A5004981925- Aquaculture Nutrition and Growth
- Physiological and biochemical adaptations
- Aquaculture disease management and microbiota
- Advanced biosensing and bioanalysis techniques
- Advanced Proteomics Techniques and Applications
- Protein Hydrolysis and Bioactive Peptides
- Reproductive biology and impacts on aquatic species
- Animal Genetics and Reproduction
- Child Nutrition and Water Access
- Biochemical Analysis and Sensing Techniques
- Liver Disease and Transplantation
- Drug Transport and Resistance Mechanisms
- Cardiovascular Syncope and Autonomic Disorders
- Electrolyte and hormonal disorders
- MicroRNA in disease regulation
- Metabolomics and Mass Spectrometry Studies
Agricultural Research Organization
2017-2024
Hebrew University of Jerusalem
2017-2024
The peptide transporter (PepT) systems are well-known for their importance to protein absorption in all vertebrate species. These symporters use H+ gradient at the apical membrane of intestinal epithelial cells mediate small peptides. In fish, intestine is a multifunctional organ, involved osmoregulation, acid-base regulation, and nutrient absorption. Therefore, we expected environmental stimuli affect We examined effect three factors; salinity, pH feeding, on expression, activity...
Nile tilapia (Oreochromis niloticus) is the world's most widely cultured fish species. Therefore, its nutritional physiology of great interest from an aquaculture perspective. Studies conducted on several species, including tilapia, demonstrated beneficial effects dietary salt supplementation growth; however, mechanism behind these still not fully understood. The intestine a complex system, with functions, such as nutrient absorption, ion equilibrium and acid-base balance that are tightly...
All organisms encounter environmental changes that lead to physiological adjustments could drive evolutionary adaptations. The ability adjust performance in order cope with depends on the organism's plasticity. These can be reflected behavioral, physiological, and molecular changes, which interact affect each other. Deciphering role of will help understand how multiple levels biological organization are synchronized during Transmembrane transporters, facilitate a cell's interaction its...
A data-independent acquisition (DIA) assay library for targeted quantitation of thousands Oreochromis niloticus gill proteins using a label- and gel-free workflow was generated used to compare protein mRNA abundances. This approach complimentary rather than redundant data 1899 unique genes in gills tilapia acclimated freshwater brackish water. Functional enrichment analyses identified mitochondrial energy metabolism, serine protease immunity-related functions, cytoskeleton/ extracellular...
Abstract Interactions of organisms with their environment are complex and environmental regulation at different levels biological organization is often nonlinear. Therefore, the genotype to phenotype continuum requires study multiple organization. While studies transcriptome now common for many species, quantitative effects on proteomes needed. Here we report generation a data‐independent acquisition (DIA) assay library that enables simultaneous targeted proteomics thousands Oreochromis...
Fish larvae differ greatly from the adult form in their morphology and organ functionality. The functionality of gastrointestinal tract depends on expression various pumps, transporters, channels responsible for feed digestion nutrients absorption. During larval period, develops a simple closed tube, into its complex with differentiated segments, crypts villi, as found adult. In this study, we characterized three peptide transporters (PepT1a, PepT1b, PepT2) Mozambique tilapia (Oreochromis...
Interactions of organisms with their environment are complex and environmental regulation at different levels biological organization is often non-linear. Therefore, the genotype to phenotype continuum requires study multiple organization. While studies transcriptome now common for many species, quantitative effects on proteomes needed. Here we report generation a data-independent acquisition (DIA) assay library that enables simultaneous targeted proteomics thousands Oreochromis niloticus...
Abstract Nutrient absorption through the skin and gills into organisms’ tissues has been documented in several aquatic invertebrates from different phyla. However, actual mechanism is still unknown. In teleost fish, as all jawed vertebrates, intestinal considered sole source of nutrients. The proton-dependent peptide transporters (PepT) slc15a gene family are only known for cellular di- tri-peptides within animal kingdom. this study, we explored expression localization PepT2 Mozambique...
All organisms encounter environmental changes that lead to physiological adjustments and drive evolutionary adaptations. These, in turn, induce behavioral, molecular affect each other. Deciphering the role of will help understand how multiple levels biological organization are synchronized during Transmembrane transporters prime targets for studies effects, as they facilitate ability cells interact with external surrounding. Fish subjected fluctuations factors their aquatic surrounding...
Chronic salinity stress is likely to have significant impacts on organismal performance, especially near the upper bounds of Critical Salinity maximum (CSmax), “zone resistance”. Some euryhaline fish species maintain stable internal osmolality over great ranges, while close relatives tolerate much narrower ranges. Greater tolerance ranges also been linked reduced growth under optimum conditions. For example, breeding for improved rates in tilapia Oreochromis niloticus has inadvertently...