A5083289361- Acute Myocardial Infarction Research
- Diabetes Management and Research
- Gastric Cancer Management and Outcomes
- Pancreatic function and diabetes
- Diabetes and associated disorders
- Heart Failure Treatment and Management
- Enhanced Recovery After Surgery
- Advanced Glycation End Products research
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Liver Disease Diagnosis and Treatment
- Blood Pressure and Hypertension Studies
- Diet, Metabolism, and Disease
- Inflammatory Biomarkers in Disease Prognosis
- Bariatric Surgery and Outcomes
- Vitamin D Research Studies
- Cardiac electrophysiology and arrhythmias
- Cardiovascular Function and Risk Factors
- Diet and metabolism studies
- Mesenchymal stem cell research
- COVID-19 Clinical Research Studies
- Peripheral Neuropathies and Disorders
- Medication Adherence and Compliance
- COVID-19 Prevention and Impact
- Hydrogen's biological and therapeutic effects
- Mangiferin and Mango Extracts
Bakırköy Dr.Sadi Konuk Eğitim ve Araştırma Hastanesi
2017-2024
Sağlık Bilimleri Üniversitesi
2021-2024
University of Health Science
2022-2024
University of Health Sciences
2022
Istanbul University
2013-2021
İstanbul Eğitim ve Araştırma Hastanesi
2021
Czech Academy of Sciences, Institute of Experimental Medicine
2013
The aim of this clinical trial was to control the cytokine storm by administering mesenchymal stem cells (MSCs) critically-ill COVID-19 patients, evaluate healing effect, and systematically investigate how treatment works. Patients with moderate critical manifestations were separated as Group 1 (moderate cases, n = 10, treated conventionally), 2 (critical 3 conventionally plus MSCs transplantation therapy three consecutive doses on days 0, 3, 6, (as × 106 cells/kg, intravenously). mechanism...
Ozone is claimed to have beneficial effects. While studies revealed the safe therapeutic use of ozone, there are conflicting results for link between immune system and ozone encounter. Natural killer (NK) cells important sentinels immunity with their cytotoxic activity immune-regulatory potentials. This study aimed investigate effects direct encountering on human system, at cellular level. Survival, proliferative capacity subset content peripheral blood mononuclear (PBMC) were analysed. PBMC...
When the studies are evaluated, immunomodulatory effect of MSCs, administration in critically ill patients, obstacle situations use and side effects, pulmonary fibrosis prevention, which stem cells their products, regeneration effect, route, dosage listed under main heading like. The MSC on DNA repair genes COVID-19 infection is unknown. Our aim to determine mesenchymal (MSCs) therapy applied patients with coronavirus pathways associated those pathways. Patients (n = 30) divided into two...
Early diagnosis reduces mortality and morbidity rates in gastrointestinal system (GIS) anastomoses.The aim of the present study was to investigate importance some substances that were used detect major complications early patients who treated line with Enhanced Recovery After Surgery (ERAS) protocol for gastric cancer. Factors included interleukin-1β (IL-1β), tumor necrosis factor-α (TNF-α), C-reactive protein (CRP), procalcitonin (PCT) white blood cell (WBC).A hundred twenty underwent...
The diagnostic role of serum cytokines depends on the etiology and pathogenesis acute appendicitis but clinical significance these in differential diagnosis complicated remains unclear. To investigate prediction progression values interleukin-6, interleukin-1 beta, tumor necrosis factor-alpha appendicitis. This study was conducted 100 patients with a definitive 20 individuals assigned for control group. Venous blood collected to assess biochemical tests, as well interleukin-1β, factor-α...
Introduction . Hypertension (HT) is a common serious condition associated with cardiovascular morbidity and mortality. The pathogenesis of HT multifactorial has been widely investigated. Besides the vascular, hormonal, neurological factors, inflammation plays crucial role in HT. Many inflammatory markers such as C-reactive protein, cytokines, adhesion molecules have studied HT, which supported Presepsin (PSP) novel biomarker inflammation. Therefore, potential relationship between PSP was...
Abstract Background Cardiac troponins are the recommended markers for detection of acute myocardial infarction (AMI). There is a controversy regarding their decision limits. In this study, our objective was to reveal cut-off values high-sensitive troponin T (hsTnT) AMI diagnosis in population and examine effect age gender on hsTnT values. Methods Patients who presented emergency department (ED) with chest pain were selected, only those patients admitted during first 3–6 h symptom onset...
Objective:The aim of this study was to investigate the effect on coronavirus disease-2019 (COVID-19) glyoxal (GO), which is a precursor advanced glycation end-products, in diabetic and nondiabetic patients, treated hospital for COVID-19 who were similar age disease severity with comorbidities. Methods:The included 57 patients.Measurement GO made high-performance liquid chromatography method. Results:The values found be higher group than non-diabetic (p=0.001,p<0.01).The length stay longer...
Performing a diagnostic oral glucose tolerance test (OGTT) during pregnancy is important for early diagnosis of gestational diabetes mellitus. Hyperglycemia can be detected quickly, and mother the fetus protected. This study aimed to research relationship between blood sample tubes stability in pregnant women undergoing OGTT. Blood samples were taken at 120th minute after loading from 20 volunteers who underwent OGTT (75g). VACUETTE CAT Serum Separator (Clot Activator Tube) was used serum;...
Abstract Background To be able to prevent morbid obesity in the long-term, laparoscopic sleeve gastrectomy (LSG) is one of most effective surgical interventions. However, leakage and bleeding from stapler line are significant complications. The aim this study was determine role levels plasma presepsin detection leakage. Materials methods included 300 patients with LSG due 40 control subjects. Before any medical treatment applied, blood samples were taken at 12 h preoperatively on days 1, 3,...
Introduction: Acute coronary syndrome (ACS) remains as a single biggest cause of death worldwide.Heart-type fatty acid -binding protein (h-FABP) and myoglobin are small proteins present in the myocyte cytosol.In cases myocardial damage, they can freely pass into bloodstream.Thus, might be useful diagnosis ACS.The aim this prospective study was to search relationship between h-FABP levels disease severity mortality.Methods: One hundred-fourty-nine male patients with ST-elevation infarction...
Background:Vitamin D deficiency has become global health problem and it is associated with metabolic syndrome, type 2 diabetes mellitus, cancer, cardiovascular diseases increased mortality.The aim of this study to shed light on the 25 OH vitamin status in different age groups Turkish children.Materials Method: 1597 children (753 boys (47.2 %) 844 girls (52.8 %)) admitted Pediatry Outpatient Clinic were enrolled study.25 analysis was performed from venous blood samples using Cobas e411...
Abstract Background Autologous platelet rich plasma (PRP) is the concentration obtained from thrombocytes in plasma. During healing process, platelets are activated and then release granules which stimulate inflammatory cascade process. Platelet derived growth factor, vascular endothelial factor (VEGF), transforming β (TGFβ), epidermal (EGF) fibroblast (FGF) valuable markers used for cell regeneration. The aim of this study was to investigate potential effects PRP treatment on neomucosa...
Abstract Background The aim of this study was to investigate the importance fibrinopeptide-A and fibrinopeptide-B, which occur during formation D-dimer, most commonly used laboratory parameter, in early diagnosis acute mesenteric ischemia (AMI). Materials methods This experimental performed 30 male pathogen-free Wistar albino rats. animals were divided into 3 equal groups: Control group (n = 10), Sham 10) Ischemia 10). Blood samples taken 0, 1, 3, 6 h after simulation ischemia. Results...
The main culprit behind most cancers is the accumulation of reactive oxygen species. Glyoxal (GO) and methylglyoxal (MGO) are intermediates created by food processing they precursors advanced glycation end products (AGE) that cause glycative stress. We aimed to evaluate relationship between AGE levels healthy volunteers treatment-naive patients diagnosed with colorectal cancer. study consisted cancer who underwent routine colonoscopy. was conducted a total 42 cases, 47.6% (n = 20) female....
The prevalence of diabetes mellitus is growing worldwide, as well in the aging population, and its comorbidity mortality rates are higher people than they young people. It has been observed that number drugs used increases patients, especially diabetic patients. This study aimed to investigate relationship between polypharmacy modified Charlson Comorbidity Index (CCI) Katz Independence Activities Daily Living (Katz ADL) scores non-diabetic patients.This prospective included 184 62 subjects...