Noelia D. Machado

ORCID: 0000-0003-1578-9916
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About
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Research Areas
  • Advancements in Transdermal Drug Delivery
  • Polymer Foaming and Composites
  • biodegradable polymer synthesis and properties
  • Sirtuins and Resveratrol in Medicine
  • Phase Equilibria and Thermodynamics
  • Polymer crystallization and properties
  • Injection Molding Process and Properties
  • Advanced Drug Delivery Systems
  • Surfactants and Colloidal Systems
  • Fermentation and Sensory Analysis
  • Analytical Chemistry and Sensors
  • Nanocomposite Films for Food Packaging
  • Pharmacology and Obesity Treatment
  • Innovative Microfluidic and Catalytic Techniques Innovation
  • Microfluidic and Capillary Electrophoresis Applications
  • Chemical synthesis and alkaloids
  • Microplastics and Plastic Pollution
  • Sesquiterpenes and Asteraceae Studies
  • Aerogels and thermal insulation
  • Lignin and Wood Chemistry
  • Additive Manufacturing and 3D Printing Technologies
  • Photochemistry and Electron Transfer Studies
  • Bee Products Chemical Analysis
  • Pigment Synthesis and Properties
  • Consumer Packaging Perceptions and Trends

Universidad de Cádiz
2024-2025

Universidad Nacional de Córdoba
2018-2023

Consejo Nacional de Investigaciones Científicas y Técnicas
2018-2023

Centro Científico Tecnológico - Córdoba
2019-2020

Instituto de Investigaciones en Ciencias de la Salud
2018-2019

Resveratrol (RSV) is a natural polyphenol which produces several benefits to human health, being the trans-isomer most bioactive. However, its systemic absorption limited due low water solubility, that reduces oral bioavailability, and chemical instability (owing trans-cis RSV isomer conversion upon light irradiation). Thus, encapsulation of this bioactive compound required protect it from destructive environmental conditions. Here, trans-RSV was encapsulated in food grade nanovesicles...

10.3390/foods10050988 article EN cc-by Foods 2021-04-30

PETG (poly(ethylene glycol-co-cyclohexane-1,4-dimethanol terephthalate)) is an amorphous copolymer, biocompatible, recyclable, and versatile. Nowadays, it being actively researched for biomedical applications. However, proposals of as a platform the loading bioactive compounds from natural extract are scarce, well effect supercritical impregnation on this polymer. In work, filaments with Olea europaea leaf was investigated, evaluating pressure (100–400 bar), temperature (35–55 °C),...

10.3390/polym16111567 article EN Polymers 2024-06-01

Global fish consumption has steadily increased; however, fishery products are difficult to preserve. Active packaging emerged as an alternative improve its conservation. In this work, fresh hake fillets were packaged in commercial polylactic acid films impregnated with olive leaf extract using supercritical CO2. The impregnation was performed at 35 °C and 400 bar for 1 h. ABTS assay used determine the antioxidant activity, migration tests food simulants A D2 10 days 5 °C. control stored 12 4...

10.3390/app15020643 article EN cc-by Applied Sciences 2025-01-10

A series of biohydrogels based on mixtures kappa-carrageenan (κ-carrageenan, κ-C) and gelatin were evaluated as potential soft delivery vehicles for the encapsulation subsequent release non-ionic surfactant vesicles (niosomes) loaded with resveratrol (RSV). The niosomes prepared using a mixture amphiphilic lipids Tween 80 Span in water. results showed that RSV-niosomes did not significantly affect hydrogelation properties biopolymer mixture. Moreover, vitro drug experiments from containing...

10.1039/c8ra09655d article EN cc-by RSC Advances 2019-01-01

Pitaya is a fruit with high consumer acceptance and health benefits. peel waste product potential in the food industry, as an antioxidant enrichment natural colouring. Therefore, there interest recovering its constituents searching for pitaya species greater potential. This work aimed to obtain bioactive extracts from dried of fruits Selenicereus monacanthus (Lem.), S. costaricensis W. undatus H. using supercritical fluids at different pressures (100, 250 400 bar) ethanol-water 15% v/v or...

10.1002/jsfa.13383 article EN Journal of the Science of Food and Agriculture 2024-02-14

Niosomes were prepared from equimolar mixtures of two non-ionic surfactants, Span 80 and Tween 80. The capability the vesicular systems was studied through encapsulation azo dyes as molecular probes different hydrophobicity (methyl orange (MO) methyl yellow (MY)). To improve efficiency niosomes to encapsulate dyes, we employed an additional modification system, adding β-cyclodextrin (β-CD) or a modified amphiphilic β-CD (Mod-β-CD) niosomes. Neither inclusion nor incorporation produces...

10.1039/c8ra05021j article EN cc-by-nc RSC Advances 2018-01-01

The leaves of Olea europaea as agricultural waste represent a convenient source antioxidants. In combination with supercritical CO2 (scCO2), assisted impregnation is an interesting strategy for the preparation biomedical devices specific bioactivity. For this purpose, 3D-printable filaments thermoplastic polyurethane (TPU) and polylactic acid (PLA) were employed ethanolic olive extract (OLE) application. extraction OLE was performed using pressurized liquids. effect pressure (100-400 bar),...

10.3390/antiox11061170 article EN cc-by Antioxidants 2022-06-14

Cerebral ischemia represents the third cause of death and first disability in adults. This process results from decreasing cerebral blood flow levels as a result occlusion major artery. restriction supply generates low oxygen glucose, which leads to decrease energy metabolism cell, producing inflammation, finally, neurological deterioration. Currently, restoration is only effective approach therapy terms ischemic stroke. However, significant number patients still have poor prognosis,...

10.3390/neurosci2030022 article EN cc-by NeuroSci 2021-09-01

10.1016/j.saa.2020.118840 article EN Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy 2020-08-17
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