Objective. In 1991, we noted the emergence amongst our extremely low birth weight neonates of a new clinical entity, invasive fungal dermatitis, characterized by erosive, crusting lesions and high rate subsequent systemic infection. We sought to define this condition examine potential risk factors. Methods. Sixteen with dermatitis were seen during 2-year period in three Baylor College Medicine affiliated intensive care nurseries. Seven confirmed cases, skin biopsy evidence invasion beyond...

Objective. To identify areas of consensus and controversy in the management neonatal candidiasis. Methods. A questionnaire was distributed to US-based members Pediatric Infectious Diseases Society a sampling US neonatologists. Results. Three hundred eighty evaluable questionnaires were returned (42% those mailed). Ninety-five percent respondents have cared for an infant with systemic candidiasis past 2 years. Fluconazole liposomal amphotericin are used some extent by 90 69% respondents,...

BACKGROUND. Spontaneous intestinal perforation of the extremely low birth weight infant (≤1000 g) is associated with a high incidence Candida and coagulase-negative Staphylococcus sepsis. Little known about prenatal risk factors, histopathologic examination placentas in infants spontaneous has not been reported. OBJECTIVES. Our objective was to investigate maternal factors specific placental findings sample perforation. We compared clinical outcomes matched control group. PATIENTS AND...

Journal Article Group B Streptococci Elicit Leukotriene B4 and Interleukin-8 from Human Monocytes: Neonates Exhibit a Diminished Response Get access Judith L. Rowen, Rowen Section of Infectious Diseases Speros P. Martel Laboratory, Leukocyte Biology, Department Pediatrics, Baylor College Medicine, Houston, Texas Reprints or correspondence: Dr. Dept. Diseases, One Plaza, TX 77030. Search for other works by this author on: Oxford Academic PubMed Google Scholar C. Wayne Smith, Smith Morven S....

Systemic candidiasis affects 1.6 to 4.5% of very low birth weight (</= 1,500 g) infants. A specimen archive Candida strains from intensive care nurseries was created; it currently houses 98 isolates 17 institutions. Eight (8.2%) were misidentified at the referring institution. The MICs fluconazole for seven (7.1%, all non-C. albicans species, one initially) >8 microg/ml.

ROWEN, JUDITH L. MD; DOERR, CYNTHIA A. VOGEL, HANNES BAKER, CAROL J. MD Author Information

The mechanisms by which neutrophils migrate through the alveolar interstitium during acute lung inflammation are unknown. We wished to determine whether platelet-activating factor (PAF) and IL-8, two important mediators in neutrophil transendothelial migration, stimulated adherence motility on fibroblasts. Canine fibroblasts grown from explants were characterized light electron microscopy, flow cytometry. Unstimulated adhered poorly (less than 2%) cultured However, with PAF (20-200 nM)...

ROWEN, JUDITH L. MD; CORREA, ARMANDO G. SOKOL, DAWN M. HAWKINS, HAL K. PHD, LEVY, MOISE EDWARDS, MORVEN S. MD Author Information

Eosinophils produce oxidants and other toxic substances thus have the potential to cause acute lung injury. We found that addition of normal human eosinophils respiratory burst stimulant phorbol myristate acetate isolated perfused rat lungs caused edematous injury as reflected in weight gain morphologic changes. Lung body ratio (× 103) was 16.7 ± 3.3 experimental group with stimulated added compared 4.7 0.38 for control group. Morphologic examination showed both epithelial endothelial...

The organisms traditionally associated with early onset neonatal sepsis are group B streptococci, Escherichia coli and Listeria monocytogenes. As antepartum antibiotic use for prevention of streptococcal disease increases, it is likely that the recovered in may shift toward those resistant to ampicillin. We recently cared a neonate caused by ampicillin-resistant Morganella morganii; his mother had concomitant infection same pathogen. Early this organism has not been described previously....

Disasters happen in all communities and negatively impact the health safety of populations if not well managed. Rural organizations face greater challenges when implementing emergency preparedness policies need unique resources to help ensure their communities. The purpose this article is describe development evaluation an agricultural simulation scenario designed for rural organizations.The disaster was developed after determining desired content domains. Forty students from nursing,...

Infections in the neonate caused by vaginal commensal Gardnerella vaginalis are rare and mostly consist of bacteremia. A 4130-g term developed an infection a scalp hematoma with G. vaginalis. The association electronic fetal monitoring. only clinical sign was increase size hematoma.

Coagulase-negative staphylococci are a major cause of nosocomial infections in neonatal intensive care unit patients. These usually related to the presence intravascular devices. An 1175-g preterm neonate developed primary osteomyelitis and septic arthritis by coagulase-negative absence any indwelling central catheters.

Coagulase-negative staphylococci are a major cause of nosocomial infections in neonatal intensive care unit patients. These usually related to the presence intravascular devices. An 1175-g preterm neonate developed primary osteomyelitis and septic arthritis by coagulase-negative absence any indwelling central catheters. Osteomyelitis period is uncommon with relative incidence 1 3 per 1000 admissions units (NICU). Concomitant suppurative well-recognized complication facilitated transphysial...

Abstract Objective/Hypothesis Bordetella pertussis is an unusual cause of otitis media with effusion. We report a case in neonate. Study Design Case report. Methods A presented. Results 1‐month‐old infant girl was admitted because respiratory distress and subsequently found to have pertussis. On examination she noted middle ear Myringotomy performed for culture. Culture confirmed B . were unable find previous media. Conclusion has been identified the effusion syndrome.

Medical Education Program Highlights Engineering integration: Carle Illinois College of Medicine (CIMED), a public–private partnership between the University at Urbana–Champaign and Foundation, aims to graduate physician–innovators. As backbone this reenvisioned medical school, CIMED built engineering into every part its 4-year, 3-phase curriculum. In Phase 1 preclinical courses, concepts weave through weekly problem-based learning (PBL) cases Discovery Innovation (MEDI) laboratory sessions....