A5100735524- Nanocluster Synthesis and Applications
- Advanced Nanomaterials in Catalysis
- Gold and Silver Nanoparticles Synthesis and Applications
- Advanced biosensing and bioanalysis techniques
- Quantum Dots Synthesis And Properties
- Astrophysics and Cosmic Phenomena
- Carbon and Quantum Dots Applications
- Dark Matter and Cosmic Phenomena
- Nanoplatforms for cancer theranostics
- Nanoparticle-Based Drug Delivery
- Electrochemical sensors and biosensors
- Polymer Surface Interaction Studies
- Esophageal Cancer Research and Treatment
- Electrochemical Analysis and Applications
- Protein Interaction Studies and Fluorescence Analysis
- Luminescence and Fluorescent Materials
- Catalytic Processes in Materials Science
- Radio Astronomy Observations and Technology
- Photochromic and Fluorescence Chemistry
- Molecular Sensors and Ion Detection
- Graphene and Nanomaterials Applications
- Cancer-related gene regulation
- Conducting polymers and applications
- Angiogenesis and VEGF in Cancer
- Cosmology and Gravitation Theories
Northwestern Polytechnical University
2016-2025
The Fifth People’s Hospital of Suzhou
2025
Zhongyuan University of Technology
2025
Henan Academy of Sciences
2024-2025
Chinese Academy of Sciences
2012-2024
Jiangsu Second Normal University
2023-2024
Duke-NUS Medical School
2023-2024
University of Chinese Academy of Sciences
2015-2024
Southern University of Science and Technology
2016-2024
University of Science and Technology of China
2021-2024
The conformational changes of bovine serum albumin (BSA) in the albumin:gold nanoparticle bioconjugates were investigated detail by various spectroscopic techniques including UV−vis absorption, fluorescence, circular dichroism, and Fourier transform infrared spectroscopies. Our studies suggested that was prepared common adsorption method underwent substantial at both secondary tertiary structure levels. BSA found to adopt a more flexible state on boundary surface gold nanoparticles as result...
The “gold standard” for nanothermometry: application of ultrasmall, near-IR-emitting fluorescent gold nanoclusters (AuNCs) temperature sensing has been explored. AuNC-based nanothermometry features excellent thermal sensitivity and simultaneous imaging in HeLa cells. As a service to our authors readers, this journal provides supporting information supplied by the authors. Such materials are peer reviewed may be re-organized online delivery, but not copy-edited or typeset. Technical support...
Recent studies have firmly established that cellular uptake of nanoparticles is strongly affected by the presence and physicochemical properties a protein adsorption layer around these nanoparticles. Here, we modified human serum albumin (HSA), often used in model onto nanoparticles, to alter its surface charge distribution investigated consequences for corona formation small (radius ∼5 nm), dihydrolipoic acid-coated quantum dots (DHLA-QDs) using fluorescence correlation spectroscopy. HSA...
Abstract A facile strategy to synthesize water‐soluble fluorescent gold nanoclusters (Au NCs) stabilized with the bidentate ligand dihydrolipoic acid (DHLA) is reported. The DHLA‐capped Au NCs are characterized by UV–vis absorption spectroscopy, fluorescence transmission electron microscopy, and X‐ray photoelectron spectroscopy. possess many attractive features including ultrasmall size, bright near‐infrared luminescence, high colloidal stability, good biocompatibility, making them promising...
We report a new approach for the synthesis of fluorescent and water-soluble Ag nanoclusters, using common polyelectrolyte poly(methacrylic acid) as template.
In this work, a new type of ultrasmall Pt nanoclusters (Pt NCs) was prepared via facile one-pot approach by using yeast extract as the reductant and stabilizer. Besides their excellent water solubility, these extract-stabilized NCs also possess attractive peroxidase mimicking property. They can efficiently catalyze oxidation 3,3,5,5-tetramethylbenzidine (TMB) in coexistence hydrogen peroxide (H2O2). Catalytic mechanism analysis suggested that activity might originate from characteristic...
We report a facile strategy to synthesize water-soluble, fluorescent gold nanoclusters (AuNCs) in one step by using mild reductant, tetrakis(hydroxymethyl)phosphonium chloride (THPC). A zwitterionic functional ligand, D-penicillamine (DPA), as capping agent endowed the AuNCs with excellent stability aqueous solvent over physiologically relevant pH range. The DPA-capped displayed excitation and emission bands at 400 610 nm, respectively; fluorescence quantum yield was 1.3%. effect of...
A microwave-assisted strategy for synthesizing dihydrolipoic acid (DHLA) capped fluorescent gold nanoclusters (AuNCs) has been developed. Irradiation with microwaves during synthesis enhanced the fluorescence quantum yield (QY) of AuNCs by about five-fold and shortened reaction time from hours to several minutes. The as-synthesized DHLA-AuNCs possessed bright near-infrared (QY: 2.9%), ultrasmall hydrodynamic diameter (3.3 nm), good colloidal stability over physiologically relevant pH range...
Abstract Noble metal nanoparticles (NMNPs), which spring up like mushrooms, are gaining momentum owing to their unique physicochemical characteristics. Cucurbiturils, a class of synthetic macrocycles with intriguing and peculiar host–guest properties, have stimulated tremendous research interest in recent years. The marriage NMNPs cucurbiturils is expected integrate enhance the excellent characteristics both components, e.g., precisely controlled particle size, stability, assembly, surface...
Reactive metal–support interactions (RMSIs) induce the formation of bimetallic alloys and offer an effective way to tune electronic geometric properties metal sites for advanced catalysis. However, RMSIs often require high-temperature reductions (>500 °C), which significantly limits tuning compositional varieties. Here, we report that atomically thick Ga2O3 coating Pd nanoparticles enables initiation at a much lower temperature ∼250 °C. State-of-the-art microscopic in situ spectroscopic...
Core-shell bimetallic nanocatalysts have attracted long-standing attention in heterogeneous catalysis. Tailoring both the core size and shell thickness to dedicated geometrical electronic properties for high catalytic reactivity is important but challenging. Here, taking Au@Pd core-shell catalysts as an example, we disclose by theory that a large of Au with two monolayer Pd vital eliminate undesired lattice contractions ligand destabilizations optimum benzyl alcohol adsorption. A set...
Two-dimensional transition metal carbon/nitrides (MXenes) are promising candidates to revolutionize next-generation wearable sensors as high-performance surface-enhanced Raman scattering (SERS) substrates. However, low sensitivity of pure MXene nanosheets and weak binding force or uncontrolled in situ growth plasmonic nanoparticles on hybrid composites limit their progress toward universal reliable sensors. Herein, we designed manufactured a highly sensitive, structurally stable SERS sensor...
The detection of physiological phosphates (PPs) is great importance due to their essential roles in numerous biological processes, but the efficient different PPs simultaneously remains challenging. In this work, we propose a fluorescence sensor array for detecting based on metal-ion-regulated gold nanoclusters (AuNCs) via an indicator-displacement assay. Zn2+ and Eu3+ are selected assemble with two AuNCs, resulting quenching or enhancing fluorescence. Based competitive interaction metal...
Abstract The regeneration of hypoxia‐impaired chronic tissue defects has long been challenging, mainly due to the inefficiency oxygenation and limited biological activity existing oxygen delivery systems in regulating dynamic process. Herein, a novel polyphenol‐copper coordination strategy fabricate bioactive superoxide dismutase‐catalase self‐cascade nanozymes (SalB‐CuNCs) is reported, which can serve as an situ oxygenator induce angiogenesis simultaneously. copper‐phenolic hydroxyl...
We have demonstrated the design of a new type fluorescent assay based on inner filter effect (IFE) metal nanoparticles (NPs), which is conceptually different from previously reported NPs-based assays. With high extinction coefficient and tunable plasmon absorption feature, NPs are expected to be capable functioning as powerful absorber tune emission fluorophore in IFE-based In this work, we presented two proof-of-concept examples IFE Au by choosing MDMO-PPV model fluorophore, whose...
A lateral-flow (LF) device using the new reporter up-converting phosphor technology (UPT) was applied to DNA (hybridization) assays for detection of specific nucleic acid sequences, thereby aiming perform test outside well-equipped laboratories. The methodology reported here is sensitive and provides a rapid alternative more elaborate gel electrophoresis Southern blotting. In preliminary study, it screen presence human papillomavirus type 16 (HPV16) in defined series cervical carcinomas.A LF...
In this work, we report the first application of water-soluble fluorescent Ag nanoclusters in sensors. The fluorescence poly(methacrylic acid) (PMAA)-templated was found to be quenched effectively by Cu2+, but not when other common metal ions were present. By virtue specific response toward analyte, a new, simple, and sensitive method for detecting Cu2+ has been developed based on nanoclusters. present assay allows sensing range 1.0 × 10−8 M 6.0 10−6 with detection limit as low 8 nM at...