M. De Luca
A5103130711- Astrophysics and Star Formation Studies
- Liver Disease Diagnosis and Treatment
- Stellar, planetary, and galactic studies
- Molecular Spectroscopy and Structure
- Atmospheric Ozone and Climate
- Hepatocellular Carcinoma Treatment and Prognosis
- Liver Disease and Transplantation
- Hepatitis C virus research
- Spectroscopy and Laser Applications
- Astro and Planetary Science
- Hepatitis B Virus Studies
- Astronomy and Astrophysical Research
- MRI in cancer diagnosis
- Atomic and Molecular Physics
- Ionosphere and magnetosphere dynamics
- Radiomics and Machine Learning in Medical Imaging
- Cancer, Lipids, and Metabolism
- Galaxies: Formation, Evolution, Phenomena
- HIV/AIDS drug development and treatment
- Multiple and Secondary Primary Cancers
- Astronomical Observations and Instrumentation
- Migraine and Headache Studies
- Nutrition and Health in Aging
- Advanced MRI Techniques and Applications
- Organ Transplantation Techniques and Outcomes
Fatebenefratelli Hospital
2011-2025
University of Chieti-Pescara
2024
Ospedale Antonio Cardarelli
2017-2024
University of Messina
2021
Centre National de la Recherche Scientifique
2009-2019
Laboratoire d’Etudes du Rayonnement et de la Matière en Astrophysique et Atmosphères
2009-2019
University of Campania "Luigi Vanvitelli"
2016
École Normale Supérieure - PSL
2009-2014
Sorbonne Université
2010-2014
Université Paris Cité
2014
Aims. In this paper the calibration and in-orbit performance of Heterodyne Instrument for Far-Infrared (HIFI) is described.
We report the detection of absorption lines by reactive ions OH<sup>+<sup/>, H<sub>2<sub/>O<sup>+<sup/>and H<sub>3<sub/>O<sup>+<sup/> along line sight to submillimeter continuum source G10.6–0.4 (W31C). used <i>Herschel<i/> HIFI instrument in dual beam switch mode observe ground state rotational transitions OH<sup>+<sup/> at 971 GHz, H<sub>2<sub/>O<sup>+<sup/> 1115 and 607 984 GHz. The resultant spectra show deep over a broad velocity range that originates interstellar matter as well...
We report the detection of absorption by interstellar hydroxyl cations and water cations, along sight-line to bright continuum source W49N. have used Herschel's HIFI instrument, in dual beam switch mode, observe 972 GHz N = 1 - 0 transition OH+ 1115 1(11) 0(00) ortho-H2O+. The resultant spectra show ortho-H2O+, strong OH+, foreground material at velocities range 70 km/s with respect local standard rest. inferred OH+/H2O+ abundance ratio ranges from ~ 3 15, implying that observed arises...
We report observations of three rotational transitions molecular oxygen (O2) in emission from the H2 Peak 1 position vibrationally excited hydrogen Orion. observed 487 GHz, 774 and 1121 GHz lines using HIFI on Herschel Space Observatory, having velocities 11 km s-1 to 12 widths 3 s-1. The beam-averaged column density is N(O2) = 6.5\times1016 cm-2, assuming that source has an equal beam filling factor for all (beam 44, 28, 19"), relative line intensities imply a kinetic temperature between 65...
Aims. The HIFI instrument onboard Herschel has allowed high spectral resolution and sensitive observations of ground-state transi- tions three molecular ions: the methylidyne cation CH+, its isotopologue 13CH+, sulfanylium SH+. Because their unique chemical properties, a comparative analysis these cations provides essential clues to link between chemistry dynamics diffuse interstellar medium. Methods. SH+ lines are observed in absorption towards distant high-mass star-forming regions (SFRs)...
We discuss the detection of absorption by interstellar hydrogen fluoride (HF) along sight line to submillimeter continuum sources W49N and W51. have used Herschel's HIFI instrument in dual beam switch mode observe 1232.4762 GHz J = 1 - 0 HF transition upper sideband band 5a receiver. detected foreground toward both over a wide range velocities. Optically thin components were on lines, allowing us measure as opposed obtain lower limit column density for first time. As previous observations...
We report the detection of strong absorption by interstellar hydrogen fluoride along sight-line to submillimeter continuum source G10.6–0.4 (W31C). have used <i>Herschel<i/>'s HIFI instrument, in dual beam switch mode, observe 1232.4763 GHz <i>J<i/> = 1–0 HF transition upper sideband Band 5a receiver. The resultant spectrum shows weak emission from at LSR velocities range –10 –3 km s<sup>-1<sup/>, accompanied foreground material 15 50 s<sup>-1<sup/>. is similar that 1113.3430...
Context. Models of pure gas-phase chemistry in well-shielded regions molecular clouds predict relatively high levels oxygen, O2, and water, H2O. These abundances imply cooling rates, leading to short timescales for the evolution gravitationally unstable dense cores, forming stars planets. Contrary expectations, dedicated space missions SWAS Odin typically found only very small amounts water vapour essentially no O2 star-forming interstellar medium.
Aims. The comparative study of several molecular species at the origin gas phase chemistry in diffuse interstellar medium (ISM) is a key input unraveling coupled chemical and dynamical evolution ISM. Methods. lowest rotational lines HCO+, HCN, HNC, CN were observed IRAM-30m telescope absorption against \lambda 3 mm 1.3 continuum emission massive star-forming regions Galactic plane. probe over kiloparsecs along these sight. excitation temperatures HCO+ are inferred from comparison absorptions...
We report the detection of ground state <i>N<i/>,<i>J<i/> = 1,3/2 1,1/2 doublet methylidyne radical CH at ~532 GHz and ~536 with <i>Herschel<i/>/HIFI instrument along sight-line to massive star-forming regions G10.6–0.4 (W31C), W49N, W51. While molecular cores associated these show <i>emission<i/> lines, clouds in diffuse interstellar medium are detected <i>absorption<i/> against strong submillimeter background. The combination hyperfine structure emission absorption results complex...
The radical ion HCl+, a key intermediate in the chlorine chemistry of interstellar gas, has been identified for first time medium with Herschel Space Observatory's Heterodyne Instrument Far-Infrared. ground-state rotational transition H35Cl+, 2Π3/2J = 5/2–3/2, showing Λ-doubling and hyperfine structure, is detected absorption toward Galactic star-forming regions W31C (G10.6-0.4) W49N. complex features are modeled by convolving velocity space opacity profiles other molecular tracers same...
In patients with cirrhosis and small hepatocellular carcinoma (HCC), thermal ablation is currently recognized as an effective local treatment. Among procedures, radiofrequency (RFA) the most diffusely used standard against which any new treatment should be compared. retrospective studies, laser (LA) resulted safe RFA. Therefore, we performed a non-inferiority randomized trial comparing RFA LA in HCC within Milan criteria.Overall, 140 157 nodules were randomly assigned to receive or LA. The...
An unexpected increased HCC recurrence and occurrence rate among HCV patients treated with direct acting antivirals combination has been reported. Aim of the study was evaluation early its risk factors in a infected population, direct-acting-antivirals. According to Italian ministerial guidelines for direct-acting-antivirals treatment, 1022 consecutive were enrolled. Patients either active at imaging or history previous HCC, HBV HIV co-infection, liver transplant recipients excluded. The...
The HIFI instrument on board the Herschel Space Observatory has been used to observe interstellar nitrogen hydrides along sight-line towards G10.6-0.4 in order improve our understanding of chemistry nitrogen. We report observations absorption NH N=1-0, J=2-1 and ortho-NH2 1_1,1-0_0,0. also observed ortho-NH3 1_0-0_0, 2_0-1_0, para-NH3 2_1-1_1, searched unsuccessfully for NH+. All detections show emission associated directly with hot-core source itself as well by foreground material over a...
We have used the Herschel-HIFI instrument to observe interstellar nitrogen hydrides along sight-lines towards W49N and G10.6-0.4 in order elucidate production pathways leading nitrogen-bearing species diffuse gas. All detections show absorption by foreground material over a wide range of velocities, as well associated directly with hot-core source itself. As previously published observations G10.6-0.4, NH, NH2 NH3 spectra strikingly similar non-saturated features. decompose into different...
We present Herschel/HIFI observations of the three ground state transitions H2O (556, 1669, and 1113 GHz) H218O (547, 1655, 1101 GHz)—as well as first few excited (987, 752, 1661 GHz)—toward six high-mass star-forming regions, obtained part PRISMAS (PRobing InterStellar Molecules with Absorption line Studies) Guaranteed Time Key Program. Water vapor associated translucent clouds in Galactic arms is detected absorption along every sight all transitions. The continuum sources exhibit broad...
Ionized carbon is the main gas-phase reservoir of in neutral diffuse interstellar medium and its 158 micron fine structure transition [CII] most important cooling line (ISM). We combine absorption emission spectroscopy to gain an improved understanding physical conditions different phases ISM. present high resolution spectra obtained with Herschel/HIFI instrument towards bright dust continuum sources regions Galactic plane, probing simultaneously gas along sight background high-mass star...
Using the Herschel Space Observatory's Heterodyne Instrument for Far-Infrared (HIFI), we have observed para-chloronium (H2Cl+) toward six sources in Galaxy. We detected interstellar chloronium absorption foreground molecular clouds along sight-lines to bright submillimeter continuum Sgr A (+50 km/s cloud) and W31C. Both para-H2-35Cl+ para-H2-37Cl+ isotopologues were detected, through observations of their 1(11)-0(00) transitions at rest frequencies 485.42 484.23 GHz, respectively. For an...
We report the detection of ground-state rotational transition methylidyne cation CH<sup>+<sup/> and its isotopologue <sup>13<sup/>CH<sup>+<sup/> toward remote massive star-forming regions W33A, W49N, W51 with HIFI instrument onboard <i>Herschel<i/> satellite. Both lines are seen only in absorption against dust continuum emission regions. The is saturated over almost entire velocity ranges sampled by lines-of-sight that include gas associated (SFR) Galactic foreground material. column...
We present Herschel/HIFI observations of the fundamental rotational transitions ortho- and para-H$_2^{16}$O H$_2^{18}$O in absorption towards Sagittarius~B2(M) W31C. The ortho/para ratio water foreground clouds on line sight these bright continuum sources is generally consistent with statistical high-temperature 3, within observational uncertainties. However, somewhat unexpectedly, we derive a low $2.35 \pm 0.35$, corresponding to spin temperature $\sim$27~K, at velocities expanding...
Abstract Purpose: To describe and test a new fully automatic lesion detection system for breast DCE‐MRI. Materials Methods: Studies were collected from two institutions adopting different DCE‐MRI sequences, one with the other without fat‐saturation. The pipeline consists of (i) segmentation, to identify size location; (ii) registration, correct patient movements; (iii) detection, extract contrast‐enhanced regions using normalization technique based on contrast‐uptake mammary vessels; (iv)...
We present a ∼52–671 μm spectral scan toward Sgr A* taken with the PACS and SPIRE spectrometers on board Herschel. The achieved angular resolution allows us to separate, for first time at far-IR wavelengths, emission central cavity (gas in inner parsec of galaxy) from that surrounding circumnuclear disk. spectrum is dominated by strong [O iii], i], [C ii], [N i] fine-structure lines (in decreasing order luminosity) arising gas irradiated UV photons stellar cluster. In addition, rotationally...