A5060959376- Biosensors and Analytical Detection
- Electrochemical sensors and biosensors
- Advanced biosensing and bioanalysis techniques
- Electrochemical Analysis and Applications
- Extracellular vesicles in disease
- Analytical chemistry methods development
- Analytical Chemistry and Sensors
- Advancements in Transdermal Drug Delivery
- Advanced Biosensing Techniques and Applications
- Microfluidic and Bio-sensing Technologies
- Analytical Chemistry and Chromatography
- Advanced Nanomaterials in Catalysis
- Gold and Silver Nanoparticles Synthesis and Applications
- Characterization and Applications of Magnetic Nanoparticles
- RNA Interference and Gene Delivery
- Surfactants and Colloidal Systems
- Advanced Drug Delivery Systems
- MicroRNA in disease regulation
- Lipid Membrane Structure and Behavior
- Nanoparticle-Based Drug Delivery
- Electrostatics and Colloid Interactions
- Microfluidic and Capillary Electrophoresis Applications
- Minerals Flotation and Separation Techniques
- Ferroelectric and Piezoelectric Materials
- Supercapacitor Materials and Fabrication
Universidad de Oviedo
2016-2025
Instituto de Biotecnología de León
2020
University of Gothenburg
2015
Universidad de Extremadura
2010
Instituto Nacional del Carbón
2000-2002
University of Leeds
1997-2000
Exosomes are cell‐secreted nanovesicles (40–200 nm) that represent a rich source of novel biomarkers in the diagnosis and prognosis certain diseases. Despite increasingly recognized relevance these vesicles as biomarkers, their detection has been limited due part to current technical challenges rapid isolation analysis exosomes. The complexity development analytical platforms relies on heterogeneous composition exosome membrane. One most attractive tests is inmunochromatographic strips,...
Extracellular vesicles (EV) are small membrane structures released by cells that act as potent mediators of intercellular communication. The study EV biology is important, not only to strengthen our knowledge their physiological roles, but also better understand involvement in several diseases. In the field biomedicine they have been studied a novel source biomarkers and drug delivery vehicles. most commonly used method for enrichment crude pellet involves serial centrifugation...
Establishing a definitive diagnosis of pneumonia using conventional tests is difficult and expensive. Lateral flow immunoassays (LFIAs) are an advantageous point care (POC) test option, but they have some limitations in terms detection quantification. In this work we developed lateral immunoassay for the ultrasensitive penumolysin employing plasmonic Surface-Enhanced Resonance Raman Scattering (SERRS) tag as labelled probe. The combination Au@Ag core–shell nanoparticles platform Rhodamine B...
Superparamagnetic nanoparticles have seen increased potential in medical and environmental applications. Their preparation is traditionally made by the coprecipitation method, with limited control over particle size distribution. Microemulsion methods could be advantageous due to efficient of size, shape, composition obtained. Water-in-oil (W/O) microemulsions consist aqueous microdomains dispersed a continuous oil phase, stabilized surfactant molecules. These work as nanoreactors where...
Tumour-derived exosomes can be released to serum and provide information on the features of malignancy, however, in order perform systematic studies biological samples, faster diagnostic techniques are needed, especially for detection low abundance proteins. Most human cancer cells positive at least one ligand activating immune receptor NKG2D presence plasma NKG2D-ligands associated with prognosis. Using MICA as example a tumour-derived antigen, endogenously expressed metastatic melanoma...
Abstract In this study, nanovesicles such as transfersomes, niosomes, and liposomes prepared by an ethanol injection method (EIM) formulated with soybean lecithin, Tween 80, Span 60, cholesterol, are used to improve the bioavailability of taxifolin, a natural antioxidant beneficial properties for health food preservation. Morphology, stability, in‐vitro release optimal formulations fully examined. The obtained results indicate that taxifolin‐loaded present sizes ranging between 98 215 nm...
In recent years, starch nanoparticles (SNPs) have attracted growing attention due to their unique properties as a sustainable alternative common nanomaterials since they are natural, renewable and biodegradable. SNPs can be obtained by the breakdown of granules through different techniques which include both physical chemical methods. The final strongly influenced synthesis method used well operational conditions, where controlled monodispersed size is crucial for certain bioapplications....
This paper describes the development of simple, sustainable, and low-cost strategies for signal enhancement on paper-based carbon platforms through gold nanoparticles electrogenerated from small volumes tetrachloroauric (III) acid solutions. Carbon ink is deposited a hydrophilic working area delimited with hydrophobic wax. maskless procedure fast cuts down waste. The connection this electrode to potentiostat ensured use screen-printed electrodes (SPEs). Close contact whole both improves...