A5036380097- Nanoparticles: synthesis and applications
- Microplastics and Plastic Pollution
- Environmental Toxicology and Ecotoxicology
- Pharmaceutical and Antibiotic Environmental Impacts
- Graphene and Nanomaterials Applications
- Effects and risks of endocrine disrupting chemicals
- Electrochemical Analysis and Applications
- Birth, Development, and Health
- Education Pedagogy and Practices
- Maternal and Neonatal Healthcare
- Pesticide and Herbicide Environmental Studies
- Male Reproductive Health Studies
- Emergency and Acute Care Studies
- Advanced biosensing and bioanalysis techniques
- Insect and Pesticide Research
- Pregnancy and preeclampsia studies
- Prenatal Screening and Diagnostics
- biodegradable polymer synthesis and properties
- Linguistics and Education Research
- Reproductive Health and Contraception
- Congenital Anomalies and Fetal Surgery
- Zebrafish Biomedical Research Applications
- Business and Management Studies
- Folate and B Vitamins Research
- Education and Digital Technologies
University of Aveiro
2007-2024
Secretaria da Saúde
2024
Universidade Federal do Rio Grande
2024
Hospital de Sant Pau
2024
Centro Hospitalar de Lisboa Central
2023-2024
Centro Universitário Barão de Mauá
2024
Administração Regional de Saúde de Lisboa e Vale do Tejo
2024
Hospital Prof. Dr. Fernando Fonseca
2024
Centro Hospitalar do Baixo Vouga
2023
European Monitoring Centre for Drugs and Drug Addiction
2021
Ecotoxicity of cholinium-based ionic liquids.
Once in the aquatic ecosystems, nanoplastics (NPls) can interact with other contaminants acting as vectors of transport and altering their toxicological effects towards organisms. Thus, present study aims to investigate how polystyrene NPls (44 nm) herbicide phenmedipham (PHE) affect its toxicity zebrafish embryos. Single exposures 0, 0.015, 0.15, 1.5, 15 150 mg/L 0.02, 0.2, 2 20 PHE were performed. Embryos also exposed binominal combinations: 0.015 + PHE, 1.5 PHE. Due low solubility water,...
The terrestrial environment is one of the main recipients plastic waste. However, limited research has been performed on soil contamination by plastics and even less assessing effects nanoplastics (NPls). Behind potential toxicity caused per se, NPls are recognized vectors other environmental harmful contaminants. Therefore, aim present study to understand whether an industrial chemical (bisphenol A – BPA) a pharmaceutical (diphenhydramine DPH) changes in presence polystyrene invertebrate...
Silica nanoparticles (SiO
The main aim of the study is to evaluate effects pharmaceutical diphenhydramine (DPH) on embryo-larvae Danio rerio across distinct levels organization - individual and subcellular correlate those with DPH mode action (MoA) assessed by in silico analysis. An embryos heartbeat rate reduction was observed at 10 mg/L DPH, but 0.001 did not significantly affect zebrafish survival, hatching morphology. Larvae swimming distance decreased (hypoactivity) 1 DPH. Moreover, straightforward movements...
VACTERL association (OMIM 192350) is a non-random combination of multiple congenital malformations including vertebral, anal, cardiac, tracheoesophageal, renal and limb anomalies. The wide spectrum defects suggests the occurrence defective development during early embryogenesis. authors report case complex polymalformative detected by ultrasound in first trimester pregnancy. ensuing fetal study revealed presence anorectal, anomalies therefore was considered association. This generally...
Once in the environment, nanoplastics (NPls) may interact with other contaminants, such as pharmaceuticals, potentially acting carriers and modulating their toxicity. Thus, main aim of current study is to investigate how polystyrene (PS) NPls (mean diameter: 60 nm) simvastatin (SIM), an anticholesterolemic drug, modulate its toxicity zebrafish (Danio rerio) embryos. PS were carboxyl group functionalized, promote interaction/binding SIM (worst-case scenarios) it was fluorescently dyed,...
Nanoplastics (NPLs) became ubiquitous in the environment, from air we breathe to food eat. One of main concerns about NPLs risks is their role as carrier other environmental contaminants, potentially increasing uptake, bioaccumulation and toxicity organisms. Therefore, aim this study was understand how presence polystyrene (∅ 44 nm) will influence (synergism, additivity or antagonism) antihistamine diphenhydramine (DPH), towards zebrafish (Danio rerio) embryos, when dual mixtures. After 96...
From the start of 21st century, nanoecotoxicological research has been growing in fast steps due to need evaluate safety increasing use engineered nanomaterials. Boron (B) and vanadium (V) nanoparticles (NPs) generated by anthropogenic activities are subsequently released environment; therefore, organisms can be continuously exposed these NPs for short or long periods. However, long-term effects BNPs VNPs on soil unknown. This work aimed recognize describe their potential toxicological model...
Plastics in all shapes and sizes have become widespread across ecosystems due to intense anthropogenic use. As such, they can interact with other contaminants that accumulate the terrestrial environment, such as pharmaceuticals, metals or nanomaterials (NMs). These interactions potentiate combined toxic effects exposed soil organisms, hazardous long-term consequences full ecosystem. In present study, a model species, Enchytraeus crypticus (oligochaeta), was through contaminated...
Interaction of nanoplastics (NPls) with other environmental contaminants could affect their uptake by the organisms and toxicity. Thus, present study aims to investigate polystyrene NPls (44 nm) interaction antidepressant amitriptyline (AMI) its toxicity Danio rerio embryos. A similar toxicological profile for + AMI exposure was found most evaluated endpoints, comparing single exposure, showing that presence did not modulate However, behavioral assessment showed a different pattern...
Worldwide, pesticides have contaminated the environment, affecting non-target species. The aim of this work was to evaluate effects fosetyl-Al (FOS) on model organisms. Based 3 Rs for animal research and described guidelines, OECD 236 220 were applied with some modifications. FOS test concentrations 0.02–0.2–2–20–200 mg/L Danio rerio 250–500–750–1000–1250 mg/kg Enchytraeus crypticus. Besides standard endpoints, additional endpoints evaluated (D. rerio: behavior biochemical responses; E....