A5085074957- Schizophrenia research and treatment
- Meta-analysis and systematic reviews
- Health Systems, Economic Evaluations, Quality of Life
- Healthcare Decision-Making and Restraints
- Mental Health and Psychiatry
- Psychiatric care and mental health services
- Mental Health Treatment and Access
- Bipolar Disorder and Treatment
- Electroconvulsive Therapy Studies
- Digital Mental Health Interventions
- Treatment of Major Depression
- Pharmaceutical studies and practices
- Epilepsy research and treatment
- Psychopathy, Forensic Psychiatry, Sexual Offending
- Health and Medical Research Impacts
- Clinical practice guidelines implementation
- Personality Disorders and Psychopathology
- Health Sciences Research and Education
- Primary Care and Health Outcomes
- Substance Abuse Treatment and Outcomes
- Opioid Use Disorder Treatment
- Mental Health Research Topics
- Child and Adolescent Psychosocial and Emotional Development
- Biomedical Text Mining and Ontologies
- Pharmaceutical Practices and Patient Outcomes
University of Nottingham
2016-2025
Institute of Mental Health
2015-2025
Cochrane
2013-2025
Acadia University
2022
Nottinghamshire Healthcare NHS Foundation Trust
2017
Queen's University
2016
Kingston Health Sciences Centre
2016
University of Central Lancashire
2016
Keele University
2016
Creative Research Enterprises (United States)
2016
Background A recent review suggested an association between using unpublished scales in clinical trials and finding significant results. Aims To determine whether such existed schizophrenia trials. Method Three hundred were randomly selected from the Cochrane Schizophrenia Group's Register. All comparisons treatment groups control rating identified. The publication status of each scale was determined claims a effect recorded. Results Trials more likely to report that superior when used make...
Aims and Method To estimate the proportion of attrition at which results drug trials for people with schizophrenia lose enough credibility to become mistrusted by relevant groups stakeholders. A piloted questionnaire was sent 128 local clinicians, 100 researchers 104 service users carers. Results We received biggest number responses from user carer group ( n =81, 76%); 43% clinicians 32% responded. All three suggested that follow-up rate a 12-week trial should be around 70–75% credible....
<h3>Abstract</h3> <b>Objective</b> To provide a comprehensive survey of the content and quality intervention studies relevant to treatment schizophrenia. <b>Design</b> Data were extracted from 2000 trials on Cochrane Schizophrenia Group9s register. <b>Main outcome measures</b> Type date publication, country origin, language, size study, setting, participant group, interventions, outcomes, study. <b>Results</b> Hospital based drug undertaken in United States dominant sample (54%). Generally,...
Background The pharmacological management of violence in people with psychiatric disorders is under-researched. Aims To compare interventions commonly used for controlling agitation or serious disorders. Method We randomised 200 to receive intramuscular lorazepam (4 mg) haloperidol (10 plus promethazine (25–50 mg mix). Results At blinded assessments 4 h later (99.5% follow-up), equal numbers both groups (96%) were tranquil asleep. However, 76% given the haloperidol-promethazine mix asleep...
<b>Objective</b> To determine whether haloperidol alone results in swifter and safer tranquillisation sedation than plus promethazine. <b>Design</b> Pragmatic randomised open trial (January-July 2004). <b>Setting</b> Psychiatric emergency room, Rio de Janeiro, Brazil. <b>Participants</b> 316 patients who needed urgent intramuscular because of agitation, dangerous behaviour, or both. <b>Interventions</b> Open treatment with 5-10 mg promethazine up to 50 mg; doses were at the discretion...
Valid reviews of the effects mental health care depend on identifying as high a proportion possible relevant randomized controlled trials (RCTs). To investigate sensitivity and precision both MEDLINE hand-searching for RCTs in health, 12 journals specializing indexed by National Library Medicine (NLM) were searched years 1971, 1976, 1981, 1986 1991. The hand-search was 94% (95% Confidence Interval (CI) 93-95%), but it had only 7% (CI 6-8%). optimal search 52% 48-56%) 59% 55-63%). Of reports...