- Acute Ischemic Stroke Management
- Cerebrovascular and Carotid Artery Diseases
- Traumatic Brain Injury and Neurovascular Disturbances
- Cerebrovascular and genetic disorders
- Intracranial Aneurysms: Treatment and Complications
- Stroke Rehabilitation and Recovery
- Parathyroid Disorders and Treatments
- Pharmacological Effects and Toxicity Studies
- Magnesium in Health and Disease
- Peripheral Artery Disease Management
- Intracerebral and Subarachnoid Hemorrhage Research
- Alzheimer's disease research and treatments
Hospital Universitari de Girona Doctor Josep Trueta
2023-2025
Institut d'Investigació Biomèdica de Girona
2022-2024
<h3>Importance</h3> It is estimated that only 27% of patients with acute ischemic stroke and large vessel occlusion who undergo successful reperfusion after mechanical thrombectomy are disability free at 90 days. An incomplete microcirculatory might contribute to these suboptimal clinical benefits. <h3>Objective</h3> To investigate whether treatment adjunct intra-arterial alteplase improves outcomes following reperfusion. <h3>Design, Setting, Participants</h3> Phase 2b randomized,...
ABSTRACT Background and Purpose The superiority of achieving modified Treatment in Cerebral Ischemia (mTICI) from multiple passes versus mTICI 2b a single pass remains uncertain. We aimed to assess whether additional M1 occlusion patients with first‐pass score improved clinical functional outcomes. Methods analyzed Registry Combined vs. Single Thrombectomy Techniques registry data consecutive M1‐occlusion patients, comparing outcomes those 2b‐stopped after the first continued mechanical...
Background: A 61-year-old male patient presented with cerebellar syndrome, which had progressively worsened for 10 days, followed by a tonic-clonic seizure. Phenomenology Shown: Blood analysis showed severe hypomagnesemia and brain MRI T2 hyperintensity in the hemispheres (Figure 1). Therefore, final diagnosis was syndrome epileptic seizures secondary to hypomagnesemia. Educational Value: In cases of subacute onset ataxia, possibility ataxia should be considered, as it can diagnosed basic...
Introduction: In patients with acute ischemic stroke (AIS) secondary to intracranial large vessel occlusion, optimal blood pressure (BP) management following endovascular treatment (EVT) has not yet been established. The randomized trial on Hemodynamic Optimization of Cerebral Perfusion after Successful Endovascular Therapy in Patients Acute Ischemic Stroke (HOPE) (clinicaltrials.gov id: NCT04892511) aims demonstrate whether hemodynamic optimization using different systolic BP targets EVT...