Thomas W. Holmes

ORCID: 0000-0003-1683-423X
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
Research Areas
  • Medical Imaging Techniques and Applications
  • Advanced X-ray and CT Imaging
  • Radiation Dose and Imaging
  • Sinusitis and nasal conditions
  • Head and Neck Surgical Oncology
  • Nuclear Physics and Applications
  • Allergic Rhinitis and Sensitization
  • Cardiac Imaging and Diagnostics
  • Tuberculosis Research and Epidemiology
  • Nasal Surgery and Airway Studies
  • Nuclear reactor physics and engineering
  • Colorectal Cancer Treatments and Studies
  • Cancer Treatment and Pharmacology
  • Foreign Body Medical Cases
  • Drug-Induced Adverse Reactions
  • Graphite, nuclear technology, radiation studies
  • Lung Cancer Treatments and Mutations
  • Infectious Diseases and Mycology
  • Intestinal and Peritoneal Adhesions
  • Seismic Imaging and Inversion Techniques
  • Anesthesia and Neurotoxicity Research
  • Gastroesophageal reflux and treatments
  • Radioactivity and Radon Measurements
  • Cystic Fibrosis Research Advances
  • Asthma and respiratory diseases

Emory University
2019-2025

Royal College of Surgeons in Ireland
2023-2025

University of Oxford
2023-2024

Royal College of Surgeons of England
2024

Medtronic (United States)
2024

Georgia Institute of Technology
2024

Winship Cancer Institute
2023

Augusta University
2016-2022

Augusta University Health
2021

Georgia Regents Medical Center
2016

Abstract Background Beam hardening (BH) artifacts negatively influence computed tomography (CT) measurements, especially when due to dense materials or with high effective atomic numbers. Photon-counting detectors (PCD) are more susceptible BH equal weighting of photons regardless their energies. The problem is further confounded by the use contrast agents (CAs) K -edge in diagnostic CT energy range. We quantified effect different comparing energy-integrating detector (EID)-CT and PCD-CT....

10.1186/s41747-024-00530-5 article EN cc-by European Radiology Experimental 2025-03-19

Background Photon-counting CT (PCCT) represents a recent advancement in CT, offering improved spatial resolution and spectral separability. By using multiple adjustable energy bins, PCCT enables K-edge imaging, allowing mixed contrast agent distinction. Deep-silicon is new type of photon-counting detector with different characteristics compared cadmium detectors. Purpose To evaluate the performance prototype deep-Si scanner compare it that state-of-the-art dual-energy energy-integrating...

10.1148/radiol.231598 article EN Radiology 2024-06-01

No AccessJournal of Urology1 Nov 1953The Histologic Lesion Cholemic Nephrosis Thomas W. Holmes HolmesThomas View All Author Informationhttps://doi.org/10.1016/S0022-5347(17)67968-0AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail © 1953 by The American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 70Issue 5November 1953Page: 677-685 Advertisement Copyright & Permissions©...

10.1016/s0022-5347(17)67968-0 article EN The Journal of Urology 1953-11-01

Abstract Purpose 5-fluorouracil (5-FU) is inefficiently converted to the active anti-cancer metabolite, fluorodeoxyuridine-monophosphate (FUDR-MP), associated with dose-limiting toxicities and challenging administration schedules. NUC-3373 a phosphoramidate nucleotide analog of fluorodeoxyuridine (FUDR) designed overcome these limitations replace fluoropyrimidines such as 5-FU. Patients methods was administered monotherapy patients advanced solid tumors refractory standard therapy via...

10.1186/s13046-024-03010-1 article EN cc-by Journal of Experimental & Clinical Cancer Research 2024-04-02

Background Montelukast is used in the treatment of allergic rhinitis and asthma. It has been as adjuvant therapy patients with chronic rhinosinusitis (CRS), but its effectiveness not evaluated. This study evaluates efficacy leukotriene receptor antagonism CRS subtypes. Methods Retrospective review collected data at a tertiary-referral institution. We identified all who were prescribed montelukast postoperatively had lapse for least 1 month (n = 50), so that themselves serve their own control...

10.1002/alr.21649 article EN International Forum of Allergy & Rhinology 2016-02-02

10.1136/bmj.s3-4.193.795-a article EN BMJ 1856-09-13

Abstract Background Underutilization of implantable cardioverter defibrillators (ICD) to prevent sudden cardiac death (SCD) in post-myocardial infarction (MI) patients remains an issue across several geographies. A better understanding risk factors for SCD post-MI from regions with low ICD adoption rates will help identify those who benefit ICD. This analysis assessed all-cause and cardiovascular-related mortality the Improve Sudden Cardiac Arrest (SCA) Bridge Trial. Results For entire...

10.1186/s43044-024-00505-2 article EN cc-by The Egyptian Heart Journal 2024-06-07

10.1136/bmj.2.1354.1146 article EN BMJ 1886-12-11

10.1016/s0022-5223(19)32980-0 article EN Journal of Thoracic and Cardiovascular Surgery 1962-08-01

Background Chronic rhinosinusitis (CRS) is a local inflammatory process driven by eosinophils. Mucosal eosinophil count (MEC) has previously been demonstrated to be reliable indicator of disease severity. We aim evaluate use MEC in guiding medical management CRS after functional endoscopic sinus surgery (FESS). Methods retrospectively reviewed patients with who underwent FESS from 2004 2017. Tissue per high‐power field (HPF) was determined pathologic examination. MECs were compared polyp...

10.1002/alr.22517 article EN International Forum of Allergy & Rhinology 2020-01-12

The presence of eosinophilia and nasal polyps are well-established prognostic indicators chronic rhinosinusitis (CRS). importance demographic background, such as age, independent variables has not been elucidated while taking these factors into account.Respective review.CRS patients who underwent primary surgical treatment were subdivided based on age (young adults = 18-39, 40-64, elderly 65+). Groups then tissue polyposis. Sinonasal Outcome Test (SNOT-22), Lund-Kennedy (LK) endoscopy...

10.1177/0003489420919124 article EN Annals of Otology Rhinology & Laryngology 2020-05-09

10.1016/0002-9610(62)90158-7 article EN The American Journal of Surgery 1962-04-01

Tim BojL

10.1136/bmj.1.2568.689 article EN BMJ 1910-03-19

Two patients are presented, in whom right common carotid artery-internal jugular vein fistula had been patent for 12 years. These cases provide the longest reported follow-up of with surgically created carotid-jugular fistulas. Marked cardiac hypertrophy, a systolic murmur one patient, and arterial hypertension other, proved reversible following repair Alterations circulatory dynamics before after correlated established phenomena associated arteriovenous fistulas various size, duration,...

10.1161/01.cir.29.6.905 article EN Circulation 1964-06-01

Objectives/Hypothesis A number of autoimmune disorders (ADs) are associated with a spectrum sinonasal manifestations comparable to chronic rhinosinusitis (CRS). Our objective was study the subjective and measurements ADs. Study Design Retrospective cohort study. Methods All patients ADs referred our tertiary care rhinology clinic from 2008 2019 symptoms were compared randomly selected cohorts noneosinophilic CRS without nasal polyps (neCRSsNP) eosinophilic CRSsNP (eCRSsNP). Demographic data,...

10.1002/lary.28693 article EN The Laryngoscope 2020-04-23
Coming Soon ...