A5102020696- Nitric Oxide and Endothelin Effects
- Medical Imaging Techniques and Applications
- Renin-Angiotensin System Studies
- Anesthesia and Sedative Agents
- Neuropeptides and Animal Physiology
- Cancer, Hypoxia, and Metabolism
- Hormonal Regulation and Hypertension
- Electrolyte and hormonal disorders
- Lung Cancer Treatments and Mutations
- Venomous Animal Envenomation and Studies
- Blood Pressure and Hypertension Studies
- Glioma Diagnosis and Treatment
- Intracranial Aneurysms: Treatment and Complications
- Phenothiazines and Benzothiazines Synthesis and Activities
- Traumatic Brain Injury and Neurovascular Disturbances
- Chemical synthesis and alkaloids
- Lung Cancer Diagnosis and Treatment
- Pulmonary Hypertension Research and Treatments
- Healthcare and Venom Research
- Anesthesia and Neurotoxicity Research
- Receptor Mechanisms and Signaling
- Advanced MRI Techniques and Applications
- Radiopharmaceutical Chemistry and Applications
- Neurological disorders and treatments
- Cardiovascular Issues in Pregnancy
Fujita Health University
2010-2021
Tokyo University of Marine Science and Technology
2019
Oita University
2013-2014
RIKEN Center for Computational Science
2013
Toyota Memorial Hospital
2011
Tottori University
2005-2006
Kyushu University Hospital
2006
Kyushu University
2001-2005
Kumamoto University
2004
Mitsubishi Group (Japan)
2003
Summary: We examined the possible involvement of endogenous angiotensin II (ANG II) in norepinephrine (NE) overflow and antidiuresis induced by renal nerve stimulation (RNS). RNS at a frequency 0.5–2.0 Hz, which did not influence hemodynamics, produced significant reductions urine flow urinary excretion sodium, elevations NE secretion rate (NESR) renin (RSR). Intrarenal arterial (i.r.a.) in-fusion phentolamine (10 μg/kg/min) abolished RNS-induced antidiuresis. In dogs receiving captopril (15...
1. Rho-associated coiled-coil forming protein serine/threonine kinase (ROCK) is involved in the development of tumour metastasis. Wf-536, (+)-(R)-4-(1-Aminoethyl)-N-(4-pyridyl) benzamide monohydrochloride, a novel inhibitor ROCK, inhibits metastasis some animal models. To metastasise, cells have to disturb tight intercellular junctions and basement membrane matrix host tissue, which, respectively, create an barrier extracellular membrane. clarify mechanism Wf-536 inhibition metastasis, we...
Hypoperfusion in the posterior cingulate cortex is thought to be useful for early diagnosis of dementia Alzheimer type (DAT). In present study, we compared incidence hypoperfusion patients with Alzheimer's disease (AD), senile (SDAT), and other types dementia, as evaluated by three-dimensional stereotactic surface projection (3D-SSP) imaging. The subjects were 20 AD patients, SDAT 13 frontotemporal 3 patients. A SPECT study was performed 5 minutes after injection 740 MBq technetium-99m...
The aims of this study were to examine the enhancing effects aloe-emodin anthrone (AEA) on colonic membrane permeability water-soluble and poorly permeable compounds clarify mechanism permeation-enhancing activity AEA. AEA was estimated from changes in coefficient 5(6)-carboxyfluorescein (CF) rat mucosa using a Ussing-type chamber. Various inhibitors used investigate action structural change cytotoxicity intestinal evaluated by measuring electrical resistance (R(m)) lactate dehydrogenase...