A5082351232- Head and Neck Cancer Studies
- Ear and Head Tumors
- Salivary Gland Tumors Diagnosis and Treatment
- Tracheal and airway disorders
- Head and Neck Surgical Oncology
- Thyroid and Parathyroid Surgery
- Airway Management and Intubation Techniques
- Voice and Speech Disorders
- COVID-19 and healthcare impacts
- Thyroid Cancer Diagnosis and Treatment
- Data Quality and Management
- Facial Nerve Paralysis Treatment and Research
- Electronic Health Records Systems
- Cancer and Skin Lesions
- Soft tissue tumor case studies
- Sarcoma Diagnosis and Treatment
- Meningioma and schwannoma management
- Data-Driven Disease Surveillance
- Hearing Loss and Rehabilitation
- Cleft Lip and Palate Research
- Patient Safety and Medication Errors
- BRCA gene mutations in cancer
- Venous Thromboembolism Diagnosis and Management
- Healthcare Systems and Technology
- Cancer survivorship and care
University of North Carolina at Chapel Hill
2023-2025
Cleveland Clinic
2021-2022
University of Iowa Hospitals and Clinics
2017-2021
University of Iowa
2018-2019
To evaluate the long-term audiometric outcomes, sound localization abilities, binaural benefits, and tinnitus assessment of subjects with cochlear implant (CI) after a diagnosis unilateral severe-to-profound hearing loss.The study group consisted 60 (mean age 52 years, range 19-84) profound loss in one ear normal to near-normal other who underwent CI. Data analysis included pre- postoperative Consonant-Nucleus-Consonant (CNC) Word scores, AzBio Sentence pure tone thresholds, localization,...
Abstract Introduction: Patients with locally advanced head and neck squamous cell carcinoma (LA-HNSCC) have high risk of disease progression death after standard concurrent chemoradiotherapy (CCRT). We are conducting a prospective trial to investigate the efficacy combining immune checkpoint blockade (ICB) PARP inhibition prior following CCRT. Here we report feasibility utilizing pre- post-induction CT simulations assess early imaging response in patients treated on trial. Methods:...
Objective To compare primary total laryngectomy (TL) versus salvage TL and analyze the functional outcomes, complications, recurrence rates, survival. Study Design Case series with chart review. Setting Tertiary care center. Subjects Methods Fifteen‐year retrospective analysis of 208 patients laryngeal squamous cell carcinoma treated by was completed. Outcome measures included survival, swallowing rehabilitation, speech assessment comorbidity. Survival estimates were analyzed Kaplan‐Meier...
To evaluate the association between signal changes during intraoperative audiologic monitoring and postoperative audiometric outcome in patients undergoing vestibular schwannoma (VS) resection via middle cranial fossa (MCF) approach.Retrospective chart review.Academic tertiary referral center.One hundred twenty-six consecutive (mean age 48.6 yrs, range 16-67; mean tumor size 9.9 mm, 1.8-18.9 mm) who underwent MCF VS resection.Intraoperative using auditory brainstem response (ABR) direct...
Survival outcomes for advanced non-melanoma skin cancers of the head and neck treated with surgical resection are not well described in literature. We aimed to describe T3 T4 cutaneoous squamous cell carcinoma or at 1 tertiary academic medical center.We analyzed a retrospective cohort patients diagnosed cutaneous (SCC) from 2005 2016 definitive resection. were examined using Kaplan-Meier analysis, multivariate analysis was completed Cox proportional hazard model.Forty-three met inclusion...
Objective To analyze the clinicodemographic characteristics and treatment outcomes of patients receiving postoperative radiation therapy (PORT) at a different facility rather than initial surgical for head neck cancer. Study Design: Retrospective cohort analysis. Methods Utilizing National Cancer Data Base, 2004 to 2015, with diagnosis oral cavity/oropharyngeal, hypopharyngeal, laryngeal squamous cell carcinoma were studied. Multivariate analysis was completed multivariate regression Cox...
The Health Information Technology for Economic and Clinical (HITECH) Act of 2009 aims to expand the use electronic health records by offering financial incentives physicians fully adopt implement them. We surveyed Florida who deliver care Medicaid participants identify their interest in participating incentive program. More than 60 percent all respondents expressed applying incentives; those already using record systems, 86 intend apply funding. This relatively high proportion creates...
Examine the role of elective neck dissection (END) and adjuvant radiotherapy (RT) in early-stage clinically N0 parotid mucoepidermoid carcinoma (MEC).The study is a retrospective analysis National Cancer Database, 2004-2016. The population included adult patients with MEC who underwent parotidectomy.A total 1233 were included. Histopathology demonstrated well, moderately, poorly differentiated 47.12%, 39.98%, 12.90% time, respectively. END was performed 78.67% patients, resulting nodal...
Objectives To examine clinical profile and outcomes of elderly patients (65‐90 years) undergoing head neck surgeries in the United States. Study Design A retrospective cross‐sectional analysis. Setting The Nationwide Readmissions Database, 2010 to 2015. Subjects Methods Adult (≥18 who underwent surgeries. Analysis included χ 2 test logistic Results total 113,602 32,580 <65 ≥65 years old, respectively, were included. Patients old more likely have multiple comorbidities (62.8% vs 32.6%, P...
Objectives Examine the prevalence and risk of metastasis in thyroid cancers management outcomes. Study design Retrospective analysis National Cancer Database, 2004–2014. Methods The study population included adult (≥ 18 years) patients with cancer. Analysis multivariate logistic regression Cox hazard ratio modeling. Results A total 152,979 were included. Distant was reported 1,867 (1.22%) patients. distribution metastatic cases based on pathology tumor size as follows descending order:...
Objective: To evaluate the relationship between radiographic fundal fluid cap in lateral internal auditory canal, preoperative clinical characteristics, and postoperative outcomes patients with vestibular schwannoma who underwent microsurgical excision. Study Design: Retrospective chart review. Setting: Academic tertiary referral center. Patients: Thirty-six consecutive (mean age 49.4 yr [range 29–74]) Interventions: Microsurgical Main Outcome Measures: Linear size tumor calculated using...
Red blood cell distribution width (RDW), a reported biomarker for morbidity and mortality in chronic disease following certain surgeries, has not been well-studied head neck cancer patients. The aim of the study was to examine association RDW with postoperative complications survival among patients who underwent primary or salvage laryngectomy.We analyzed retrospective case series diagnosed squamous carcinoma larynx treated total laryngectomy. Survival outcomes were examined using...
Mesenchymal tumors harboring GLI1 gene fusions are a rare new entity that typically occur in the head and neck region of young to middle aged adults, with particular predilection for tongue. We report herein case epithelioid mesenchymal tumor PTCH1-GLI1 fusion right submental an 82-year-old male never smoker. Ultrasound-guided fine needle aspiration (FNA) concomitant core biopsy was performed. Cytology smears revealed hypercellular, monotonous aspirate comprised plasmacytoid cells round...
Abstract Background To analyze demographic and socioeconomic factors that influence patients' decisions to decline treatment for head neck squamous cell carcinoma (SCC). Methods Retrospective cohort analysis utilizing the National Cancer Data Base of patients with oral cavity/oropharyngeal, hypopharyngeal, laryngeal SCC. Results A total 166 204 were included, which 689 declined all treatment. Among early‐stage (I‐II) patients, Charlson/Deyo score ≥ 3, hypopharyngeal cancer, no insurance or...
Abstract Background To analyze the characteristics and survival patterns of patients with head neck squamous cell carcinoma (SCC) who received palliative treatment during their first course treatment. Methods Cohort analysis utilizing National Cancer Data Base (NCDB) a diagnosis oral cavity/oropharyngeal, hypopharyngeal, laryngeal SCC. Statistical included multivariate logistic regression Cox Hazard ratio modeling, Kaplan‐Meier analysis. Results 165 081 were included, which 2747 Patients...
Objective Under the Affordable Care Act (ACA), Medicaid expansion became effective in states that have adopted it. We aim to examine its impact on head and neck cancers. Methods A retrospective study utilizes Surveillance, Epidemiology, End Results database, 2010–2016. Study population included patients with squamous cell carcinoma (HNSCC), differentiated thyroid carcinoma, cutaneous melanoma. The objective is disease‐specific survival before after expansion. In expansion, ratio of Medicaid:...
Objective To evaluate the postoperative facial nerve dysfunction, audiometric outcomes, and long‐term quality‐of‐life outcomes of patients with idiopathic recurrent paralysis (RFP) after middle cranial fossa (MCF) microsurgical decompression. Methods Retrospective chart analysis 11 (mean age 37.0 years, range 5 to 67) at an academic tertiary referral center who underwent MCF Data included evaluation pre‐ House‐Brackmann (HB) score, pure‐tone average (PTA), pre‐and word recognition scores...