A5048539825- Carbon and Quantum Dots Applications
- SARS-CoV-2 and COVID-19 Research
- COVID-19 Clinical Research Studies
- Nanocluster Synthesis and Applications
- Nanoplatforms for cancer theranostics
- Catalytic Cross-Coupling Reactions
- Graphene and Nanomaterials Applications
- Advanced biosensing and bioanalysis techniques
- Advanced Drug Delivery Systems
- Radiopharmaceutical Chemistry and Applications
- Bacteriophages and microbial interactions
- Quantum Dots Synthesis And Properties
- Artificial Intelligence in Healthcare and Education
- Optical Coherence Tomography Applications
- Photoacoustic and Ultrasonic Imaging
- RNA Interference and Gene Delivery
- Infectious Encephalopathies and Encephalitis
- Pharmacological Receptor Mechanisms and Effects
- Nanoparticle-Based Drug Delivery
- Long-Term Effects of COVID-19
- COVID-19 diagnosis using AI
- Dendrimers and Hyperbranched Polymers
- Dental Research and COVID-19
- Peptidase Inhibition and Analysis
- Polymer Surface Interaction Studies
Zanjan University of Medical Sciences
2023-2024
Shahid Beheshti University of Medical Sciences
2024
Tehran University of Medical Sciences
2019-2022
Iran University of Medical Sciences
2020-2021
University of Zanjan
2021
University of Nebraska Medical Center
2020
Islamic Azad University, Tehran
2020
Institute for Advanced Studies in Basic Sciences
2015-2019
Abstract In this report, Fe 3 O 4 nanoparticles are modified for the first time with graphene quantum dots (GQD) and used stabilization of PdCu bimetallic nanoparticles. The new magnetic compound, PdCu@GQD@Fe , is characterized by different methods such as SEM, high‐resolution (HR)‐TEM, energy‐dispersive X‐ray spectroscopy (EDS) mapping, XRD, photoelectron (XPS). This material applied an efficient catalyst Sonogashira reaction aryl iodides, bromides, chlorides in toluene or N...
Driven by regulatory authorities and the ever-growing demands from industry, various artificial tissue models have been developed. Nevertheless, there is no model to date that capable of mimicking biomechanical properties skin whilst exhibiting hydrophilicity/hydrophobicity layers. As a proof-of-concept study, surrogates based on gel silicone are fabricated for evaluation microneedle penetration, drug diffusion, photothermal activity, ultrasound bioimaging. The layer aims imitate stratum...
Abstract Magnetic Fe 3 O 4 nanoparticles (NPs) functionalized with carbon dots (C‐dots) that contain carboxylic acid and hydroxyl groups were synthesized successfully used for the reduction of Pd II formation NPs. The new material was characterized by SEM, TEM, energy‐dispersive spectroscopy, solid UV vibrating sample magnetometry, XRD, X‐ray photoelectron spectroscopy as a very efficient catalyst in Suzuki–Miyaura cross‐coupling reaction aryl bromides chlorides arylboronic acids aqueous...
Nanotechnology-based drug delivery platforms have emerged as one of the promising approaches for diagnosis and treatment cancers. Furthermore, significant advancements been achieved in development nanoparticle-antibody conjugates applications tumor imaging immunoassays. Without a doubt, diagnostic insight garnered from these nanoprobes will prove invaluable determining rational therapeutic strategies. In current experiment, we developed breast cancer probe utilizing graphene quantum dots,...
Hydrocortisone, a commonly used anti-inflammatory drug, has limited aqueous solubility and several side effects. To address this challenge, as proof-of-concept, article demonstrates the development of controlled-release drug delivery system (DDS) for hydrocortisone using chitosan-grafted poly(N-vinylcaprolactam) (CS-g-PNVCL)-coated core–shell Fe3O4@SiO2 nanoformulations (NFs). Reported magnetic nanoparticles (NPs) were synthesized modified with silica, PNVCL, CS precursors to enhance...
Abstract Skin lesions, including skin bacterial abscesses, have become one of the most important health challenges and usually need systemic high‐dose antibiotics. Therefore, it is particular importance to develop novel approaches for treating this ever‐growing challenge human health. To address challenge, herein a copper nanostructure developed giving combined photothermal chemodynamic therapies focal infection treatment. The Cu‐based nanostructures with intrinsic catalytic properties are...
Tissue Models In article number 2210034, Pooyan Makvandi, Virgilio Mattoli, and co-workers report the fabrication of tissue substitutes for ex vivo human tissues animals. models based on hydrogel/silicon films are prepared different applications in biomedical sector. These customized surrogates can be employed as a platform to evaluate ability microneedle insertion, diffusion drugs, activity photothermal agents, performance ultrasound bioimaging.
Even today, technetium-99m is a radionuclide choice for diagnostic in nuclear medicine. The unique chemical and physical properties of make it suitable as an available many centers. In this study, we examined the potential CQD reducing agent MDP kit. Citric acid-derived was synthesized confirmed by FT-IR, TEM, UV-Vis, XPS, surface analysis. No cytotoxicity observed MTT assay. They were fluorescence microscopy. kit prepared evaluating different parameters that affect radiolabeling yield,...
The development of a high-performance biosensor for potassium ion (K <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">+</sup> ) analysis is desirable clinical diagnostics. In the present study, sensitive and selective has been presented K determination using G-rich ssDNA as recognition tool. A fluorimetric assay based on intermolecular G-quadruplex was introduced metal sulfide (CoS CuS) nanosheets quenchers carbon dots (CDs) fluorescence probes...
Dopamine is one of the most important neurotransmitters released by neurons in central nervous system, and a variety neurological illnesses mental disorders are associated with impairments secretion functionality dopamine. Dopamine, depending on type receptors, can act as stimulant or an inhibitor. In this study, dendrimer-conjugated dopamine was utilized chelating agent for Technetium-99m to investigate organ distribution compound vivo using single-photon emission computed tomography...
Discovering new chemotherapy drugs and techniques with the least side effects is one of most important challenging issues in recent years worldwide. Chlorambucil an anticancer drug that still commonly used as a primary treatment treating some cancers, but it can cause effects.In this study, we decided to use chitosan carrier enhance uptake chlorambucil reduce toxicity drug.After producing nanoconjugate compound analysing its structure by FTIR, DLS AFM analysis, investigated therapeutic...
Studies of coronavirus disease 2019 (COVID-19) as a current global health problem shown the initial plasma levels most pro-inflammatory cytokines increased during infection, which leads to patient countless complications. Previous studies also demonstrated that metronidazole (MTZ) administration reduced related and improved treatment in patients. However, effect this drug on has not been determined. In present study, interaction MTZ with was investigated using molecular docking one principal...
COVID-19, a pandemic affecting virus, which is caused by the current SARS-CoV2 coronavirus. The present research performed on anti virus and immune-modulating therapies. Cytokine storms are toxic drivers mortality various human viral infections. In addition, intensity was linked to an elevated risk of acute respiratory failure, myocardial injury, in SARS-CoV-2-infected patients. Janus kinase (JAK) therapeutic inhibitor class showed significant clinical benefits anti-inflammatory anti-viral...
Introduction . Breast cancer is the leading cause of mortality for women, and effort being made to provide an agent which has both imaging therapeutic effects (theranostics) can improve survival, economic burden, outcomes. Methods In this research, first time, we introduce a new magnetophotoluminescent quantum dot (Mn‐Si‐QD) capable DOX loading. Mn‐Si‐QD was synthesized evaluated by FT‐IR, UV‐Vis, fluorescence, SEM, TEM. The impacts various factors such as reaction time temperature were...
Abstract The most crucial role of granulocyte colony‐stimulating factor (G‐CSF) in the body is to increase strength immune system. In recent years, research on use nanoparticles pharmaceuticals has been considered, which have for drug‐loading purposes. this study, a novel G‐CSF conjugated dendrimer was synthesized and characterized using different techniques. vitro cytotoxicity assessed A549 L929 cells, while abnormal toxicity studied mice. vivo biological activities were NFS60 cells rats,...
Studies of coronavirus disease 2019 (COVID-19) as a current global health problem shown the initial plasma levels most pro-inflammatory cytokines increased during infection, which leads to patient countless complications. Previous studies also demonstrated that metronidazole (MTZ) administration reduced related and improved treatment in patients. However, effect this drug on has not been determined. In present study, interaction MTZ with was investigated using molecular docking one principal...
Studies of coronavirus disease 2019 (COVID-19) as a current global health problem shown the initial plasma levels most pro-inflammatory cytokines increased during infection, which leads to patient countless complications. Previous studies also demonstrated that metronidazole (MTZ) administration reduced related and improved treatment in patients. However, effect this drug on has not been determined. In present study, interaction MTZ with was investigated using molecular docking one principal...
COVID-19, a pandemic affecting virus, which is caused by the current SARS-CoV2 coronavirus. The present research performed on anti virus and immune-modulating therapies. Cytokine storms are toxic drivers mortality various human viral infections. In addition, intensity was linked to an elevated risk of acute respiratory failure, myocardial injury, in SARS-CoV-2-infected patients. Janus kinase (JAK) therapeutic inhibitor class showed significant clinical benefits anti-inflammatory anti-viral...
Dental journal editors, grant providers, research managers, educational planners, and clinical professionals could direct more attention to artificial intelligence machine learning as a rapid, effective inexpensive tool solve complicated problems.
Studies of coronavirus disease 2019 (COVID-19) as a current global health problem shown the initial plasma levels most pro-inflammatory cytokines increased during infection, which leads to patient countless complications. Previous studies also demonstrated that metronidazole (MTZ) administration reduced related and improved treatment in patients. However, effect this drug on has not been determined. In present study, interaction MTZ with was investigated using molecular docking one principal...