A5024223058- Insect and Pesticide Research
- Plant and animal studies
- Insect and Arachnid Ecology and Behavior
- Parasitic Infections and Diagnostics
- Plant and Fungal Interactions Research
- Winter Sports Injuries and Performance
- Insect symbiosis and bacterial influences
- Botulinum Toxin and Related Neurological Disorders
- Facial Nerve Paralysis Treatment and Research
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Marine Biology and Environmental Chemistry
- Plant Virus Research Studies
- Stroke Rehabilitation and Recovery
- Reproductive biology and impacts on aquatic species
- Environmental Toxicology and Ecotoxicology
- Plant Disease Management Techniques
- Invertebrate Immune Response Mechanisms
- Selenium in Biological Systems
- Sperm and Testicular Function
- Technology and Security Systems
- Maternal and Perinatal Health Interventions
- Facial Rejuvenation and Surgery Techniques
- Balance, Gait, and Falls Prevention
- Educational Technology and Pedagogy
- Heart Rate Variability and Autonomic Control
Bengbu Medical College
2023-2025
Dalian Medical University
2024
First Affiliated Hospital of Dalian Medical University
2024
Chongqing Normal University
2005-2024
Institute of Automation
2024
University of Chinese Academy of Sciences
2021-2024
Ministry of Agriculture and Rural Affairs
2023-2024
Yangtze Normal University
2023
State Key Laboratory of Freshwater Ecology and Biotechnology
2023
Institute of Hydrobiology
2021-2023
Microsporidian Nosema bombycis has received much attention because the pébrine disease of domesticated silkworms results in great economic losses silkworm industry. So far, no effective treatment could be found for pébrine. Compared to other known parasites, N. can unusually parasitize a broad range hosts. To gain some insights into underlying genetic mechanism pathological ability and host expansion this parasite, comparative genomic approach is conducted. The genome two antheraeae (an...
Imidacloprid is a global health threat that severely poisons the economically and ecologically important honeybee pollinator, Apis mellifera . However, its effects on developing bee larvae remain largely unexplored. Our pilot study showed imidacloprid causes developmental delay in larvae, but underlying toxicological mechanisms incompletely understood. In this study, we exposed to at environmentally relevant concentrations of 0.7, 1.2, 3.1, 377 ppb. There was marked dose-dependent larval...
Microsporidia are a group of eukaryotic intracellular parasites that infect almost all vertebrates and invertebrates. The microsporidian invasion process involves the extrusion unique polar tube into host cells. Both spore wall play an important role in pathogenesis. So far, five proteins (SWP1, SWP2, Enp1, Enp2, EcCDA) from Encephalitozoon intestinalis cuniculi (SWP32, SWP30, SWP26, SWP25, NbSWP5) silkworm pathogen Nosema bombycis have been identified. Here we report identification...
Imidacloprid severely poisons the nontarget insect honey bee Apis mellifera. Few treatments are available to mitigate adverse effects of imidacloprid. The primary concern is that molecular understanding imidacloprid toxicity not comprehensive enough. Oxidative stress pathophysiological mechanism by which pesticides cause high mortality. Our pilot study found for first time stimulates brains secrete melatonin, a free radical scavenger. However, basis and role melatonin in coping with have...
ABSTRACT Microsporidia are obligate intracellular parasites with rigid spore walls that protect against various environmental pressures. Despite an extensive description of the wall, little is known regarding mechanism by which it deposited or role plays in cell adhesion and infection. In this study, we report identification characterization two novel wall proteins, SWP7 SWP9, microsporidian species Nosema bombycis . SWP9 mainly localized to exospore endospore mature spores cytoplasm...
SUMMARY The spore wall of Nosema bombycis plays an important role in microsporidian pathogenesis. Protein fractions from germinated coats were analysed by two-dimensional polyacrylamide gel electrophoresis and MALDI-TOF/TOF mass spectrometry. Three protein spots identified as the hypothetical NbHSWP12. A BAR-2 domain (e-value: 1.35e-03) was protein, N-terminal protein-heparin interaction motif, a potential N-glycosylation site, 16 phosphorylation sites primarily activated kinase C also...
Imidacloprid, a neonicotinoid pesticide widely used for insect pest control, has become potential pollutant to pollinators. Previous reports have demonstrated the toxicity of this drug in activating oxidative stress resulting high mortality honey bee Apis mellifera. However, mechanisms underlying imidacloprid not been fully elucidated. In study, sublethal (36 ng/bee) and median lethal (132 doses were administered bees. The results showed dose-dependent increases reactive oxygen species...
Microsporidia have attracted considerable attention because they infect a wide range of hosts, from invertebrates to vertebrates, and cause serious human diseases major economic losses in the livestock industry. There are no prospective drugs counteract this pathogen. Eukaryotic protein kinases (ePKs) play central role regulating many essential cellular processes therefore potential drug targets. In study, comprehensive summary comparative analysis four microsporidia–Enterocytozoon bieneusi,...
Ascosphaera apis is an intestinally infective, spore-forming, filamentous fungus that infects honeybees and causes deadly chalkbrood disease. Although A. has been known for 60 y, little about the ultrastructure of spores. In this study, fine morphology isolate, CQ1 from southwest China, was comprehensively identified by transmission electron microscopy, confocal laser scanning optical microscopy. The high sequence similarity phylogenetic data based on nuc rDNA ITS1-5.8S-ITS2 (ITS) supported...
SUMMARY Parasite–host interactions mediated by cell surface proteins have been implicated as a critical step in infections caused the microsporidian Nosema bombycis . Such are considered promising diagnostic markers and targets for drug development. However, little research has specifically addressed proteome identification microsporidia due to technical barriers. Here, combined strategy was developed separate identify of N. Briefly, following (1) biotinylation spore surface, (2) extraction...
Chinese sacbrood disease (CSD), which is caused by virus (CSBV), a major viral in Apis cerana larvae. Analysis of lipid composition critical to the study CSBV replication. The host lipidome profiling during infection has not been conducted. This paper identified CSBV–larvae interaction through high-resolution mass spectrometry. A total 2164 lipids were detected and divided into 20 categories. Comparison between healthy infected-larvae showed that 266 species altered infection. Furthermore,...
Imidacloprid is a global health threat that severely poisons the economically and ecologically important honeybee pollinator, Apis mellifera. However, its effects on developing bee larvae remain largely unexplored. Our pilot study showed imidacloprid causes developmental delay in larvae, but underlying toxicological mechanisms incompletely understood. In this study, we exposed to at environmentally relevant concentrations of 0.7, 1.2, 3.1, 377 ppb. There was marked dose-dependent larval...
Imidacloprid is a global health threat that severely poisons the economically and ecologically important honeybee pollinator, Apis mellifera . However, its effects on developing bee larvae remain largely unexplored. Our pilot study showed imidacloprid causes developmental delay in larvae, but underlying toxicological mechanisms incompletely understood. In this study, we exposed to at environmentally relevant concentrations of 0.7, 1.2, 3.1, 377 ppb. There was marked dose-dependent larval...