To assess the efficacy of single-agent therapy relative to standard combination antibiotic for initial management fever and neutropenia in cancer patients, we conducted a randomized trial comparing ceftazidime alone with cephalothin, gentamicin, carbenicillin. Of 550 evaluable episodes neutropenia, 282 were treated 268 combination. All evaluated responses at 72 hours after start treatment resolution neutropenia. patients unexplained who given alone, 99 percent alive 98 when resolved, as...

Executive Summary This document serves as an update and companion piece to the 2005 Society for Healthcare Epidemiology of America (SHEA) Position Paper entitled “Influenza Vaccination Workers Vaccine Allocation During Shortages.” In large part, discussion about rationale influenza vaccination healthcare personnel (HCP), strategies designed improve rates in this population, recommendations made paper still stand. position notes new evidence released since publication strengthens SHEA's on...

No AccessJournal of Urology1 May 1987A Randomized Trial Comparing Ceftazidime Alone With Combination Antibiotic Therapy in Cancer Patients Fever and Neutropenia P.A. Pizzo, J.W. Hathorn, J. Hiemenz, M. Browne, Commers, D. Cotton, Gress, Longo, Marshall, McKnight, Rubin, Skelton, Thaler, R. Wesley PizzoP.A. Pizzo More articles by this author , HathornJ.W. Hathorn HiemenzJ. Hiemenz BrowneM. Browne CommersJ. Commers CottonD. Cotton GressJ. Gress LongoD. Longo MarshallD. Marshall McKnightJ....

OBJECTIVES: Noninvasive markers of liver fibrosis correlate with the stage fibrosis, but have not been widely applied to predict liver-related mortality. METHODS: We assessed ability two indices aspartate aminotransferase (AST)-to-platelet ratio index (APRI) and Fib-4, extracellular matrix metabolism, hyaluronic acid (HA) YKL40, mortality in a prospective cohort hepatitis C virus (HCV)-infected individuals without HIV coinfection. These were compared established prognostic scores,...

Zidovudine therapy is recommended for asymptomatic patients infected with the human immunodeficiency virus (HIV) who have fewer than 500 CD4+ cells per cubic millimeter. An analysis of quality life associated that integrated both effects adverse events and benefits delayed disease progression might influence this recommendation.

Although human immunodeficiency virus (HIV) disease is increasing rapidly among women, no prior studies have investigated gender-based therapeutic strategies for the treatment of acquired syndrome (AIDS) and its complications in this population. Markedly decreased serum androgen levels been demonstrated women with AIDS may be a contributing factor to wasting To assess effects replacement therapy wasting, we conducted randomized, placebo-controlled, pilot study transdermal testosterone...

Special Articles21 December 2020COVID-19 Vaccine: Promoting Vaccine AcceptanceFREEChristine Laine, MD, MPH, Deborah Cotton, and Darilyn V. Moyer, MDChristine MPHEditor in Chief Annals of Internal Medicine Search for more papers by this author, MPHDeputy Editor MDExecutive Vice President Executive OfficerAmerican College PhysiciansSearch authorAuthor, Article, Disclosure Informationhttps://doi.org/10.7326/M20-8008 SectionsAboutVisual AbstractPDF ToolsAdd to favoritesDownload CitationsTrack...

Objective: To evaluate the effects of zidovudine therapy in patients with mildly symptomatic HIV infection using Q-TWiST (quality-adjusted: Time Without Symptoms and Toxicity). Design: Analysis a previously reported multicenter, randomized, placebo-controlled clinical trial. Setting: Thirty-two AIDS Clinical Trial units. Patients: A total 351 were assigned to placebo, 360 zidovudine, 1200 mg/d. Measurements: modified method for comparing treatments based on time spent without severe adverse...

Objective: To prospectively examine differences in baseline characteristics and study outcomes between HIV-infected women men during a clinical trial of nucleoside analogue therapy. Methods: ACTG 175 randomized patients with CD4+ counts 200 500 cells/mm3 to one four regimens: zidovudine (ZDV), didanosine (ddl), ZDV + ddI, or zalcitabine (ddC). Differences time first dose modification, voluntary withdrawal, development toxicity symptomatology, AIDS progression were compared by gender....

ABSTRACT This paper draws on a survey and interview data, collected from group of 180 donors who made monetary gifts to an Australian higher education institution, better understand what drives individuals organisations donate Indigenous initiatives. The analysis helped identify five types donors: the Advocate Prescriptive donors, supporter initiatives Constrained, Reserved Opposing non‐supporter withhold donating such results show wide range motivations, varied attitudes multiple perceived...

Objective: To prospectively examine differences in baseline characteristics and study outcomes between HIV-infected women men during a clinical trial of nucleoside analogue therapy. Methods: ACTG 175 randomized patients with CD4+ counts 200 500 cells/mm3 to one four regimens: zidovudine (ZDV), didanosine (ddl), ZDV + ddI, or zalcitabine (ddC). Differences time first dose modification, voluntary withdrawal, development toxicity symptomatology, AIDS progression were compared by gender....

Sustainability learning is holistic and complex as it draws on diverse disciplines can be interpreted differently within individual pedagogies. Embedding sustainability across business schools relies developing suitable boundary objects. These may include representations such models, frameworks or classificatory schemes that are malleable enough to adapted for use the disparate pedagogies, yet durable recognisable maintain consistency them. Boundary objects thus allow sharing of ways knowing...

IN THIS eighth year of the war against acquired immunodeficiency syndrome (AIDS), front lines in United States are surely hospitals our major cities. It is to these institutions that afflicted come, whatever their risk group, and increasing numbers. Gay bisexual men bring with them a history discrimination fear. Drug users reveal an entire family at risk. The worried well crowd clinics be tested for infection second, third, or fourth time. People come hope being given latest experimental...

Summary: The pattern of the development opportunistic infections (OIs) in HIV-infected patients was evaluated, based on a cohort 1,530 enrolled two AIDS Clinical Trials Group anti-retroviral studies. We quantified increase risk OIs associated with occurrence previous OI. This assessment observed event rates more common AIDS-defining OIs: Pneumocystis carinii pneumonia (PCP), Mycobacterium avium complex (MAC), cytomegalovirus (CMV), and systemic mycosis. Additionally, for each OI, we assessed...

Surveys have shown that dentists are reluctant to treat persons infected with the human immunodeficiency virus (HIV). However, much more willing patients infectious hepatitis B (HBV). This study shows annual cumulative risk of infection from routine treatment whose seropositivity is undisclosed 57 times greater HBV than HIV, and dying 1.7 HIV infection, for which mortality almost certain.

Cervical cancer is a leading cause of death for women in Latin America, and vaccinating against human papillomavirus (HPV) has the potential to limit this disease. We sought determine Honduran women's awareness HPV vaccination interest their daughters HPV.We interviewed mothers aged ≥17 at primary care clinics Honduras. First, we collected demographic information assessed knowledge related cervical prevention vaccination. Because most participants were not familiar with HPV, education about...

Coinfection with hepatitis C (HCV) significantly increases the risk of acute and chronic renal disease in HIV-infected individuals. However, burden kidney injury (AKI) directly attributable to HIV among HCV-infected individuals associated factors are not well understood. Within a prospective cohort, AKI episodes were identified by rise creatinine 0.5 mg/dL. Incidence first events was calculated for HIV/HCV coinfected versus HCV monoinfected subjects, multivariable analyses using Cox...