A5075846618- Reproductive biology and impacts on aquatic species
- Aquaculture Nutrition and Growth
- Estrogen and related hormone effects
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Physiological and biochemical adaptations
- Aquaculture disease management and microbiota
- Fish Ecology and Management Studies
- Effects and risks of endocrine disrupting chemicals
- Neonatal and fetal brain pathology
- Acute Myeloid Leukemia Research
- Child Nutrition and Water Access
- Neuroendocrine regulation and behavior
- Anesthesia and Neurotoxicity Research
- Biochemical effects in animals
- Mitochondrial Function and Pathology
- Phagocytosis and Immune Regulation
- Birth, Development, and Health
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Reproductive Biology and Fertility
Banaras Hindu University
2007-2022
Agricultural Research Organization
2018
Oregon Health & Science University
2015
Mutations in the calreticulin gene ( CALR ) were recently identified approximately 70–80% of patients with JAK2‐ V617F‐negative essential thrombocytosis and primary myelofibrosis. All frameshift mutations generate a recurring novel C‐terminus. Here we provide evidence that mutant does not accumulate efficiently cells is abnormally enriched nucleus extracellular space compared to wildtype calreticulin. The main determinant these findings loss calcium‐binding KDEL domains. Expression type I...
Nile tilapia (Oreochromis niloticus) is the world's most widely cultured fish species. Therefore, its nutritional physiology of great interest from an aquaculture perspective. Studies conducted on several species, including tilapia, demonstrated beneficial effects dietary salt supplementation growth; however, mechanism behind these still not fully understood. The intestine a complex system, with functions, such as nutrient absorption, ion equilibrium and acid-base balance that are tightly...
Estradiol-17beta (E2) maintains high cAMP levels and meiotic arrest in zebrafish oocytes through activation of G protein-coupled estrogen receptor (GPER). The catecholestrogen 2-hydroxyestradiol-17beta (2-OHE2) has an opposite effect to that E2 on oocyte maturation (OM) Indian catfish oocytes. We tested the hypothesis 2-OHE2 is produced ovaries promotes resumption meiosis its action as a GPER antagonist. Ovarian production by estrogen-2-hydroxylase (EH) was up-regulated gonadotropin...
The synthesis of bioactive steroids is catalyzed by an array enzymes diverse properties and actions. In the present study, seasonal dynamics kinetics key steroidogenic enzymes, 17α-hydroxylase (Cyp17a), 3β-hydroxysteroid dehydrogenase (Hsd3b), 20α-hydroxysteroid (Hsd20a) 20β-hydroxysteroid (Hsd20b) were investigated in female catfish Heteropneustes fossilis. Further, effects estrogen metabolite 2-hydroxyestradiol-17β (2-OHE2) human chorionic gonadotropin (hCG) on activities above cytochrome...