A5060979297- Cancer-related cognitive impairment studies
- Estrogen and related hormone effects
- Dementia and Cognitive Impairment Research
- Breast Cancer Treatment Studies
- Obsessive-Compulsive Spectrum Disorders
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Eating Disorders and Behaviors
- Glioma Diagnosis and Treatment
- Schizophrenia research and treatment
- Neural and Behavioral Psychology Studies
- Vestibular and auditory disorders
- Perfectionism, Procrastination, Anxiety Studies
- Sustainability, Governance, and Employment Studies
- Child Nutrition and Feeding Issues
- Privacy, Security, and Data Protection
- Crime, Deviance, and Social Control
- Cancer Treatment and Pharmacology
- Menopause: Health Impacts and Treatments
- Neurological Disease Mechanisms and Treatments
- Brain Metastases and Treatment
- Cancer survivorship and care
The Netherlands Cancer Institute
2007-2023
Altrecht GGZ
2016-2021
Utrecht University
2016
Medisch Centrum Haaglanden
2011-2014
Radboud University Nijmegen
2010
University of Amsterdam
2010
Radboud University Medical Center
2010
Oncode Institute
2007
To evaluate the influence of adjuvant tamoxifen and exemestane on cognitive functioning in postmenopausal patients with breast cancer (BC).Neuropsychological assessments were performed before start (T1) after 1 year endocrine treatment (T2) Dutch BC, who did not receive chemotherapy. Patients participated international Tamoxifen Exemestane Adjuvant Multinational trial, a prospective randomized study investigating versus as therapy for hormone-sensitive BC.Participants included 80 users (mean...
Background. Previous studies have indicated that a subset of cancer patients treated with chemotherapy show cognitive deficits and/or experience complaints, whereas literature about the influence hormonal therapies on cognition is sparse. Because accumulating knowledge importance estrogen for functioning, there growing concern adjuvant therapy breast (BC) affecting cognition. We examined functioning postmenopausal BC who were, following doxorubicin/cyclophosphamide (AC) chemotherapy,...
Endocrine therapy is widely used-often for many years-in women with breast cancer. Yet little known about cognitive functioning after long-term use of tamoxifen. We examine sequelae, approximately 3 years diagnosis, in postmenopausal cancer who were treated adjuvant tamoxifen.Data from participants underwent surgical operation or without radiotherapy, received tamoxifen, and healthy controls collected. Neuropsychological tests administered, completed questionnaires on health-related quality...
This study aimed to evaluate self-reported cognitive functioning of postmenopausal breast cancer patients before and during endocrine treatment compared with healthy female controls, investigate associations between functioning, test performance anxiety/depression, fatigue, menopausal complaints.Self-reported complaints, tests were assessed (T1) after 1 year (T2) adjuvant in chemotherapy-naïve patients. Self-reported was by the failures questionnaire interview questions concerning...
Abstract Objective : Several prospective studies into the effects of adjuvant systemic therapy on cognitive functioning suggest that a proportion breast cancer patients show deficits already before start therapy. Owing to, among others, methodological inconsistency, report different rates this pre‐treatment impairment. We examined impact four criteria impairment and two types reference groups (a study‐specific healthy group versus published normative data) prevalence Methods Two hundred five...
High performance at school is associated with the risk of eating disorders (EDs), and perfectionism proposed as an explanatory factor for this association. This study aims to evaluate (a) potential discrepancies between measured IQ adolescents EDs that expected given their educational track, (b) what extent was achievement independent from IQ.WISC-III Verbal IQ, Performance Full Scale 386 adolescent ED patients were compared population norms using one-sample t tests. The association...
Abstract Background Cognitive effects of tamoxifen have been described. We augment data from a previous short-term (ST) follow-up study with long-term (LT) to evaluate ST and LT cognitive followed by exemestane in breast cancer patients. Methods Patients the Tamoxifen Exemestane Adjuvant Multinational trial received 5 years (exemestane group, n = 114) or 2.5 (sequential 92). Neuropsychological performance was assessed pre-endocrine therapy, after 1 year (ST follow-up) at (LT follow-up). A...
ABSTRACT Objective Intelligence is a known vulnerability marker in various psychiatric disorders. In eating disorders (ED) intelligence has not been studied thoroughly. Small‐scale studies indicate that levels might be above general population norms, but larger scale are lacking. The aim of this study was to determine intellectual functioning ED patients and associations with severity the disorder. Methods: Wechsler's Full IQ (FSIQ), Verbal (VIQ) Performance (PIQ) 703 adolescent adult were...
We investigated whether forensic psychiatric inpatients can be distinguished from prisoners and healthy controls on the basis of their performance cognitive tasks measuring flexibility (with a reversal learning task) inhibition stop signal task). Forensic were expected to perform worse compared prisoners. This study was based pre-existing data N = 241 males (119 inpatients, 57 65 controls). fitted logistic generalized linear models group membership using outcome measures task examine...
566 Background: Cognitive deficits and cognitive complaints in daily life have been associated with adjuvant chemotherapy breast cancer survivors. The role of endocrine treatments respect to these problems is unclear. Because estrogen deficiency may adverse effects on certain functions, it plausible that affect functioning addition chemotherapy. current aim was investigate whether patients treated AC-chemotherapy therapy differs from healthy controls examine possible distinctive between...
Objective The main aim was to investigate whether forensic psychiatric inpatients can be distinguished from prisoners and non-offender healthy controls based on their performance neurocognitive tasks measuring behavioral inhibition activation. Method This study used preexisting data 120 male inpatients, 60 66 controls. A multinomial logistic regression analysis the links between our outcome measures group membership. To this end, we a Continuous Performance task, an emotional Stroop task...