A5039438928- RNA modifications and cancer
- Cancer-related molecular mechanisms research
- MicroRNA in disease regulation
- Circular RNAs in diseases
- Ferroptosis and cancer prognosis
- Aquatic Ecosystems and Phytoplankton Dynamics
- Eosinophilic Disorders and Syndromes
- Time Series Analysis and Forecasting
- Liver Disease Diagnosis and Treatment
- Fungal Infections and Studies
- Cytokine Signaling Pathways and Interactions
- Electrospun Nanofibers in Biomedical Applications
- Infectious Diseases and Mycology
- Geochemistry and Elemental Analysis
- Spondyloarthritis Studies and Treatments
- Heavy metals in environment
- Rheumatoid Arthritis Research and Therapies
- Forecasting Techniques and Applications
- 3D Printing in Biomedical Research
- Inflammatory Myopathies and Dermatomyositis
- Liver Disease and Transplantation
- Autoimmune and Inflammatory Disorders Research
- Ideological and Political Education
- Stock Market Forecasting Methods
- Immunodeficiency and Autoimmune Disorders
Affiliated Hospital of Youjiang Medical University for Nationalities
2021-2024
Daqing Oilfield General Hospital
2019-2024
Tianjin University of Technology
2023
Nantong University
2023
Shanghai University of Sport
2023
Tianjin University
2021
Zhengzhou University of Science and Technology
2018
Abstract Hepatocellular carcinoma (HCC) is the fifth most frequently diagnosed cancer and ranks third in cancer‐related fatalities. The recognized involvement of long noncoding RNAs (lncRNAs) several types, including HCC, inspired this study to explore a novel lncRNA's functional importance progression HCC. To achieve this, lncRNA microarray analysis was conducted on three distinct sets HCC tissues, revealing LINC00707 as significantly upregulated lncRNA. Further research into its biological...
Abstract Objectives Cuproptosis represents an innovative type of cell death, distinct from apoptosis, driven by copper dependency, yet the involvement apoptosis-associated long non-coding RNAs (CRLncRNAs) in hepatocellular carcinoma (HCC) remains unclear. This study is dedicated to unveiling role and significance these apoptosis-related lncRNAs within context HCC, focusing on their impact both development disease its prognosis. Methods We conducted analysis gene transcriptomic clinical data...
Abstract Hydrogels with injectability and robustness have great promise in clinical practice. However, current injectable hydrogels are usually mechanically weak. Here, an idea, “preformed hydrogel reversion”, is proposed to develop robust through intermediate unit‐mediated, continuous structural inheritance strategy. In this strategy, preformed physically disassembled into structure‐inherited microgels (SIMs), upon encountering water physiological environment, the SIMs can construct a...
Hepatocellular carcinoma (HCC) is a common malignant liver tumor worldwide. Tumor recurrence and metastasis contribute to the bad clinical outcome of HCC patients. Substantial studies have displayed lncRNAs modulate various tumorigenic processes many cancers. Our current work was aimed investigate function LINC00675 in recognize potential interactions between microRNAs. GFI1 can exhibit significant role progression human tumors. Firstly, identified using real-time PCR tissues cells. In this...
Ankylosing spondylitis (AS) is a chronic inflammatory rheumatic disease. MicroRNAs (miRNAs) are group of endogenous small non‑coding RNAs that regulate target genes, and play critical role in many biological processes. However, the underlying mechanism specific miRNA, miR‑130a‑3p, AS remains largely unknown. Therefore, present study aimed to explore miR‑130a‑3p development AS. In study, it was revealed downregulated T cells from HLA‑B27‑positive patients compared with HLA‑B27‑negative...
Accumulating evidence indicates that circular RNAs (circRNAs) can interact with microRNAs to modulate gene expression in various cancers, including hepatocellular carcinoma (HCC). Although the significant role of circRNAs has been well documented HCC, complex mechanisms still need be elucidated. Our current study is aimed at investigating function circ_0001588 which was observed significantly increase HCC tissues and cells. We demonstrated knockdown resulted repressed cell proliferation,...
Abstract Objective To explore the efficacy and safety of combination therapy with methotrexate (MTX) plus hydroxychloroquine (HCQ) vs. MTX monotherapy in patients rheumatoid arthritis (RA). Methods Sixty without prior RA treatments were randomly allocated a 1:1 ratio to two groups: one receiving HCQ, other monotherapy. We conducted comparative analysis before after 12‐week trial, evaluating visual analogue scale (VAS), disease activity score 28 joints (DAS), serum inflammatory factor...
We present the clinical data of a child with systemic lupus erythematosus (SLE) complicated by juvenile dermatomyositis (JDM, positive for anti-melanoma differentiation-associated protein 5 [MDA5] antibodies). The patient was 10-year-old girl chronic course disease, which mainly presented as red rashes on face and trunk, accompanied fever, multiple joint pain, alopecia, oral ulcers. She treated in several hospitals successively, antinuclear antibodies fluctuated between 1:320 1:640 positive,...
Metabolic flexibility (MetF) is the capacity of an organism to oxidate substrate according availability or demand. The mismatch and oxidation may cause ectopic fat accumulation in muscle liver. objectives study are examine effect 12 weeks combined exercise on hepatic reduction investigate metabolites related MetF before after high-fat diet between individuals with NAFLD healthy control active lifestyle. This open-label, single-center trial randomized controlled clinical plus a...
<title>Abstract</title> Objectives Cuproptosis is a novel form of copper-dependent non-apoptotic cell death, and the role copper apoptosis-associated long non-coding RNAs (CRLncRNAs) in hepatocellular carcinoma (HCC) has not been elucidated. In this study, we aimed to investigate significance apoptosis-related lncRNAs HCC tumorigenesis prognosis. Methods We analyzed gene transcriptomic data clinical cases by obtaining them from The Cancer Genome Atlas (TCGA). combined Cuproptosis-related...