L Tobia

ORCID: 0000-0003-1532-932X
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About
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Research Areas
  • COVID-19 and Mental Health
  • Occupational Health and Safety Research
  • Musculoskeletal pain and rehabilitation
  • Occupational Health and Safety in Workplaces
  • Occupational health in dentistry
  • Quality and Safety in Healthcare
  • Healthcare professionals’ stress and burnout
  • Cancer and Skin Lesions
  • Biomedical Ethics and Regulation
  • Monoclonal and Polyclonal Antibodies Research
  • Chemical Safety and Risk Management
  • Long-Term Effects of COVID-19
  • Porphyrin Metabolism and Disorders
  • Acne and Rosacea Treatments and Effects
  • Migration, Health and Trauma
  • Fungal Plant Pathogen Control
  • Historical Medical Research and Treatments
  • Stress and Burnout Research
  • Wireless Body Area Networks
  • T-cell and B-cell Immunology
  • Sleep and Work-Related Fatigue
  • Inhalation and Respiratory Drug Delivery
  • Public health and occupational medicine
  • Soft tissue tumors and treatment
  • Electromagnetic Fields and Biological Effects

University of L'Aquila
2005-2025

Florida State University
2016

(1) Background: The objective was to investigate e-learning satisfaction in a sample of university students by evaluating quality life, stress sociality, and coping. (2) Methods: This an online survey involved 471 attending the University L'Aquila from June July 2021. primary goal estimating as measured E-learning Satisfaction Scale, while secondary outcomes were studying its relationship with demographic factors, perception stress, coping strategies using hierarchical regression model. (3)...

10.3390/ijerph19138214 article EN International Journal of Environmental Research and Public Health 2022-07-05

Safety in workplaces is a requirement for work sustainability. Construction workers are frequently exposed to dangerous airborne substances. While previous studies examined chemical risks other sectors, there limited research on occupational risk perception (OCRP) among construction workers. This study focuses evaluating OCRP and identifying its association with socio-demographic, occupational, training variables. In L’Aquila, Italy, sample of male involved post-earthquake reconstruction...

10.3390/su17083332 article EN Sustainability 2025-04-09

Background: Understanding healthcare providers' readiness and attitudes is crucial for integrating AI in healthcare, yet no validated tool exists to evaluate these aspects among Italian physicians. This study developed the Knowledge, Attitudes, Practice, Clinical Agreement between Medical Doctors Artificial Intelligence Questionnaire (I-KAPCAM-AI-Q). Methods: The validation process included expert review (n=18), face validity assessment (n=20), technical implementation testing, pilot testing...

10.1101/2025.04.11.25325592 preprint EN medRxiv (Cold Spring Harbor Laboratory) 2025-04-12

The pharmacokinetics (PK) of SB-240563 have been investigated after i.v. and s.c. administration to cynomolgus monkeys. Approximately linear PK was observed following over a 6000-fold dose range (0.05-300 mg/kg). After dosing, concentration declined in biexponential manner with mean terminal half-life 13 +/- 2 days. plasma clearance volume distribution at steady state were approximately 0.2 ml/h/kg 70 ml/kg, respectively. Following administration, completely absorbed into the systemic...

10.1016/s0022-3565(24)35210-3 article EN Journal of Pharmacology and Experimental Therapeutics 1999-12-01

Objective of the Study: This cross-sectional study examined perceived psychological well-being administrative/technical employees and researchers/lecturers at University L’Aquila (Italy) during COVID-19 pandemic. The was carried out in two different periods 2022: April 2022, when remote working still mandatory, December pandemic emergency had ended and, Italy, become voluntary for days a week exclusively administrative staff. Materials Methods: Perceived investigated using GHQ-12 (Global...

10.3390/ijerph21040403 article EN International Journal of Environmental Research and Public Health 2024-03-26

Pharmacists play a crucial role in the COVID-19 pandemic scenario, performing frontline roles for community, and supporting healthcare system. This study aimed at investigating stress its correlates among this category of workers high risk SARS-CoV-2 infection.The participants were employees "Municipal Pharmaceutical Company" L'Aquila (Italy). Data collected using an anonymous, web-based, self-administered questionnaire. Two independent surveys conducted, from June to July 2020, January...

10.1186/s40545-023-00523-6 article EN cc-by Journal of Pharmaceutical Policy and Practice 2023-01-27

Background SARS-CoV-2 and the consequent public health measures changed our habits, including prevention in oral health. Objectives The aim was to investigate relationship between perceived risk for infection preventive COVID-19 measures, general attitudes oral-hygiene habits. Materials Methods Data were collected via a web-based questionnaire, matched with medical history data obtained by Occupational Medicine Service. Descriptive statistics used analyze results of this observational...

10.2174/0118742106269156231220074711 article EN cc-by The Open Dentistry Journal 2024-01-10

The COVID-19 pandemic has led to unprecedented challenges globally, impacting various aspects of daily life, including education. This study examines the effects on stress levels and substance use among Italian medical students. Two independent surveys were conducted: 388 students interviewed before epidemic, 222 a year after epidemic began. Results revealed significant changes in levels, with reduction mild an increase severe during post-pandemic period, rising from 23% (95% CI: 19%-28%)...

10.21926/obm.neurobiol.2403237 article EN OBM Neurobiology 2024-08-06

Keliximab and clenoliximab are monkey/human chimeric CD4 monoclonal antibodies (mAbs) of the IgG1 IgG4 isotypes, respectively. The pharmacokinetics (PK) pharmacodynamics (PD) these mAbs were evaluated in transgenic mice bearing human molecules on their T cells after a single i.v. administration at three dose levels (5-125 mg/kg). PK keliximab similar, dose-dependent, adequately described by two-compartment model with saturable elimination from both compartments. enumeration circulating...

10.1016/s0022-3565(24)39200-6 article EN Journal of Pharmacology and Experimental Therapeutics 2000-04-01

The city of L'Aquila (central Italy) was hit by a strong earthquake in 2009 that caused the collapse several buildings, deaths and injured people. In following years, great number building sites were activated, workers resulted intensely exposed represent relevant target for research on environmental mutagenesis epidemiological surveillance. Cells buccal mucosa are considered an appropriate site early detecting cytogenetic damage, since it represents first barrier inhalation or ingestion can...

10.1016/j.ecoenv.2020.110989 article EN cc-by-nc-nd Ecotoxicology and Environmental Safety 2020-07-18

The aim was to estimate the perceived quality of life and its relationship with sociodemographic professional factors, perception susceptibility COVID-19, stress.It a longitudinal study.Professionals, working in Italian centers for pediatric neurocognitive, speech, psychomotor rehabilitation.Participants were interviewed online twice during COVID-19 outbreak Italy. questionnaire included: (i) measures health-related perform Summary Index Unhealthy Days, (ii) modified items from "Standard on...

10.3390/clinpract11040101 article EN cc-by Clinics and Practice 2021-11-15

This prospective study aimed to assess the physical and psychological health of construction workers examine relationship between their well-being preventive measures implemented against SARS-CoV-2.

10.1097/jom.0000000000003031 article EN cc-by-nc-nd Journal of Occupational and Environmental Medicine 2023-12-19

We evaluated the efficacy of a booster dose HBV in Italian medical students. conducted prospective observational study students who had received full course anti-HBV vaccination for at least 15 y. Those with an anti-HBs titer <10 mIU/mL were offered vaccine and antibody was reevaluated after 1 month. The participants classified into three categories: >100 mIU/mL, between 10 100 mIU/mL. population n. 625 student 355 (56.8%) anti HBs dose. A total 166 them 92.77% (38 + 116/166) achieved ≥10...

10.1080/21645515.2024.2439049 article EN cc-by-nc Human Vaccines & Immunotherapeutics 2024-12-18

Abstract. To implement the protocol contrasting diffusion of Covid-19, employer is required, to ensure safety and health worker at work, adopt measures related control body temperature (with respect for privacy), minimum distance during work all other activities such as breaks, canteen access toilets, in addition adoption specifically developed procedures, e.g. use man-down detection devices. In this context, project aims illustrate a system able providing support safeguarding workers' on...

10.5194/isprs-archives-xlvi-4-w1-2021-63-2021 article EN cc-by ˜The œinternational archives of the photogrammetry, remote sensing and spatial information sciences/International archives of the photogrammetry, remote sensing and spatial information sciences 2021-09-03
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