Rehab A. Alshammari

ORCID: 0000-0003-1591-6540
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About
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Research Areas
  • Essential Oils and Antimicrobial Activity
  • Bee Products Chemical Analysis
  • Retinal Diseases and Treatments
  • Pharmaceutical Economics and Policy
  • Glaucoma and retinal disorders
  • Microbial Natural Products and Biosynthesis
  • Advancements in Transdermal Drug Delivery
  • Dendrimers and Hyperbranched Polymers
  • Biotechnology and Related Fields
  • Phytochemistry Medicinal Plant Applications
  • Antimicrobial Peptides and Activities
  • Pharmaceutical Quality and Counterfeiting
  • Drug-Induced Ocular Toxicity
  • RNA Interference and Gene Delivery

Almaarefa University
2022-2024

Alfaisal University
2022-2024

King Saud University
2022-2023

Presently, antimicrobial resistance is of great risk to remarkable improvements in health conditions and infection management. Resistance various antibiotics has been considered a obstacle their usage, necessitating alternative strategies for enhancing the antibacterial effect. Combination therapy recognized as considerable strategy that could improve therapeutic influence agents. Therefore, aim this study was combine action compounds natural origin like fusidic acid (FA) cinnamon essential...

10.3390/gels10040268 article EN cc-by Gels 2024-04-16

Ruboxistaurin (RBX) is an anti-vascular endothelial growth factor (anti-VEGF) agent that used in the treatment of diabetic retinopathy and mainly given intravitreally. To provide a safe effective method for RBX administration, this study was designed to develop nanoparticles using polyamidoamine (PAMAM) dendrimer generation 5 retinopathy. Drug loading efficiency, vitro release proposed complexes RBX: PAMAM dendrimers were determined complexation ratio showed highest possible efficiency...

10.3390/pharmaceutics14071444 article EN cc-by Pharmaceutics 2022-07-11

Skin infections considered as one of the predominant disorders that could greatly influence humans. Topical drug delivery is believed to be an effective substitute systemically delivered medication for skin management. Erythromycin has been proven retain anti-bacterial activity. Based on that, aim existent study develop a proper nanocarrier, namely; nanoemulsion using tea tree oil including Erythromycin. Applying quality by design approach, optimized was selected based number independent...

10.1016/j.jsps.2024.102152 article EN cc-by-nc-nd Saudi Pharmaceutical Journal 2024-07-28

This observational descriptive study that was carried out with the objective of exploring contribution local pharmaceutical industry to Saudi drug security. Using a formulary provided from Food and Drug Authority, containing all registered products available in Arabia, we extracted information about class, type, country place manufacturing, shelf-life price. Results showed majority drugs market are manufactured Europe (43.86%), followed by Arabia (22.55%), China India (20.47%), Americas...

10.1016/j.jsps.2023.03.001 article EN cc-by Saudi Pharmaceutical Journal 2023-03-08

Ruboxistaurin (RBX) used to treat retinopathy in diabetic patients which caused by microvascular damage and leakage contributes visual loss. There are no published studies on the use of liquid chromatography-tandem mass spectrometry for development validation a simple, sensitive, accurate method measuring RBX rat plasma.Chromatographic separation was achieved using ultra-performance chromatography. Multiple-reaction monitoring quantification [M + H] ion at m/z 469.18 daughter ions 84, 58.12,...

10.1016/j.jsps.2023.02.007 article EN cc-by-nc-nd Saudi Pharmaceutical Journal 2023-02-25
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