A5026091329- Aortic Disease and Treatment Approaches
- Aortic aneurysm repair treatments
- Cardiac Valve Diseases and Treatments
- Fish Biology and Ecology Studies
- Connective tissue disorders research
- Infectious Aortic and Vascular Conditions
- Marine and fisheries research
- Cardiac, Anesthesia and Surgical Outcomes
- Cardiac Structural Anomalies and Repair
- Infective Endocarditis Diagnosis and Management
- Congenital Heart Disease Studies
- Aquaculture Nutrition and Growth
- Cardiovascular Issues in Pregnancy
- Radioactive contamination and transfer
- Elasticity and Material Modeling
- Crustacean biology and ecology
- Radioactivity and Radon Measurements
- Cardiac and Coronary Surgery Techniques
- Identification and Quantification in Food
- Fisheries and Aquaculture Studies
- Marine Bivalve and Aquaculture Studies
- Nuclear and radioactivity studies
- Advanced Glycation End Products research
- Fish Ecology and Management Studies
- Hydrocarbon exploration and reservoir analysis
Yale New Haven Hospital
2016-2025
Yale University
2016-2025
Pakistan Institute of Medical Sciences
2024
RELX Group (United States)
2023
University of New Haven
2012-2023
Faculty of 1000 (United States)
2023
Quaid-i-Azam University
2016-2023
Bahria University
2023
Shelton History Center
2022-2023
New York Proton Center
2023
Thoracic aortic aneurysms, with an estimated prevalence in the general population of 1%, are potentially lethal, via rupture or dissection. Over prior two decades, there has been exponential increase our understanding genetics thoracic aneurysm and/or dissection (TAAD). To date, 30 genes have shown to be associated development TAAD and ∼30% individuals nonsyndromic familial a pathogenic mutation one these genes. This review represents authors' yearly update summarizing TAAD, including...
This study aims to outline the 'true' natural history of ascending thoracic aortic aneurysm (ATAA) based on a cohort patients not undergoing surgical intervention.The outcomes, risk factors, and growth rates 964 unoperated ATAA were investigated, over median follow-up 7.9 (maximum 34) years. The primary endpoint was adverse events (AAE), including dissection, rupture, death. At sizes 3.5-3.9, 4.0-4.4, 4.5-4.9, 5.0-5.4, 5.5-5.9, ≥6.0 cm, average yearly AAE 0.2%, 0.3%, 1.4%, 2.0%, 3.5%,...
Abstract Thoracic aortic aneurysm is a typically silent disease characterized by lethal natural history. Since the discovery of familial nature thoracic and dissection (TAAD) almost 2 decades ago, our understanding genetics this disorder has undergone transformative amplification. To date, at least 37 TAAD-causing genes have been identified an estimated 30% patients with nonsyndromic TAAD harbor pathogenic mutation in one these genes. In review, we present yearly update summarizing...
<b><i>Background:</i></b> Multiple studies have quantified the relationship between aortic size and risk of dissection. However, these estimated dissection without accounting for any increase in from process itself. <b><i>Objectives:</i></b> This study aims to compare before after evaluate change consequent <b><i>Methods:</i></b> Fifty-five consecutive patients (29 type A; 26 B) with incidental imaging prior were...
Background: Cardiovascular complications account for a significant proportion of the shortened lifespan Marfan syndrome (MFS) patients, with aortic dissection being most dreadful complication. The root dilates initially in MFS and given its important hemodynamic role, this can lead to regurgitation poses substantial risk dissection. This study seeks evaluate natural history aneurysms focus on growth rates correlation diameter developing complications. Methods: Seventy-eight patients...
Background Data from the International Registry of Acute Aortic Dissection indicate that guideline criterion 5.5 cm for ascending aortic intervention misses many dissections occurring at smaller dimensions. Furthermore, studies natural behavior have generally treated root and aorta as 1 unit despite embryological, anatomical, functional differences. This study aims to disentangle histories aforementioned segments, allowing define specific criteria segments aorta. Methods Results Diameters...
This study is to establish prediction tools for in-hospital rupture of type A aortic dissection (TAAD) patients, better guide emergency surgical triage and patient counselling.We retrospectively evaluated 1,133 consecutive patients with TAAD from January 2010 December 2016. The population was divided into training testing datasets in a 70:30 ratio further analysis using Random Forest.The Forest classification model developed the dataset 16 variables were confirmed as 'important': age, BMI,...
Machine learning (ML) has experienced a revolutionary decade with advances across many disciplines. We seek to understand how recent in ML are going specifically influence the practice of surgery future particular focus on thoracic surgery.Review relevant literature both technical and clinical domains.ML is technology that promises change way practiced near future. Spurred by an advance computing power volume data produced healthcare, shown remarkable ability master tasks had once been...
To determine the frequency and types of dermatological conditions including sexually-transmitted infections (STIs) within lesbian, gay, bisexual, transgender, queer (LGBTQ) communities. A cross-sectional survey. Place Duration Study: Department Dermatology, Services Hospital, Lahore, Pakistan, from 19 April to 20 May 2023. The survey was conducted on members LGBTQ community registered with Fountain House, aged 18 years above. Data demographics, sexual orientation, hormone use,...