Pehuén Fernández

ORCID: 0000-0003-1518-0377
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About
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Research Areas
  • Chronic Kidney Disease and Diabetes
  • Dialysis and Renal Disease Management
  • Renal Transplantation Outcomes and Treatments
  • Acute Kidney Injury Research
  • COVID-19 Clinical Research Studies
  • Hepatitis C virus research
  • Hepatitis B Virus Studies
  • Muscle and Compartmental Disorders
  • Cytomegalovirus and herpesvirus research
  • Cardiac, Anesthesia and Surgical Outcomes
  • Lysosomal Storage Disorders Research
  • Trypanosoma species research and implications
  • Diabetes Treatment and Management
  • Heparin-Induced Thrombocytopenia and Thrombosis
  • Abdominal Surgery and Complications
  • SARS-CoV-2 and COVID-19 Research
  • Transplantation: Methods and Outcomes
  • Hepatitis Viruses Studies and Epidemiology
  • Public Health and Environmental Issues
  • Organ Donation and Transplantation
  • Pneumocystis jirovecii pneumonia detection and treatment
  • COVID-19 and healthcare impacts
  • Biomedical Research and Pathophysiology
  • Liver Diseases and Immunity
  • Renal Diseases and Glomerulopathies

Hospital Privado
2017-2025

National University of Catamarca
2024

Universidad Católica de Córdoba
2014-2022

Institut de Virologie
2021

St James's University Hospital
2020

University of Leeds
2020

Hospital Universitario Fundación Jiménez Díaz
1993

Vitamin D status has been implicated in COVID-19 disease. The objective of the COVID-VIT-D trial was to investigate if an oral bolus cholecalciferol (100,000 IU) administered at hospital admission influences outcomes moderate-severe In same cohort, association between baseline serum calcidiol levels with also analysed.The is a multicentre, international, randomised, open label, clinical conducted throughout 1 year. Patients older than 18 years disease requiring hospitalisation were included....

10.1186/s12916-022-02290-8 article EN cc-by BMC Medicine 2022-02-18

Latin Americans are underrepresented in the current equations used to estimate glomerular filtration rate (GFR), and applicability of their predictions this population may therefore be questionable. The objective study was develop a new equation GFR based on data from Argentina. A cross-sectional conducted. We included 583 Argentinian adults development sample (DS) 78 temporary validation (TVS). Urinary iothalamate clearance (reference method), different predictive variables were candidate...

10.1038/s41598-025-90092-2 article EN cc-by-nc-nd Scientific Reports 2025-02-20

There is no consensus on the best equation to estimate glomerular filtration rate (eGFR) in obese patients (OP). Objective: evaluate performance of current equations and new Argentinian Equation (“AE”) GFR OP. Two validation samples were used: internal (IVS, using 10-fold cross-validation) temporary (TVS). OP whose was measured (mGFR) with clearance iothalamate between 2007/2017 n = 189) 2018/2019 (TVS, 26) included. To we bias (difference eGFR mGFR), P30 (percentage estimates within ±30%...

10.3390/nu15051233 article EN Nutrients 2023-02-28

Introducción: La enfermedad COVID-19 muestra una marcada heterogeneidad en su curso clínico, habiéndose descripto algunos factores que se asocian un peor pronóstico. El conocimiento del comportamiento de la el escenario local es gran relevancia para permitir mejor abordaje. 
 Métodos: Estudio retrospectivo dos hospitales ciudad Córdoba, Argentina, pacientes 18 años o más hospitalizados por infección activa SARS-CoV-2, desde marzo a octubre año 2020. Resultados: Se incluyeron 448...

10.31053/1853.0605.v78.n3.32518 article ES cc-by-nc Revista de la Facultad de Ciencias Médicas de Córdoba 2021-09-23

Introducción: Las infecciones del tracto urinario (ITU) constituyen la infección más frecuente en los trasplantados renales (TR). El objetivo principal fue determinar las características clínicas y microbiológicas de ITU que ocurren durante el primer año posterior al TR.
 Metodología: Estudio cohorte retrospectivo, donde se incluyeron pacientes mayores 18 años recibieron un TR entre 2009-2020 dos hospitales ciudad Córdoba. A través registro historias realizó seguimiento postrasplante...

10.31053/1853.0605.v80.n4.41244 article ES cc-by-nc Revista de la Facultad de Ciencias Médicas de Córdoba 2023-12-26

Fabry disease is a rare inherited lysosomal storage disorder caused by the deficiency of enzyme alpha-galactosidase A. There uncertainty regarding safety replacement therapy during pregnancy. We describe course and outcome seven pregnancies in six patients with who continued or reinitiated No adverse events, both mothers children, were observed.

10.1007/8904_2018_141 article EN JIMD Reports 2018-01-01

Urinary tract infections (UTI) are the most frequent infection in kidney transplant (KT) patients. The objectives of study were: to determine clinical and microbiological characteristics UTIs that occur during first year after KT, evaluate whether there was a change incidence extended-spectrum beta-lactamase (ESBL)-producing microorganisms between two time periods analyze possible risk factors for development UTI due multidrug-resistant (MRM).

10.1016/j.ekir.2024.02.954 article EN cc-by-nc-nd Kidney International Reports 2024-04-01

COVID-19 generated at least 700 million infections in the world. Among survivors, many have long-term cardiovascular, pulmonary, neurological, and cognitive sequelae. Acute kidney injury (AKI) associated with presents a complex physio-pathogenesis, affecting function through different mechanisms (including direct tissue viral invasion), producing tubulo-interstitial, glomerular and/or vascular damage. The incidence among hospitalized patients was 17% (although some series it up to 80%).

10.1016/j.ekir.2024.02.420 article EN cc-by-nc-nd Kidney International Reports 2024-04-01

The prevalence of Fabry Disease (FD) is estimated to range between 1:8,454 1:117,000 men. From large genetic screening programs in neonates, we know that the incidence FD-related mutations much more frequent, although these are not necessarily based on development subsequent clinical symptoms. "Classic" expressed 1:22,000 – 1:40,000 men and "late onset" 1:1,000-1:3,000 1:6,000-1:40,000 women.

10.1016/j.ekir.2024.02.304 article EN cc-by-nc-nd Kidney International Reports 2024-04-01

Estimar el filtrado glomerular (FG) en sujetos obesos es un desafío. Analizamos rendimiento de las fórmulas estimación esta población. Estudio corte transversal que incluyó a 100 con diversos grados obesidad, evaluados entre 2008 y 2015. Se midió FG iotalamato (patrón referencia) se estimó basadas creatinina sérica: Cockroft Gault, MDRD, CKD-EPI, MCQ CKD-MCQ (promedio estas). creó score performance global (S-P-Global) puntajes, para unificar todos los criterios análisis. En obesidad grado i...

10.1016/j.nefrol.2017.03.002 article ES Nefrología Latinoamericana 2017-04-01

A 53-year-old man had received a cadaver-donor renal transplant from donor with positive serology for Chagas disease.The patient high-dose immunosuppressive therapy due to two episodes of early acute allograft rejection.Three months after transplantation, he presented unexplained fever.Multiple Trypanosoma cruzi parasites were found in peripheral blood smear (photo and video), parasite load (by real-time PCR) above one million per milliliter was detected.Both benznidazole itraconazole...

10.1016/j.idcr.2017.09.001 article EN cc-by-nc-nd IDCases 2017-01-01
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