A5063297445- Silk-based biomaterials and applications
- Periodontal Regeneration and Treatments
- Electrospun Nanofibers in Biomedical Applications
- Hemostasis and retained surgical items
- Advanced Fiber Optic Sensors
- Photonic and Optical Devices
- Ocular Surface and Contact Lens
- Wound Healing and Treatments
- Corneal Surgery and Treatments
- Cellular Mechanics and Interactions
- 3D Printing in Biomedical Research
- Tissue Engineering and Regenerative Medicine
- Mechanical and Optical Resonators
- Cancer, Hypoxia, and Metabolism
- Corneal surgery and disorders
- Photodynamic Therapy Research Studies
- Neuroblastoma Research and Treatments
Northwestern University
2024
Illinois Institute of Technology
2018-2024
We have developed a novel type of 1550-nm Fiber Laser Microphone (FLM) based on miniature Distributed Bragg Reflector/Distributed Feedback (DBR/DFB) fiber lasers with graphene as diaphragms, i.e., the graphene-FLM. The graphene-FLM makes full use advantages high-efficiency a-few-cm-long DBR/DFB and ultra-sensitive diaphragm that is thin single atomic layer. first fabricated optimized parameters from modeling simulation Er/Yb co-doped lasers, using coupled modes theory solved by transfer...
Diabetic patients suffer from chronic wounds partly due to altered function of fibroblasts. Fibroblasts diabetic synthesize collagen I (COLI) at a much higher level than III (COLIII), resulting in delayed tissue granulation and, consequently, delay the overall wound healing process.We aimed revive matrix protein productivity fibroblasts by employing aligned, electrically conductive and biocompatible spider silk-CNT fibers as cell culture mediate electrical stimulation induce polarization...
Fibrillar collagen is a one-dimensional biopolymer and the most abundant structural protein in extracellular matrix (ECM) of connective tissues. Due to unique properties carbon nanotubes (CNTs), considerable attention has been given application CNTs developing biocomposite materials for tissue engineering drug delivery. When introduced tissues, inevitably interact integrate with impose discernible effect on cells vicinity. The positive collagen-CNT (COL-CNT) regeneration cytotoxicity free...
Electrospinning is a simple, low-cost, and highly efficient technique to generate desirable nano/microfibers from polymer solutions. Silk fibroin (SF), biopolymer found in Bombyx mori cocoons, has attracted attention for various biomedical applications. In this study, functionalized CNT was incorporated SF biocomposite fibers by electrospinning. The electrospun (E-spun) were well aligned with morphology mimicking the locally oriented ECM proteins connective tissues. While as-spun dissolved...
In response to corneal injury, an activation of epithelial stem cells and their direct progeny the early transit amplifying (eTA) rapidly proliferate is critical for proper re-epithelialization. Thus, it important understand how such stem/eTA cell regulated. Angiotensin-converting enzyme 2 (ACE2) predominantly expressed in stem/eTA-enriched limbal epithelium but its role was unclear. Single RNA sequencing (scRNA-seq) suggested that Ace2 involved proliferation cells. reduced following injury....
In trauma and surgery, efficient hemorrhage control is crucial to avert fatal blood loss increase the likelihood of survival. There a significant demand for novel biomaterials capable promptly effectively managing bleeding. This study aimed develop flexible biocomposite fibrous scaffolds with an electrospinning technique using silk fibroin (SF) indocyanine green (ICG). The FDA-approved ICG dye has unique photothermal properties. water permeability, degradability, biocompatibility Bombyx mori...