A5048771145- Tendon Structure and Treatment
- Extracellular vesicles in disease
- Shoulder Injury and Treatment
- Mesenchymal stem cell research
- Osteoarthritis Treatment and Mechanisms
- Orthopedic Surgery and Rehabilitation
- Bone fractures and treatments
- Knee injuries and reconstruction techniques
- Foot and Ankle Surgery
- Sports injuries and prevention
- Tissue Engineering and Regenerative Medicine
- Total Knee Arthroplasty Outcomes
- Pluripotent Stem Cells Research
- Cell Adhesion Molecules Research
- Biomedical and Engineering Education
- Sarcoma Diagnosis and Treatment
- Biomedical Ethics and Regulation
- Bone and Joint Diseases
- Cardiovascular Effects of Exercise
- Signaling Pathways in Disease
- Limits and Structures in Graph Theory
- Musculoskeletal synovial abnormalities and treatments
- Tracheal and airway disorders
- Congenital limb and hand anomalies
- Bone health and treatments
Western University of Health Sciences
2020-2024
Riverside University Health System - Medical Center
2022-2024
Children's Hospital of Orange County
2022-2024
Valley Health System
2024
University of Southern California
2018-2023
Southern California Clinical and Translational Science Institute
2023
University of Washington
2023
Seattle University
2023
Memorial Hospital
2023
Boston University
2022
Background: Fractures of the distal tibial epiphysis in children are often accompanied by articular surface disruption. With increased displacement, internal fixation is frequently performed with an epiphyseal screw to close fracture gap. Despite limited, high-level clinical evidence support implant removal, screws commonly removed after healing due potentially contact forces on tibiotalar joint. The purpose this study was investigate and compare outcomes complications that underwent...
Extracellular ribosomal proteins secreted in exosomes elicit biological/regenerative responses; however, contained the of ischemia-challenged epicardial adipose tissue-derived stem cells (EATDS) remain unexplored. This study focuses on identification EATDS and their sub-populations based key using single-cell genomics. Exosomes were isolated from control, ischemic (ISC), reperfused (ISC/R) harvested hyperlipidemic microswine, detected Liquid chromatography with tandem mass spectrometry...
Prenylsurfactants [(CH3)2C═CH(CH2)nSO3– Na+ (n = 4, 6, or 8)] were designed to probe the "ene" reaction mechanism of singlet oxygen at air–water interface. Increasing number carbon atoms in hydrophobic chain caused an increase regioselectivity for a secondary rather than tertiary surfactant hydroperoxide, arguing orthogonal alkene on water. The use water, deuterium oxide, and H2O/D2O mixtures helped distinguish mechanistic alternatives homogeneous solution conditions that include dewetting π...
Background/Aim: Plantar warts are cutaneous lesions on the plantar aspect of foot caused by infection keratinocytes with human papillomavirus (HPV). The severity and magnitude can vary, but they cause pain discomfort for all age groups. treatment remains a continuing challenge. purpose this research was to compare efficacy safety naturally derived Nowarta110 topical formula versus matching placebo in treating warts. Patients Methods: study is randomized, double-blind, parallel assignment...
The goal of this pilot study was to investigate the effects exosomes derived from synovial fluid-derived cells (SFDCs) cultured under normoxic conditions in a two-dimensional (2D) monolayer or encapsulated within three-dimensional (3D) matrix for chondrogenic differentiation vitro and cartilage defect repair vivo.Synovial fluid samples were obtained three patients, SFDCs isolated expanded either 2D culture seeded transglutaminase cross-linked gelatin (Col-Tgel) create 3D gel culture....
Exosomes are extracellular vesicles (EVs) released from cells that a part of many biological and pathological processes, especially in intercellular communication. These involved cell signaling, influence tissue immune response, serve as biomarkers for diseases. Most interesting the exosomes mesenchymal stem (MSCs) inflammation joint Preliminary studies have demonstrated advantages using EVs rather than MSCs free therapy. Research on shown promising results tracking pathogenesis prognosis...
Objective Alteration of the cellular microenvironment may influence intra- and intercellular communication contribute to cartilage injury repair. The purpose this study was investigate how matrix elasticity/stiffness affects chondrogenic activities, including cell survival, phenotypic expression, release both pro- anti-inflammatory cytokines. Design Human articular chondrocytes (HACs) cultured on traditional 2-dimensional (2D) plastic surfaces were compared with those within 3D hydrogel...