A5019574948- Electrospun Nanofibers in Biomedical Applications
- Cardiac and Coronary Surgery Techniques
- Tissue Engineering and Regenerative Medicine
- RNA Interference and Gene Delivery
- Natural Products and Biological Research
- Oil Palm Production and Sustainability
- Trypanosoma species research and implications
- Agricultural and Food Production Studies
- Bacteriophages and microbial interactions
- Marine Ecology and Invasive Species
- Antimicrobial Peptides and Activities
- Subterranean biodiversity and taxonomy
- biodegradable polymer synthesis and properties
- Bone Tissue Engineering Materials
- Graphene and Nanomaterials Applications
- Additive Manufacturing and 3D Printing Technologies
- Sugarcane Cultivation and Processing
- Aquatic Invertebrate Ecology and Behavior
- Chromatography in Natural Products
- Insect symbiosis and bacterial influences
- Nanoparticle-Based Drug Delivery
Universidad del Valle de México
2022
Universidad de Los Andes
2018-2021
Introduction: Controlled delivery of therapeutic molecules in a localized manner has become an area interest due to its potential reduce drug exposure healthy tissues and consequently minimize undesirable side effects. We have recently introduced novel cell-penetrating vehicles by immobilizing the antimicrobial peptide Buforin II (BUF-II) on magnetite nanoparticles (MPNPs). Despite potent translocating abilities such nanobioconjugates, they failed preserve activity native BUF-II. In this...
One of the major challenges modern pharmacology is development systems for delivery therapeutic molecules in a controlled and localized manner. strategy to use nanostructured supports, which are well suited carry large number on per mass basis. A challenge these supports is, however, their limited ability bypass cell membrane. Recent studies propose that overcome this issue, potent translocating cell-penetrating peptides (CPPs) can be conjugated surfaces.Here, we antimicrobial CPP buforin II...
Non-centrifugal cane sugar (NCS) is a traditional sweetener in most sugarcane regions of the world. In Colombia, this product has socio-economic importance due to extensive cultivation area and high consumption rate per capita. NCS processing involves consecutive stages thermal that begin with juice extraction, clarification, evaporation, finish syrup crystallization into solid commercial product, identified as NCS. Sugarcane known have natural content polyphenols, amino acids, vitamins,...
Oil palm plantation establishment in Colombia has the potential to impact Chagas disease transmission by increasing distribution range of Rhodnius prolixus. In fact, previous studies have reported Trypanosoma cruzi natural infection R. prolixus captured oil palms (Elaeis guineensis) Orinoco region, Colombia. The aim this study is understand T. vectors plantations relative community composition and host dietary specialization analyzing vector blood meals comparing these results a native tree...
Currently available small diameter vascular conduits present several long-term limitations, which has prevented their full clinical implementation. Commercially grafts show no regenerative capabilities and eventually require surgical replacement; therefore, it is of great interest to develop alternative (RVG). Decellularized Small Intestinal Submucosa (SIS) an attractive material for RVG, however, the evaluation performance these challenging due absence devices that mimic conditions found in...
The lack of success small diameter vascular grafts (<;6 mm) has driven biomedical engineers to develop multiple strategies for their improvement. One the most promising proposals involves formation a healthy and uniform endothelial layer. early this tissue on lumen graft prevents thrombosis excessive proliferation smooth muscle cells, which can lead intimal hyperplasia. Based theory, Biomedical Engineering Group at Universidad de los Andes (GIB) is currently working smalldiameter made...