Colin Doyle

ORCID: 0000-0003-1704-2576
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About
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Research Areas
  • Iron oxide chemistry and applications
  • Minerals Flotation and Separation Techniques
  • 3D Printing in Biomedical Research
  • Inhalation and Respiratory Drug Delivery
  • Metal Extraction and Bioleaching
  • Molecular Junctions and Nanostructures
  • Mine drainage and remediation techniques
  • Neuroscience and Neural Engineering
  • Drug Solubulity and Delivery Systems
  • Geochemistry and Elemental Analysis
  • Advanced biosensing and bioanalysis techniques
  • Nanofabrication and Lithography Techniques
  • Microencapsulation and Drying Processes
  • Radioactive element chemistry and processing
  • Bacterial biofilms and quorum sensing
  • Antimicrobial agents and applications
  • Ion-surface interactions and analysis
  • Environmental remediation with nanomaterials
  • Mass Spectrometry Techniques and Applications
  • Electron and X-Ray Spectroscopy Techniques
  • Inorganic Fluorides and Related Compounds
  • Polymer crystallization and properties
  • Force Microscopy Techniques and Applications
  • Plasmonic and Surface Plasmon Research
  • Asthma and respiratory diseases

University of Auckland
2010-2024

University of Oxford
2024

Keele University
2014

Dublin City University
2011

University of Namur
2011

Stanford University
1999-2005

Stanford Synchrotron Radiation Lightsource
2004

Lawrence Berkeley National Laboratory
2004

Jefferson College
1972

<h3>PURPOSE</h3> We aimed to determine the effects of implementing risk-stratified care for low back pain in family practice on physician's clinical behavior, patient outcomes, and costs. <h3>METHODS</h3> The IMPaCT Back Study (IMplementation improve Patient Care through Targeted treatment) prospectively compared separate cohorts a preintervention phase (6 months usual care) postintervention (12 stratified practice, involving 64 physicians linked physical therapy services. A total 1,647...

10.1370/afm.1625 article EN The Annals of Family Medicine 2014-03-01

Point-of-care (POC) diagnostics implementing microfluidic technology on single use disposable plastic chips has potential applications in personalized medicine, clinical and global health. However, the challenges commercializing POC devices must be addressed. Immobilization of biomolecules to through appropriate surface functionalization is a key issue for fabrication new generation biomedical diagnostic devices. The most important requirements practicable process are speed, control...

10.1039/b925737c article EN Journal of Materials Chemistry 2010-01-01

The speciation of chromium in overlayers on atomically clean surfaces single crystal magnetite (Fe3O4) and hematite (α-Fe2O3) were studied using Cr L-edge, Fe O K-edge X-ray absorption spectra collected with synchrotron radiation. produced by reaction the 5 mM or 50 μM Na2CrO4 aqueous solutions a N2-filled glove bag opaque containers at exposure times ranging from 1 min to over 60 min. data acquired total electron yield more surface-sensitive Auger detection. 1s, 2p, 2p photoemission taken...

10.1016/s0039-6028(98)00940-6 article EN cc-by-nc-nd Surface Science 1999-04-01

Defect-free pyrite (100) surfaces were generated and a controlled manipulation of sulfur defect density at these was performed. Sulfur species different coordination environments the surface probed by $\mathrm{S}$ $2p$ photoemission in combination with theoretical modeling core-level shifts. A strict structural assignment peaks ${\mathrm{FeS}}_{2}(100)$ low regime achieved. Based on our results, that is related to vacancy confirmed provide active site for rapid initial oxidation pyrite.

10.1103/physrevb.70.195404 article EN Physical Review B 2004-11-05

Both latent and multidrug-resistant tuberculosis (TB) have been causing significant concern worldwide. A novel drug, pretomanid (PA-824), has shown a potent bactericidal effect against both active forms of Mycobacterium (MTb) synergistic when combined with pyrazinamide moxifloxacin. This study aimed to develop triple combination spray dried inhalable formulations composed antitubercular drugs, pretomanid, moxifloxacin, (1:2:8 w/w/w), alone (PaMP) in an aerosolization enhancer, L-leucine (20...

10.1016/j.ijpharm.2024.123984 article EN cc-by International Journal of Pharmaceutics 2024-03-09

The surface science of bioassay devices is great importance in the development modern diagnostic platforms. quality one most important elements device, often governing background response, hence controlling sensitivity an assay. Detailed characterization and analysis are imperative for preparation reproducible coatings with desired properties. We performed a comprehensive 3-aminopropyl-triethoxysilane films prepared under two different deposition conditions on COP slides. Two sets slides...

10.1039/b924692d article EN The Analyst 2010-01-01

Silver thin films are well known as the most sensitive material for surface plasmon resonance (SPR) based analysis. However, use of silver this purpose is limited by three main issues, namely poor adhesion to plastic substrates, chemical instability in both air and aqueous environments hence difficulty functionalizing coated substrate immobilizing biomolecular ligands conventional liquid phase methods. In work, we have successfully addressed these problems using gas-phase coating processes....

10.1039/c2an35826c article EN The Analyst 2012-01-01

A siloxane surface-anchored quaternary ammonium salt (AQAS: BIOSAFE HM4100 in this study) has been chemisorbed onto a quartz substrate. The aim of study is to elucidate, using atomic force microscopy (AFM) and X-ray photoelectron spectroscopy (XPS), the structure AQAS layers. biocide includes C18 alkyl chain previously invoked lysis potency. coverage appears zones on surface, which include first layer (2.6 ± 0.1 nm) multilayering that were explored AFM. XPS data exhibited two N 1s signals at...

10.1021/acs.langmuir.8b00535 article EN Langmuir 2018-03-30

Aluminum is highly abundant in the Earth's crust where it present a wide variety of primary and secondary aluminosilicate minerals, amorphous phases, aqueous solution species.The speciation coordination AI many these particularly those that are X-ray or as thin surface coatings, often unknown based on indirect methods.We have utilized aluminum K-edge XANES study nature several such specifically rich phases soils surfaces quartz feldspar grains loess, substitution iron oxyhydroxides.In...

10.1107/s0909049598015568 article EN Journal of Synchrotron Radiation 1999-05-01

Abstract Following bilateral simple mastoidectomy, eight adult squirrel monkeys were subjected to argon laser irradiation (output wavelength of 488 nanometers) the horizontal or posterior semicircular canals. Penetration bony canal wall and damage membranous labyrinth was achieved if multiple superimposed burns made (one watt bursts with durations from 0.2 1 second). The major morphologic effect penetrating lesions a mild prolific growth fibrous tissue restricted immediate site irradiation....

10.1288/00005537-197206000-00014 article EN The Laryngoscope 1972-06-01
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