Technologies
  • Science, Research, and Medicine
  • Domain Adaptation and Few-Shot Learning
  • Adversarial Robustness in Machine Learning
  • COVID-19 diagnosis using AI
  • Viral Infections and Immunology Research
  • Bacillus and Francisella bacterial research
  • Glycosylation and Glycoproteins Research
  • Genomics, phytochemicals, and oxidative stress
  • Healthcare Systems and Public Health

Changchun University of Chinese Medicine
2024

Guangxi University of Chinese Medicine
2018-2023

Guangxi University
2018-2023

Soochow University
2017-2023

Capital Medical University
2022

Xi'an University of Architecture and Technology
2022

Wuhan Institute of Virology
2021-2022

Chinese Academy of Sciences
2021-2022

University of Chinese Academy of Sciences
2021-2022

Zhongnan Hospital of Wuhan University
2021

A novel and efficient approach for the selenium functionalization of indoles was developed with powder as source, catalyzed by 2,2,6,6-tetramethylpiperidinooxy (TEMPO) employing O2 green oxidant. This protocol provides a practical route synthesis 3-selenylindole derivatives has advantages readily available starting materials, mild reaction conditions, wide scope substrates. Electron spin-resonance (ESR) studies reveal that involves formation nitrogen-centered radicals via oxidation in situ...

10.1021/acs.orglett.7b03783 article EN Organic Letters 2018-02-02

Plumbagin (5-hydroxy-2-methyl-1,4-naphthoquinone, PLB), a naturally occurring naphthoquinone mainly isolated from the plant Plumbago zeylanica L., has been proven to possess anticancer activities towards multiple types of cancer. Although there an increasing amount research regarding its effects, association between oxidative stress, genotoxicity and cell cycle arrest induced by PLB still remains unclear. Therefore, it is important investigate their potential connections involvement DNA...

10.3390/ijms24076279 article EN International Journal of Molecular Sciences 2023-03-27

Astroviral infection is considered to be one of the causes mammalian diarrheal diseases. It has been shown that astrovirus infections cause varying degrees diarrhea in turkeys and mice. However, pathogenesis porcine unknown. In this study, virulence a cytopathic (PAstV) strain (PAstV1-GX1) isolated from PK-15 cell line was tested using seven-day-old nursing piglets. The results showed PAstV1-GX1 could mild diarrhea, growth retardation, damage villi small intestinal mucosa. all above symptoms...

10.3390/v11121156 article EN cc-by Viruses 2019-12-13

A novel and green multicomponent reaction in aqueous media is developed for the efficient synthesis of 1,3-selenazolines.

10.1039/d3gc00708a article EN Green Chemistry 2023-01-01

A low-protein diet supplemented with ketoacids (LPD + KA) maintains the nutritional status of patients chronic kidney disease (CKD). Oxidative damage and mitochondrial dysfunction associated upregulation p66SHC FoxO3a have been shown to contribute muscle atrophy. This study aimed determine whether LPD KA improves atrophy attenuates oxidative stress observed in CKD rats. 5/6 nephrectomy rats were randomly divided into three groups fed either 22% protein (normal-protein diet; NPD), 6%...

10.1186/s13395-018-0164-z article EN cc-by Skeletal Muscle 2018-05-31

A new and facile approach toward highly functionalized carbamimidoseleknoates was developed through the copper(I)-catalyzed ligand-promoted four-component reaction of isocyanides, selenium, amines, aryl iodides. The constructed a range organoselenium compounds containing an isoselenourea skeleton with potential bioactivity directly from selenium powder. simplicity method broad diversity substrates also highlight this work.

10.1021/acs.joc.7b01663 article EN The Journal of Organic Chemistry 2017-09-14

A new SARS-CoV-2 variant B.1.1.529 was named by the WHO as Omicron and classified a Variant of Concern (VOC) on 26 November 2021. Because this has more than 50 mutations, including 30 mutations spike, it generated lot concerns potential impacts VOC COVID-19. Here through ELISA assays using recombinant RBD proteins with sequences same to that WIV04 (lineage B.1), Delta coating antigens, binding capabilities between RBDs antibodies in COVID-19 convalescent sera vaccine after two doses...

10.3390/v14020335 article EN cc-by Viruses 2022-02-07

Porcine astroviruses (PAstVs) are prevalent in pigs worldwide, and five genotypes have been reported to circulate China. However, little is known about the coinfection status of PAstVs. For differential simultaneous diagnoses these PAstVs, a multiplex RT-PCR method was established on basis ORF2 gene type 1 PAstV, ORF1ab genes two This quintuple PCR system developed through optimization detection sensitivity specificity. The results showed that this could specifically detect all PAstV without...

10.3389/fvets.2021.684279 article EN cc-by Frontiers in Veterinary Science 2021-06-15

African Swine Fever Virus (ASFV), a lethal hemorrhagic fever of the swine, poses major threat to world’s swine population and has so far resulted in devastating socio-economic consequences. The situation is further compounded by lack an approved vaccine or antiviral drug. Herein, we investigated novel anti-ASFV approach targeting G-Quadruplexes (G4s) viral genome. Bioinformatics analysis putative G-quadruplex-forming sequences (PQSs) genome ASFV BA71V strain revealed 317 PQSs on forward...

10.3389/fmicb.2021.798431 article EN cc-by Frontiers in Microbiology 2021-12-16

Abstract Objective The purpose of this study was to investigate the prognostic value family history cancer (FHC) in predicting survival and clinicopathological features oral squamous cell carcinoma (OSCC) patients. Materials Methods This single‐institution utilized data from 610 patients undergoing surgery 2014 2020 that prospectively collected cataloged for research purposes. All underwent standard with/without radiotherapy or chemoradiotherapy. We statistically evaluated whether FHC...

10.1111/odi.14253 article EN Oral Diseases 2022-05-17

In recent years China has committed to energy saving and emission reduction. Chinese Government proposed a strategic policy of carbon neutrality. the context shortage, development sustainable cities green buildings is major trend. An important part consumption in consumed by temperature regulation buildings, reducing this can be great help cities. paper, our team propose scheme for with large permanent magnet direct drive fans system air conditioners. Compare conventional room which only...

10.1016/j.egyr.2023.04.222 article EN cc-by-nc-nd Energy Reports 2023-04-25

10.7544/issn1000-1239.2019.20190614 article EN Journal of Computer Research and Development 2019-12-01
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