- Plasma Applications and Diagnostics
- Semiconductor materials and devices
- Plasma Diagnostics and Applications
- Semiconductor materials and interfaces
- Electrohydrodynamics and Fluid Dynamics
- Radiation Therapy and Dosimetry
- Advanced Radiotherapy Techniques
- Catalytic Processes in Materials Science
- Radiopharmaceutical Chemistry and Applications
- Silicon and Solar Cell Technologies
- Electron and X-Ray Spectroscopy Techniques
- Semiconductor Quantum Structures and Devices
- Integrated Circuits and Semiconductor Failure Analysis
- Cancer Immunotherapy and Biomarkers
- Electronic and Structural Properties of Oxides
- Copper Interconnects and Reliability
- CO2 Sequestration and Geologic Interactions
- Thin-Film Transistor Technologies
- Service-Oriented Architecture and Web Services
- Advanced Breast Cancer Therapies
- Nanoplatforms for cancer theranostics
- Silicon Nanostructures and Photoluminescence
- Cancer Treatment and Pharmacology
- Metal and Thin Film Mechanics
- Cancer, Stress, Anesthesia, and Immune Response
Leibniz Institute for Plasma Science and Technology
2013-2024
Johannes Gutenberg University Mainz
2023
Georg Simon Ohm University of Applied Sciences Nuremberg
2023
Fraunhofer Institute for Material Flow and Logistics
2014-2022
Universitätsmedizin Greifswald
2021
Tel Aviv University
2009-2020
University College Cork
2013-2018
University of Wuppertal
2005-2017
Tyndall National Institute
2017
Cedars-Sinai Medical Center
2010-2015
This paper reviews the most commonly used methods for generation of plasmas with special emphasis on non-thermal, low-temperature technological applications. We also discuss various technical realizations plasma sources selected is further limited to discussion that employ electric fields. The described include dc glow discharges, either operated continuously (CW) or pulsed, capacitively and inductively coupled rf helicon microwave discharges. Various examples in closed structures...
Web services based on the service-oriented architecture framework provide a suitable technical foundation for making business processes accessible within enterprises and across enterprises. But to appropriately support dynamic their management, more is needed, namely, ability prescribe how are used implement activities process, represented as services, also which partners perform what parts of actual process. In this paper, relationship between management worked out presented in tutorial-like manner.
The Enterprise Service Bus (ESB) is the infrastructure which underpins a fully integrated and flexible end-to-end service-oriented architecture (SOA). This paper details essential meta-data capabilities of ESB. It presents summary key concepts ESB defines integration model for it, including user roles. These roles are fulfilled using that describes service endpoints, such as interface policy requirements capabilities. manages this through registry, supports configuration, connection,...
Pulmonary fibrosis is a chronic progressive disease with no effective therapy. Transforming growth factor β (TGF- ) thought to be key profibrotic mediator and blocking its activity therefore one of the targets new treatment strategies for fibrosis. Decorin an endogenous proteoglycan known inhibitors TGF- . The short half-life peptide-based therapeutics makes gene transfer promising approach achieve prolonged protein levels in lung. Replication-deficient adenovirus was used deliver decorin...
The objective of this study was to compare the accuracy in staging various malignant tumors with whole-body magnetic resonance imaging (WB-MRI) using parallel (PAT) and positron emission tomography-computed tomography (PET-CT).In a prospective study, 41 patients withoncologic diseases underwent [F]-fluoro-2-deoxy-D-glucose PET-CT for tumor WB-MRI on 32-channel-scanner use PAT. Coronal T1w STIR sequences at 5 body levels, axial HASTE lung, contrast-enhanced liver, brain, abdomen were...
The viscosity of the Gangotri Himalayan leucogranite has been experimentally determined between 800° and 1100°C, 300 800 MPa, for meltwater contents 3.98 6.66 wt %. melt is independent pressure shows an Arrhenian behavior relative to temperature within range conditions investigated. We present empirical relation that can be used determine magma viscosities knowing their content temperature. This together with phase equilibria experiments constrain leucogranites around 10 4.5 Pa s during...
Ultrafast electromagnetic radiation induced by a femtosecond laser beam from semiconductor provides determination of the impurity doping concentration, carrier mobility, sign, and strength depletion field near surface.
A new method utilizing alpha particles to treat solid tumors is presented. Tumors are treated with interstitial radioactive sources which continually release short-lived emitting atoms from their surface. The disperse inside the tumor, delivering a high dose through decays. We implement this scheme using thin wire impregnated (224)Ra, by recoil (220)Rn, (216)Po and (212)Pb atoms. This work aims demonstrate feasibility of our measuring activity patterns released radionuclides in experimental...
A new configuration of a discharge chamber and power source for the treatment up to 1 L liquid is presented. leakage transformer, energizing two metal electrodes positioned above liquid, limits current inductively by utilizing weak magnetic coupling between primary secondary coils. No additional means avoid arcing (electric short-circuiting), e.g., dielectric barriers or resistors, are needed. By using this technique, exceeding breakdown voltage leads formation transient spark discharges,...
Abstract Diffusing alpha-emitters radiation therapy (DaRT) is the only known method for treating solid tumors with highly destructive alpha radiation. More importantly, as a monotherapy, DaRT has been shown to induce systemic antitumor immune response following tumor ablation. Here, immunomodulatory strategies boost induced by DaRT, and specificity, were investigated in colon cancer CT26 mouse model. Local treatment prior TLR3 agonist poly I:C, was sufficient inhibit growth relative I:C or...
Diffusing alpha-emitting radiation therapy (DaRT) employs intratumoral Ra-224-coated seeds that efficiently destroy solid tumors by slowly releasing atoms inside the tumor. In immunogenic tumor models, DaRT was shown to activate systemic antitumor immunity. Agonists of membrane-bound toll-like receptors (TLRs) enhanced these effects and led rejection. Here, we examined combination with agents a different type pattern recognition receptors, cytoplasmatic RIG1-like (RLRs). response viral...
A planar volume dielectric barrier discharge (DBD) in pure carbon dioxide (CO2) for the formation of monoxide (CO) is examined by combined electrical and CO density measurements. The influence type electrode, material, thickness, gap on plasma power analyzed systematically. characterization means charge-voltage plots based simplest equivalent circuit model DBDs, extended so-called partial surface effect presence parallel parasitic capacitances. stackable arrangement this study enables one to...
The surface chemistry of GaAs-oxide removal with an electron cyclotron resonance (ECR) hydrogen plasma has been investigated x-ray photoelectron spectroscopy. It is found that As oxide efficiently removed at room temperature, and heating expedites the Ga oxide. Band bending changes during ECR hydrogen-plasma reduction are also discussed.
Treating cancer is one of the major challenges modern medicine. Since mice models are an important tool in treatment research, it required to assess murine tumor development. Existing methods for investigating development either high cost and limited by their availability or suffer from low accuracy reproducibility. In order overcome these drawbacks, thermography may be used. DA3 breast carcinoma tumors 12 Balb/c were thermally imaged monitored a period several weeks. Eight treated with...
PURPOSE Although most patients with primary gastric low-grade mucosa-associated lymphoid tissue (MALT) B-cell lymphoma experience complete endoscopic and histologic remission after the cure of Helicobacter pylori infection, in many patients, polymerase chain reaction (PCR) still detects monoclonal B cells mucosa. The present study asked whether immunoglobulin VH (IgVH) sequences remained stable MALT H eradication. PATIENTS AND METHODS Eight stage EI disease treated eradication were analyzed...
In the present study, we examined antitumoral effects caused by release of alpha emitting radioisotopes into solid squamous cell carcinoma (SCC) tumors. Using a novel method termed DART (Diffusing Alpha-emitters Radiation Therapy), assessed efficacy short-lived daughters (224)Ra releasing particles, dispersing in malignant tissue, to cause tumor growth retardation and destruction. It was carried out using specially designed wires loaded with activities range 7-42 kBq set experiments...