A5064080672- Medicinal Plants and Bioactive Compounds
- Microbial Metabolites in Food Biotechnology
- Phytochemistry and Biological Activities
- Carbohydrate Chemistry and Synthesis
- Phytochemicals and Antioxidant Activities
- Wheat and Barley Genetics and Pathology
- Biochemical Acid Research Studies
- Phytochemical compounds biological activities
- Mycotoxins in Agriculture and Food
- Diet, Metabolism, and Disease
- Phytochemical and Pharmacological Studies
- Agriculture, Plant Science, Crop Management
- Enzyme Production and Characterization
- Genomics, phytochemicals, and oxidative stress
- Paraoxonase enzyme and polymorphisms
- Polysaccharides and Plant Cell Walls
- Geology and Environmental Impact Studies
- Glycosylation and Glycoproteins Research
- Botany and Plant Ecology Studies
- Biofuel production and bioconversion
- Advanced Glycation End Products research
- Lichen and fungal ecology
- Integrated Water Resources Management
- Flavonoids in Medical Research
- Enzyme Catalysis and Immobilization
Institute of Chemistry of the Slovak Academy of Sciences
2015-2025
Slovak Academy of Sciences
2015-2025
University of Life Sciences in Lublin
2012
University of Computer Sciences and Economics in Olsztyn
1989
Phenylethanoid glycosides (PhGs) are widely occurring secondary metabolites of medicinal plants with interesting biological activities such as antioxidant, anti-inflammatory, neuroprotective, antiviral, hepatoprotective, immunomodulatory, etc. They characterized by a structural core formed phenethyl alcohol, usually tyrosol or hydroxytyrosol, attached to β-D-glucopyranose via glycosidic bond. This is further decorated phenolic acids another saccharide. Several studies suggest an important...
Tyrosol β-d-fructofuranoside and hydroxytyrosol have been synthesized as new compounds in 27.6 19.5% respective yields through transfructosylation of tyrosol hydroxytyrosol. Yeast β-galactosidase Lactozym 3000 L comprising invertase activity was used catalyst. Besides the main monofructosides, an equimolar mixture β-d-fructofuranosyl-((2→1)-β-d-fructofuranoside β-d-fructofuranosyl-(2→6)-β-d-fructofuranoside isolated additional product fraction 14.3% yield.
Apiose is a branched pentose naturally occurring either as component of the plant cell wall polysaccharides or sugar moiety present in numerous secondary metabolites such flavonoid and phenylethanoid glycosides, substrates defense systems glycosylated aroma precursors. The enzymes catalyzing hydrolysis apiosylated substances (mainly glycosidases specific towards apiose acuminose) have promising applications not only (flavor development), but potentially also synthesis apiosides...
Natural products represent the source or inspiration for majority of active ingredients medicines because their structural diversity and a wide range biological effects. Our aims in this study were (i) to synthesize enzymatically salidroside (SAL), most effective phenylethanoid glycoside Rhodiola species; (ii) examine its antioxidant capacity using cell-free assays (reducing power, DPPH radicals scavenging Fe2+ -chelating assays); (iii) assess DNA-protective potential on plasmid DNA (DNA...
Abstract Tyrosol robinobioside was prepared under catalysis of robinobiosidase-containing seed meal from common buckthorn Rhamnus cathartica . Robinin, a flavonoid isolated the flowers black locust ( Robinia pseudoacacia ) served as robinobiosyl donor. The glycosylation proceeded predominantly on primary hydroxyl tyrosol, typically yielding mixtures isomeric glycosides in ratios 5:1 to 8:1 with overall yields robinobiosides higher than 20%. This is first robinobiosylation promoted enzymatic...
Tyrosol (T) and hydroxytyrosol (HOT) their glycosides are promising candidates for applications in functional food products or complementary therapy. A series of phenylethanoid glycofuranosides (PEGFs) were synthesized to compare some biochemical biological activities with T HOT. The optimization glycosylation promoted by environmentally benign basic zinc carbonate was performed prepare HOT α-L-arabino-, β-D-apio-, β-D-ribofuranosides. β-D-fructofuranosides, prepared enzymatic...
Abstract Tyrosol robinobioside was prepared under catalysis of robinobiosidase-containing seed meal from common buckthorn Rhamnus cathartica . Robinin, a flavonoid isolated the flowers black locust ( Robinia pseudoacacia ) served as donor robinobiose. The glycosylation proceeded predominantly on primary hydroxyl tyrosol, typically yielding mixtures isomeric glycosides in ratios 5:1 to 8:1 with overall yields robinobiosides higher than 20%. This is first robinobiosylation promoted enzymatic catalysis.