A5063771589- Neural and Behavioral Psychology Studies
- Decision-Making and Behavioral Economics
- Heart Rate Variability and Autonomic Control
- Cancer Cells and Metastasis
- Visual perception and processing mechanisms
- Wnt/β-catenin signaling in development and cancer
- Epigenetics and DNA Methylation
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Behavioral Health and Interventions
- Neurotransmitter Receptor Influence on Behavior
- Glioma Diagnosis and Treatment
- Hearing, Cochlea, Tinnitus, Genetics
- Cellular Mechanics and Interactions
- Mindfulness and Compassion Interventions
- Neurogenesis and neuroplasticity mechanisms
- Social and Intergroup Psychology
- Mind wandering and attention
- Microtubule and mitosis dynamics
- MicroRNA in disease regulation
- Action Observation and Synchronization
- Cultural Differences and Values
- Blood Pressure and Hypertension Studies
- Multisensory perception and integration
- Face Recognition and Perception
- Autism Spectrum Disorder Research
Peking University
2023-2024
Chinese Institute for Brain Research
2023-2024
McGovern Institute for Brain Research
2023
Dalian Medical University
2018-2020
Kunming University of Science and Technology
2019
First People's Hospital of Yunnan Province
2017
Findings of racial ingroup biases in empathy and social behaviors require understanding relevant psychological brain mechanisms. Using self-report, behavioral, neuroimaging measures, we tested the hypothesis that identification provides a cognitive basis for altruistic decision-making. We showed mask training procedure using other-race facial disguises altered self-face perception promoted with other race. Shift modulated medial prefrontal activity, increased electrophysiological responses...
Abstract Previous research on racial ingroup bias in empathy for pain focused neural responses to a single person’s suffering. It is unclear whether simultaneously perceived multiple individuals’ (denoted as collective this study) also sensitive identities of targets. We addressed issue by recording electroencephalography from Chinese adults who responded 2 × arrays Asian or White faces which 4 faces, 1 face, no face showed painful expressions. Participants reported greater feelings others’...
Abstract Previous research has shown that feedback evaluation is sensitive to monetary incentive. We investigated whether this sensitivity driven by motivational salience (the difference between both rewarding and punishing events versus neutral events) or valence events). Fifty-seven participants performed a incentive delay task under gain context, loss context with their electroencephalogram recorded. During the time domain, feedback-related negativity (FRN) showed effect whereas P3...
Previous research has demonstrated that reward-related neural activity is enhanced for choice relative to no-choice opportunities in the gain context. The current event-related potential study examined whether this modulatory effect of can be observed both and loss contexts across anticipatory consummatory phases incentive processing. Thirty-two participants performed a simple task during which choices were made either by themselves (a condition) or computer context (gain vs nongain)...
Abstract Malignant glioma is a formidable disease that commonly leads to death, mainly due the invasion of tumor cells into neighboring tissues. Therefore, inhibition cell may provide an effective therapy for malignant glioma. Here we report nicotinic acid (NA), essential vitamin, inhibits in vitro and vivo . Treatment U251 with NA results reduced invasion, which accompanied by loss mesenchymal phenotype increase cell-cell adhesion. At molecular level, transcription adherens junction protein...
Both enhanced discrimination of low-level features auditory stimuli and mutations SHANK3 (a gene that encodes a synaptic scaffolding protein) have been identified in autism spectrum disorder patients. However, experimental evidence regarding whether lead to neural processing is lacking. The present study investigated this possibility by examining effects Shank3 on early pitch (tone frequency) dogs. We recorded electrocorticograms from wild-type mutant dogs using an oddball paradigm which...
Malignant glioma is a clinically formidable disease. It commonly leads to death within 5 years after diagnosis. Physicians are often baffled since the inevitable diffuse invasion deteriorates clinical outcomes rapidly. Therefore, cancerous infiltration presents foremost challenge all therapeutic strategies on glioblastoma multiforme (GBM). Previously, we demonstrated that nicotinic acid (NA) possesses brand new function by targeting F-actin stress fibers. By treating HEK293 or NIH3T3 cells...
The question of how the brain represents reward prediction errors is central to reinforcement learning and adaptive, goal-directed behavior. Previous studies have revealed error representations in multiple electrophysiological signatures, but it remains elusive whether these correlates underlying are sensitive valence (in a signed form) or salience an unsigned form). One possible reason concerns loose correspondence between objective probability subjective resulting from optimistic bias,...
Cancer stem cells are reportedly associated with drug resistance in glioma, but there conflicting findings on the effects of cancer resistance. The aim present study was to identify underlying mechanisms rat C6 glioma cells, through use Transwell invasion assays, flow cytometric and western blot analyses as well immunohistochemical staining. results revealed that acquisition by enhanced migration ability vivo vitro. Notably, did not depend increase a side population phenotype. Blockade ABC...
Abstract The sensation‐seeking trait is a potential endophenotype for various addictive behaviors. Using nonclinical sample, the current ERP study examined effects of sensation seeking on performance monitoring and response inhibition. Twenty high seekers 21 low were selected from large sample based their score performed stop‐signal task while EEG was recorded. High relative to displayed similar inhibition in terms measure stop‐P3 amplitudes. Compared seekers, however, exhibited reduced...
Cell migration is a finely tuned biological process that often involves epithelial-mesenchymal transition (EMT). EMT typically characterized by the upregulation of mesenchymal markers such as Snail1. This has been shown to be critical importance normal developmental processes, including neural crest and invasion. Interestingly, similar mechanisms are utilized in disease tumor metastasis migration. Notably, EMT-like processes confer cells with ability migrate, invade, adopt stem cell-like...
People usually give priorities to same-race over other-race individuals in cognition, emotion, and behavior. Reducing the racial biases requires understanding of their psychological brain mechanisms. To investigate functional role people’s identities ingroup favoritism social emotion prosocial behavior, we examined whether monoracial adults’ may be shifted toward a different one reduce empathy altruistic decision-making. We developed short-term training procedure shift Chinese from Asian...
Cell migration is a finely tuned biological process that often involves epithelial-mesenchymal transition (EMT). EMT typically characterized by the upregulation of mesenchymal markers such as Snail1. This has been shown to be critical importance normal developmental processes, including neural crest and invasion. Interestingly, similar mechanisms are utilized in disease tumor metastasis migration. Notably, EMT-like processes confer cells with ability migrate, invade, adopt stem cell-like...