A5039468626- Cancer survivorship and care
- Cancer-related cognitive impairment studies
- Childhood Cancer Survivors' Quality of Life
- Health Systems, Economic Evaluations, Quality of Life
- Dental Health and Care Utilization
- Ovarian cancer diagnosis and treatment
- Family Support in Illness
- Brain Metastases and Treatment
- Patient-Provider Communication in Healthcare
- Menopause: Health Impacts and Treatments
- Palliative Care and End-of-Life Issues
- Intraperitoneal and Appendiceal Malignancies
- Economic and Financial Impacts of Cancer
- Glioma Diagnosis and Treatment
- Global Cancer Incidence and Screening
- Cancer Treatment and Pharmacology
- Oral microbiology and periodontitis research
- BRCA gene mutations in cancer
- Patient Satisfaction in Healthcare
- Prostate Cancer Diagnosis and Treatment
- Reliability and Agreement in Measurement
- Prostate Cancer Treatment and Research
- Lymphoma Diagnosis and Treatment
- Dental Radiography and Imaging
- Sexual function and dysfunction studies
The Netherlands Cancer Institute
2016-2025
Oncode Institute
2014-2021
University of Groningen
2018-2019
Netherlands Comprehensive Cancer Organisation
2016-2019
Amsterdam UMC Location University of Amsterdam
2017-2018
Gynecologic Oncology Group
2018
St. Antonius Ziekenhuis
2018
University Medical Center
2018
University Medical Center Utrecht
2018
Catharina Ziekenhuis
2018
Treatment of newly diagnosed advanced-stage ovarian cancer typically involves cytoreductive surgery and systemic chemotherapy. We conducted a trial to investigate whether the addition hyperthermic intraperitoneal chemotherapy (HIPEC) interval would improve outcomes among patients who were receiving neoadjuvant for stage III epithelial cancer.In multicenter, open-label, phase 3 trial, we randomly assigned 245 had at least stable disease after three cycles carboplatin (area under curve 5 6 mg...
We evaluated the effectiveness of a low-intensity, home-based physical activity program (Onco-Move) and moderate- to high-intensity, combined supervised resistance aerobic exercise (OnTrack) versus usual care (UC) in maintaining or enhancing fitness, minimizing fatigue, health-related quality life, optimizing chemotherapy completion rates patients undergoing adjuvant for breast cancer.We randomly assigned who were scheduled undergo (N = 230) Onco-Move, OnTrack, UC. Performance-based...
The purpose of our study was to evaluate the effect cognitive behavioral therapy (CBT), physical exercise (PE), and these two interventions combined (CBT/PE) on menopausal symptoms (primary outcome), body image, sexual functioning, psychological well-being, health-related quality life (secondary outcomes) in patients with breast cancer experiencing treatment-induced menopause.Patients reporting (N=422) were randomly assigned CBT (n=109), PE (n=104), CBT/PE (n=106), or a waiting list control...
No AccessJournal of UrologyAdult Urology1 Oct 2014Quality Life for Patients Treated Penile Cancer Jacobien M. Kieffer, Rosa S. Djajadiningrat, Erik A.M. van Muilekom, Niels Graafland, Simon Horenblas, and Neil K. Aaronson KiefferJacobien Kieffer Division Psychosocial Research Epidemiology, Netherlands Institute, Amsterdam, the , DjajadiningratRosa Djajadiningrat Department Urology, MuilekomErik Muilekom GraaflandNiels Graafland HorenblasSimon Horenblas AaronsonNeil View All Author...
Purpose We evaluated the effect of Internet-based cognitive behavioral therapy (CBT) on sexual functioning and relationship intimacy (primary outcomes) body image, menopausal symptoms, marital functioning, psychological distress, health-related quality life (secondary in breast cancer survivors (BCSs) with a DSM-IV diagnosis dysfunction. Patients Methods randomly assigned 169 BCSs to either CBT or waiting-list control group. The consisted weekly therapist-guided sessions, maximum duration 24...
Health-Related Quality of Life (HRQoL) research has typically adopted either a formative approach, in which HRQoL is the common effect its observables, or reflective approach--defining as latent variable that determines observable characteristics HRQoL. Both approaches, however, do not take into account complex organization these characteristics. The objective this study was to introduce new approach for analyzing data, namely network model (NM). An NM, opposed traditional strategies,...
Background: Most cancer survivors are able to return work at some point after diagnosis. However, literature on sustained employability and health-related quality of life (HRQoL) is limited. Therefore, the aims this study were explore influence change in employment status HRQoL long term diagnosis, identify predictors continuation occupationally active survivors.Material methods: We used prospective data (T0 = two years T1 one-year follow-up, T2 two-year follow-up) from a cohort that had an...
We evaluated the effect of Internet-based cognitive behavioral therapy (iCBT), with or without therapist support, on perceived impact hot flushes and night sweats (HF/NS) overall levels menopausal symptoms (primary outcomes), sleep quality, HF/NS frequency, sexual functioning, psychological distress, health-related quality life in breast cancer survivors treatment-induced symptoms.We randomly assigned 254 to a therapist-guided self-managed iCBT group waiting list control group. The 6-week...
Introduction: To facilitate large-scale assessment of a variety cognitive abilities in clinical studies, we developed self-administered online neuropsychological test battery: the Amsterdam Cognition Scan (ACS). The current studies evaluate group adult cancer patients: test–retest reliability ACS and influence setting (home or hospital), relationship between our traditional battery (concurrent validity). Method: Test–retest was studied 96 patients (57 female; Mage = 51.8 years) who completed...
(Abstracted from N Engl J Med 2018;378:230–240) The majority of patients with ovarian cancer (OC) receive an initial diagnosis advanced disease that has spread the ovaries to peritoneal surface. most effective treatment for is cytoreductive surgery followed by systemic chemotherapy.
In the randomized open-label phase III OVHIPEC trial, addition of hyperthermic intraperitoneal chemotherapy (HIPEC) to interval cytoreductive surgery (CRS) improved recurrence-free and overall survival in patients with stage ovarian cancer. We studied cost effectiveness HIPEC CRS cancer.We constructed a Markov health-state transition model measure costs clinical outcomes. Transition probabilities were derived from trial by fitting distributions. Incremental cost-effectiveness ratio (ICER),...
The aim of this work was to assess the association among oral health, general and quality life (QoL). Oral Health Impact Profile (OHIP‐49) RAND‐36 were distributed amongst 118 psychology freshmen. Additionally, two single items self‐rated health (SRGH) (SROH) – administered. Kruskal–Wallis Mann–Whitney U ‐tests used evaluate differences between SRGH SROH categories, regarding OHIP subscale scores RAND scores. More than 75% subjects rated their as good. Mean indicated a relatively good oral‐...
When assessing the feasibility of surveillance for pancreatic cancer (PC), it is important to address its psychological burden. The aim this ongoing study evaluate burden annual individuals at high risk develop PC.This a multicenter prospective study. High-risk who undergo with magnetic resonance imaging (MRI) and endoscopic ultrasound (EUS) were invited complete questionnaires assess motivations participating in surveillance, experiences participation, perceived PC risk, topics concern,...